1LNSA

Crystal structure analysis of the x-prolyl dipeptidyl aminopeptidase from lactococcus lactis
Slipknot S +31 +31 +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 192-310 119 311-763 1-169 170-191 169 452 slipknot
Chain Sequence
MRFNHFSIVDKNFDEQLAELDQLGFRWSVFWDEKKILKDFLIQSPSDMTALQATAELDVIEFLKSSIELDWEIFWNIALQLLDFVPNFDFEIGKAFEYAKNSNLPQIEAEMTTENIISAFYYLLCTRRKTGMILVEHWVSEGLLPLDNHYHFFNDKSLATFDSSLLEREVLWVESPVDSEQRGENDLIKIQIIRPKSTEKLPVVMTASPYHLGINDKANDLALHDMNVELEEKTSHEIHVEQKLPQKLSAKAKELPIVDKAPYRFTHGWTYSLNDYFLTRGFASIYVAGVGTRSSDGFQTSGDYQQIYSMTAVIDWLNGRARAYTSRKKTHEIKASWANGKVAMTGKSYLGTMAYGAATTGVEGLELILAEAGISSWYNYYRENGLVRSPGGFPGEDLDVLAALTYSRNLDGADFLKGNAEYEKRLAEMTAALDRKSGDYNQFWHDRNYLINTDKVKADVLIVHGLQDWNVTPEQAYNFWKALPEGHAKHAFLHRGAHIYMNSWQSIDFSETINAYFVAKLLDRDLNLNLPPVILQENSKDQVWTMMNDFGANTQIKLPLGKTAVSFAQFDNNYDDETFKKYSKDFNVFKKDLFENKANEAVIDLELPSMLTINGPVELELRLKLNDTKGFLSAQILDFGQKKRLEDKVRVKDFKVLDRGRNFMLDDLVELPLVESPYQLVTKGFTNLQNQSLLTVSDLKADEWFTIKFELQPTIYHLEKADKLRVILYSTDFEHTVRDNRKVTYEIDLSQSKLIIPIESVKN
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
2.1 193-451 259 1-167, 736-763 168-192, 452-735 167 28 slipknot
view details
1.1 191-295 105 1-168, 317-763 169-190, 296-316 168 447 slipknot
view details
2.1 180-385 206 1-168, 397-763 169-179, 386-396 168 367 slipknot
view details
1.1 182-395 214 1-168, 407-763 169-181, 396-406 168 357 slipknot
view details
2.1 187-333 147 1-169, 349-763 170-186, 334-348 169 415 slipknot
view details
1.1 183-395 213 1-181, 407-763 182-182, 396-406 181 357 slipknot
view details
1.1 191-429 239 1-169, 450-763 170-190, 430-449 169 314 slipknot
view details
2.1 181-379 199 1-171, 391-763 172-180, 380-390 171 373 slipknot
view details
2.1 193-358 166 1-179, 376-763 180-192, 359-375 179 388 slipknot
view details
1.1 190-316 127 1-180, 327-763 181-189, 317-326 180 437 slipknot
view details
1.1 192-395 204 1-182, 406-763 183-191, 396-405 182 358 slipknot
view details
2.1 193-379 187 1-183, 395-763 184-192, 380-394 183 369 slipknot
view details
2.1 193-394 202 1-183, 396-763 184-192, 395-395 183 368 slipknot
view details
2.1 194-386 193 1-192, 397-763 193-193, 387-396 192 367 slipknot
publication title The Structural Basis for Catalysis and Specificity of the X-prolyl dipepdidyl aminopeptidase from Lactococcus lactis
pubmed doi rcsb
structure length 763
molecule tags Hydrolase
source organism Lactococcus lactis
sequence length 763
molecule keywords X-PROLYL DIPEPTIDYL AMINOPEPTIDASE
ec nomenclature ec 3.4.14.11: Xaa-Pro dipeptidyl-peptidase.
pdb deposition date 2002-05-03
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02129 Peptidase_S15 X-Pro dipeptidyl-peptidase (S15 family)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.120.260 Mainly Beta Sandwich Jelly Rolls Galactose-binding domain-like 1lnsA04
3.40.50.1820 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold Rossmann fold 1lnsA02
3FSGA 1LNSA
chains in the KnotProt database with same CATH superfamily
3RDPA 3M4NA 3FSGA 3L04A 1E2NA 1KI6A 4IVPA 3KZKA 1QMGA 3KZCA 1DBIA 1R4MB 3L02A 2FG7C 1VTKA 1GKUB 4JBXA 3FR8A 2FG6C 2G7MC 1KI6B 3F0TA 1LNSA 1E2HA 1KI4A 1JS1X 3KZMA 3M5DA 3FR7A 1QHIA 1YRLA 1OF1A 3M5CA 3L05A 4IVRA 1E2IA 1KI3A 1P75A 2VTKA 1YH1A 1F48A 1YVEI 1E2LA 1KI8A 3M4JA 2XTJA 1E2PA 4JBYA 2FG7X 1E2JA 1KI2A 1P72A 1E2KA 3KZOA 1P7CA 2KI5A 3L06A 1E2MA 1KI7A 4IVQA 1R4NB 1KIMA 1P6XA 3VTKA 1OSNA 1P73A 3KZNA
chains in the KnotProt database with same CATH topology
3M4NA 3FSGA 3KZKA 1DBIA 3L02A 2FG7C 1GKUB 2FG6C 1LNSA 3M5CA 1JS1X 3KZMA 3M5DA 3KZCA 3L05A 3L04A 2XTJA 1YH1A 3KZNA 3M4JA 2FG7X 2G7MC 3KZOA 3L06A
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 3FSG A;  1LNS A; 
#chains in the KnotProt database with same CATH topology
 3RDP A;  3M4N A;  3FSG A;  3L04 A;  1E2N A;  1KI6 A;  4IVP A;  3KZK A;  1QMG A;  3KZC A;  1DBI A;  1R4M B;  3L02 A;  2FG7 C;  1VTK A;  1GKU B;  4JBX A;  3FR8 A;  2FG6 C;  2G7M C;  1KI6 B;  3F0T A;  1LNS A;  1E2H A;  1KI4 A;  1JS1 X;  3KZM A;  3M5D A;  3FR7 A;  1QHI A;  1YRL A;  1OF1 A;  3M5C A;  3L05 A;  4IVR A;  1E2I A;  1KI3 A;  1P75 A;  2VTK A;  1YH1 A;  1F48 A;  1YVE I;  1E2L A;  1KI8 A;  3M4J A;  2XTJ A;  1E2P A;  4JBY A;  2FG7 X;  1E2J A;  1KI2 A;  1P72 A;  1E2K A;  3KZO A;  1P7C A;  2KI5 A;  3L06 A;  1E2M A;  1KI7 A;  4IVQ A;  1R4N B;  1KIM A;  1P6X A;  3VTK A;  1OSN A;  1P73 A;  3KZN A; 
#chains in the KnotProt database with same CATH homology
 3M4N A;  3FSG A;  3KZK A;  1DBI A;  3L02 A;  2FG7 C;  1GKU B;  2FG6 C;  1LNS A;  3M5C A;  1JS1 X;  3KZM A;  3M5D A;  3KZC A;  3L05 A;  3L04 A;  2XTJ A;  1YH1 A;  3KZN A;  3M4J A;  2FG7 X;  2G7M C;  3KZO A;  3L06 A; 
1LNSA
similar chains in the KnotProt database (40% sequence similarity)

 
            
               
#similar chains in the KnotProt database (40% sequence similarity)
 1LNS A; 
               
               
           

KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling