3QS4A

Crystal structure of leut mutant f259v bound to sodium and l-tryptophan
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
  • Chain breaks within knot 41 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Slipknot S +31 41 +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 37-264 228 265-507 1-20 21-36 20 242 slipknot
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41 14-293 280 1-13 350-507 294-349 13 158 slipknot
Chain Sequence
REHWATRLGLILAMAGNAVGLGNFLRFPVQAAENGGGAFMIPYIIAFLLVGIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVVAIYYVYIESWTLGFAIKFLVGLVPEPP---TDPDSILRPFKEFLYSYIGVPKGDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFTLSLGVGAIITYASYVRKDQDIVLSGLTAATLNEKAEVILGGSISIPAAVAFFGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLTSSIAIMQPMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFWAGTIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRYITPAFLAVLLVVWAREYIPKIMEETHWTVWITRFYIIGLFLFLTFLVFLAERRRNHE
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.2 11-285 275 1-10 300-504 286-299 10 205 slipknot
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4.1 12-299 288 1-11 311-504 300-310 11 194 slipknot
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3.2m 9-320 312 1-8 327-504 321-326 8 178 slipknot
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3.2 13-334 322 1-12 347-504 335-346 12 158 slipknot
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3.2 14-316 303 1-7, 322-504 8-13, 317-321 7 183 slipknot
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3.2 14-321 308 1-7, 329-504 8-13, 322-328 7 176 slipknot
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2.1 29-253 225 1-15, 268-504 16-28, 254-267 15 237 slipknot
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2.1 21-272 252 1-15, 285-504 16-20, 273-284 15 220 slipknot
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2.1 41-351 311 1-18, 391-504 19-40, 352-390 18 114 slipknot
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2.1 26-273 248 1-20, 280-504 21-25, 274-279 20 225 slipknot
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1.1 32-245 214 1-21, 257-504 22-31, 246-256 21 248 slipknot
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1.1 37-242 206 1-24, 255-504 25-36, 243-254 24 250 slipknot
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1.1 37-254 218 1-31, 257-504 32-36, 255-256 31 248 slipknot
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1.1 40-272 233 1-25, 293-504 26-39, 273-292 25 212 slipknot
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1.1 38-245 208 1-36, 255-504 37-37, 246-254 36 250 slipknot
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2.1 39-404 366 1-27, 413-504 28-38, 405-412 27 92 slipknot
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2.1 38-394 357 1-30, 400-504 31-37, 395-399 30 105 slipknot
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2.1 40-261 222 1-33, 272-504 34-39, 262-271 33 233 slipknot
sequence length 507
structure length 504
publication title Insights into transport mechanism from LeuT engineered to transport tryptophan.
pubmed doi rcsb
molecule tags Transport protein
molecule keywords Na(+):neurotransmitter symporter (Snf family)
source organism Aquifex aeolicus
missing residues 128-130
total genus Genus: 206
ec nomenclature
pdb deposition date 2011-02-19
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00209 SNF Sodium:neurotransmitter symporter family
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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