1P72A

Crystal structure of ehv4-tk complexed with thy and adp
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Slipknot S +31
Knot core rangeKnot core lengthKnot tails rangeSlipknot tails rangeSlipknot loops rangeN-end lengthC-end lengthType
view details
+31 7-119 113 1-6 310-333 120-309 6 24 slipknot
Chain Sequence
SHMVTIVRIYLDGVYGIGKSTTGRVMASAASGGSPTLYFPEPMAYWRTLFETDVISGIYDTQN----------DAALITAHYQSRFTTPYLILHDHTCTLFGGNSLQRGTQPDLTLVFDRHPVASTVCFPAARYLLGDMSMCALMAMVATLPREPQGGNIVVTTLNVEEHIRRLRTRARIGEQIDITLIATLRNVYFMLVNTCHFLRSGRVWRDGWGELPTSCGAYKHRATQMDAFQERVSPELGDTLFALFKTQELLDDRGVILEVHAWALDALMLKLRNLNVFSADLSGTPRQCAAVVESLLPLMSSTLSDFDSASALERAARTFNAEMGV
sequence length 333
structure length 323
publication title Structural basis for the dual thymidine and thymidylate kinase activity of herpes thymidine kinases.
pubmed doi rcsb
molecule tags Transferase
molecule keywords Thymidine kinase
source organism Equid herpesvirus 4
missing residues 64-73
ec nomenclature ec 2.7.1.21: Thymidine kinase.
pdb deposition date2003-04-30
KnotProt deposition date2014-07-31

pfam database annotations

chain Pfam Accession CodePfam Family IdentifierPfam Description
A PF00693 Herpes_TKThymidine kinase from herpesvirus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.50.300 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold P-loop containing nucleotide triphosphate hydrolases 1p72A00
3RDPA 1E2NA 1KI6A 4IVPA 1VTKA 1KI6B 3F0TA 1E2HA 1KI4A 1QHIA 1OF1A 4JBXA 1E2IA 1KI3A 1P75A 2VTKA 1F48A 1E2LA 1KI8A 4IVRA 1E2PA 4JBYA 1E2JA 1KI2A 1P72A 1E2KA 1P7CA 2KI5A 1E2MA 1KI7A 4IVQA 1KIMA 1P6XA 1OSNA 1P73A 3VTKA
chains in the KnotProt database with same CATH superfamily
3RDPA 3M4NA 3FSGA 3L04A 1E2NA 1KI6A 4IVPA 3KZKA 1QMGA 3KZCA 3L02A 2FG7C 1VTKA 4JBXA 3FR8A 2FG6C 2G7MC 1KI6B 3F0TA 1LNSA 1E2HA 1KI4A 1JS1X 3KZMA 3M5DA 3FR7A 1QHIA 1YRLA 1OF1A 3M5CA 3L05A 4IVRA 1E2IA 1KI3A 1P75A 2VTKA 1YH1A 1F48A 1YVEI 1E2LA 1KI8A 3M4JA 2XTJA 1E2PA 4JBYA 2FG7X 1E2JA 1KI2A 1P72A 1E2KA 3KZOA 1P7CA 2KI5A 3L06A 1E2MA 1KI7A 4IVQA 1KIMA 1P6XA 3VTKA 1OSNA 1P73A 3KZNA
chains in the KnotProt database with same CATH topology
3RDPA 1E2NA 1KI6A 4IVPA 1VTKA 1KI6B 3F0TA 1E2HA 1KI4A 1QHIA 1OF1A 4JBXA 1E2IA 1KI3A 1P75A 2VTKA 1F48A 1E2LA 1KI8A 4IVRA 1E2PA 4JBYA 1E2JA 1KI2A 1P72A 1E2KA 1P7CA 2KI5A 1E2MA 1KI7A 4IVQA 1KIMA 1P6XA 1OSNA 1P73A 3VTKA
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 3RDP A;  1E2N A;  1KI6 A;  4IVP A;  1VTK A;  1KI6 B;  3F0T A;  1E2H A;  1KI4 A;  1QHI A;  1OF1 A;  4JBX A;  1E2I A;  1KI3 A;  1P75 A;  2VTK A;  1F48 A;  1E2L A;  1KI8 A;  4IVR A;  1E2P A;  4JBY A;  1E2J A;  1KI2 A;  1P72 A;  1E2K A;  1P7C A;  2KI5 A;  1E2M A;  1KI7 A;  4IVQ A;  1KIM A;  1P6X A;  1OSN A;  1P73 A;  3VTK A; 
#chains in the KnotProt database with same CATH topology
 3RDP A;  3M4N A;  3FSG A;  3L04 A;  1E2N A;  1KI6 A;  4IVP A;  3KZK A;  1QMG A;  3KZC A;  3L02 A;  2FG7 C;  1VTK A;  4JBX A;  3FR8 A;  2FG6 C;  2G7M C;  1KI6 B;  3F0T A;  1LNS A;  1E2H A;  1KI4 A;  1JS1 X;  3KZM A;  3M5D A;  3FR7 A;  1QHI A;  1YRL A;  1OF1 A;  3M5C A;  3L05 A;  4IVR A;  1E2I A;  1KI3 A;  1P75 A;  2VTK A;  1YH1 A;  1F48 A;  1YVE I;  1E2L A;  1KI8 A;  3M4J A;  2XTJ A;  1E2P A;  4JBY A;  2FG7 X;  1E2J A;  1KI2 A;  1P72 A;  1E2K A;  3KZO A;  1P7C A;  2KI5 A;  3L06 A;  1E2M A;  1KI7 A;  4IVQ A;  1KIM A;  1P6X A;  3VTK A;  1OSN A;  1P73 A;  3KZN A; 
#chains in the KnotProt database with same CATH homology
 3RDP A;  1E2N A;  1KI6 A;  4IVP A;  1VTK A;  1KI6 B;  3F0T A;  1E2H A;  1KI4 A;  1QHI A;  1OF1 A;  4JBX A;  1E2I A;  1KI3 A;  1P75 A;  2VTK A;  1F48 A;  1E2L A;  1KI8 A;  4IVR A;  1E2P A;  4JBY A;  1E2J A;  1KI2 A;  1P72 A;  1E2K A;  1P7C A;  2KI5 A;  1E2M A;  1KI7 A;  4IVQ A;  1KIM A;  1P6X A;  1OSN A;  1P73 A;  3VTK A; 
1P6XA 1P72A 1P73A 1P75A
similar chains in the KnotProt database (40% sequence similarity)
1P6XB 1P72B 1P73B 1P73C 1P73D 1P75B 1P75C 1P75D
similar chains in the pdb database (40% sequence similarity)

 
            
               
#similar chains in the KnotProt database (40% sequence similarity)
 1P6X A;  1P72 A;  1P73 A;  1P75 A; 
               
               
           
#similar chains in the pdb database (40% sequence similarity)
 1P6X B;  1P72 B;  1P73 B;  1P73 C;  1P73 D;  1P75 B;  1P75 C;  1P75 D; 
           

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