4D1DA

Structure of mhp1, a nucleobase-cation-symport-1 family transporter with the inhibitor 5-(2-naphthylmethyl)-l-hydantoin.
Slipknot S +31 41 +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 49-221 173 222-456 1-30 31-48 30 234 slipknot
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41 26-260 235 1-25 302-456 261-301 25 155 slipknot
Chain Sequence
SLLNPSNAPTRYAERSVGPFSLAAIWFAMAIQVAIFIAAGQMTSSFQVWQVIVAIAAGCTIAVILLFFTQSAAIRWGINFTVAARMPFGIRGSLIPITLKALLSLFWFGFQTWLGALALDEITRLLTGFTNLPLWIVIFGAIQVVTTFYGITFIRWMNVFASPVLLAMGVYMVYLMLDGADVSLGEVMSMGGENPGMPFSTAIMIFVGGWIAVVVSIHDIVKECKVDPNASREGQTKADARYATAQWLGMVPASIIFGFIGAASMVLVGEWNPVIAITEVVGGVSIPMAILFQVFVLLATWSTNPAANLLSPAYTLCSTFPRVFTFKTGVIVSAVVGLLMMPWQFAGVLNTFLNLLASALGPLAGIMISDYFLVRRRRISLHDLYRTKGIYTYWRGVNWVALAVYAVALAVSFLTPDLMFVTGLIAALLLHIPAMRWVAKTFPLFSEAESRNEDYL
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.2 23-254 232 1-22 274-456 255-273 22 183 slipknot
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4.1 19-273 255 1-18 294-456 274-293 18 163 slipknot
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3.2 20-289 270 1-2, 304-456 3-19, 290-303 2 153 slipknot
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3.2 20-303 284 1-2, 305-456 3-19, 304-304 2 152 slipknot
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4.1 33-280 248 1-18, 301-456 19-32, 281-300 18 156 slipknot
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3.2 32-300 269 1-19, 304-456 20-31, 301-303 19 153 slipknot
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3.2 30-271 242 1-22, 278-456 23-29, 272-277 22 179 slipknot
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2.3 31-259 229 1-24, 266-456 25-30, 260-265 24 191 slipknot
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2.1 49-217 169 1-25, 244-456 26-48, 218-243 25 213 slipknot
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2.1 33-311 279 1-26, 333-456 27-32, 312-332 26 124 slipknot
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2.1 57-343 287 344-456 1-29 30-56 29 112 slipknot
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1.1 52-242 191 1-37, 261-456 38-51, 243-260 37 196 slipknot
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2.1 44-301 258 1-37, 307-456 38-43, 302-306 37 150 slipknot
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1.1 54-242 189 1-51, 260-456 52-53, 243-259 51 197 slipknot
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3.1 57-242 186 1-53, 261-456 54-56, 243-260 53 196 slipknot
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2.1 55-224 170 1-49, 239-456 50-54, 225-238 49 218 slipknot
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2.1 55-314 260 1-49, 339-456 50-54, 315-338 49 118 slipknot
sequence length 456
structure length 456
publication title Molecular Mechanism of Ligand Recognition by Membrane Transport Protein, Mhp1.
pubmed doi rcsb
molecule tags Transport protein
molecule keywords HYDANTOIN TRANSPORT PROTEIN
source organism Microbacterium liquefaciens
total genus Genus: 174
ec nomenclature
pdb deposition date 2014-05-01
KnotProt deposition date 2014-08-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02133 Transp_cyt_pur Permease for cytosine/purines, uracil, thiamine, allantoin
Image from the rcsb pdb (www.rcsb.org)
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