3ULKA

E. coli ketol-acid reductoisomerase in complex with nadph and mg2+
Knot K 41 +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 252-365 114 1-230, 420-489 231-251, 366-419 230 70 slipknot
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41 223-422 200 1-222, 423-489 222 67 knot
Chain Sequence
MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVINLTPDKQHSDVVRTVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGKAIPEGAVDNGQLRDVNEAIRSHAIEQVGKKLRGYMTDMKRIAV
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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4.1 219-428 210 1-218, 429-489 218 61 knot
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3.2 217-417 201 1-216 433-489 418-432 216 57 slipknot
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4.1 220-433 214 434-489 1-218 219-219 218 55 slipknot
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2.1 239-370 132 1-220, 392-489 221-238, 371-391 220 98 slipknot
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1.1 242-416 175 1-227, 427-489 228-241, 417-426 227 63 slipknot
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1.1 242-426 185 1-228, 429-489 229-241, 427-428 228 61 slipknot
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3.1 249-372 124 1-237, 394-489 238-248, 373-393 237 96 slipknot
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3.1 250-372 123 1-248, 394-489 249-249, 373-393 248 96 slipknot
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2.1 257-414 158 1-246, 427-489 247-256, 415-426 246 63 slipknot
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2.1 259-367 109 1-247, 381-489 248-258, 368-380 247 109 slipknot
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2.1 259-380 122 1-249, 391-489 250-258, 381-390 249 99 slipknot
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1.1 258-393 136 1-247, 404-489 248-257, 394-403 247 86 slipknot
publication title Bacterial and plant ketol-acid reductoisomerases have different mechanisms of induced fit during the catalytic cycle
pubmed doi rcsb
structure length 489
molecule tags Oxidoreductase
source organism Escherichia coli
sequence length 489
molecule keywords Ketol-acid reductoisomerase
ec nomenclature ec 1.1.1.86: Ketol-acid reductoisomerase.
pdb deposition date 2011-11-11
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01450 IlvC Acetohydroxy acid isomeroreductase, catalytic domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1040.10 Mainly Alpha Orthogonal Bundle N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 3ulkA02
3FR7A 1YRLA 3FR8A 1QMGA 3ULKA 1YVEI
chains in the KnotProt database with same CATH superfamily
3FR7A 1YRLA 3FR8A 1QMGA 3ULKA 1YVEI
chains in the KnotProt database with same CATH topology
3FR7A 1YRLA 3FR8A 1QMGA 3ULKA 1YVEI
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 3FR7 A;  1YRL A;  3FR8 A;  1QMG A;  3ULK A;  1YVE I; 
#chains in the KnotProt database with same CATH topology
 3FR7 A;  1YRL A;  3FR8 A;  1QMG A;  3ULK A;  1YVE I; 
#chains in the KnotProt database with same CATH homology
 3FR7 A;  1YRL A;  3FR8 A;  1QMG A;  3ULK A;  1YVE I; 
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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