1NM6A

Thrombin in complex with selective macrocyclic inhibitor at 1.8a
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 27-239 213 1-26 250-287 240-249 26 38 slipknot
Chain Sequence
DCGLRPLFEKKSLEDKTERELLESYI---IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKEGQP--------SVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFG
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.1m 27-228 202 1-26 237-276 229-236 26 40 slipknot
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2.1m 27-236 210 1-26 241-276 237-240 26 36 slipknot
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2.1m 25-226 202 1-4, 229-276 5-24, 227-228 4 48 slipknot

KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling