4FY0A

Crystal structure of leut-f253a bound to l-selenomethionine from lipid bicelles
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
  • Chain breaks within knot 41 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Genus: 208
Slipknot S +31 41 +31

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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 39-264 226 265-505 1-24 25-38 24 240 slipknot
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41 13-293 281 1-12 346-505 294-345 12 160 slipknot
Chain Sequence
REHWATRLGLILAMAGNAVGLGNFLRFPVQAAENGGGAFMIPYIIAFLLVGIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVVAIYYVYIESWTLGFAIKFLVGLVPEPP---TDPDSILRPFKEFLYSYIGVPKGDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFATLSLGFGAIITYASYVRKDQDIVLSGLTAATLNEKAEVILGGSISIPAAVAFFGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLTSSIAIMQPMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFWAGTIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRYITPAFLAVLLVVWAREYIPKIMEETHWTVWITRFYIIGLFLFLTFLVFLAERRRNM
Whole chain analysis

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Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.2 9-288 280 1-8 300-502 289-299 8 203 slipknot
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4.1 13-300 288 1-12 311-502 301-310 12 192 slipknot
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4.1 9-319 311 1-8 328-502 320-327 8 175 slipknot
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3.2 13-334 322 1-12 347-502 335-346 12 156 slipknot
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3.2 15-311 297 1-7, 318-502 8-14, 312-317 7 185 slipknot
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2.1 24-432 409 1-17, 453-502 18-23, 433-452 17 50 slipknot
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2.1 31-258 228 1-18, 272-502 19-30, 259-271 18 231 slipknot
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2.1 26-272 247 1-18, 279-502 19-25, 273-278 18 224 slipknot
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2.1 36-411 376 1-18, 470-502 19-35, 412-469 18 33 slipknot
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2.1 41-354 314 1-19, 397-502 20-40, 355-396 19 106 slipknot
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2.1 41-405 365 406-502 1-19 20-40 19 96 slipknot
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1.1 29-275 247 1-21, 285-502 22-28, 276-284 21 218 slipknot
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2.1 32-270 239 1-25, 276-502 26-31, 271-275 25 227 slipknot
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3.1 34-270 237 1-31, 276-502 32-33, 271-275 31 227 slipknot
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2.1 43-278 236 1-28, 293-502 29-42, 279-292 28 210 slipknot
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1.1 40-241 202 1-30, 250-502 31-39, 242-249 30 253 slipknot
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2.1 39-397 359 1-33, 405-502 34-38, 398-404 33 98 slipknot
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3.1 41-261 221 1-34, 272-502 35-40, 262-271 34 231 slipknot
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2.1 40-271 232 1-34, 273-502 35-39, 272-272 34 230 slipknot
sequence length 505
structure length 502
publication title Substrate binds in the S1 site of the F253A mutant of LeuT, a neurotransmitter sodium symporter homologue.
pubmed doi rcsb
molecule tags Transport protein
molecule keywords Transporter
source organism Aquifex aeolicus
missing residues 128-130
total genus Genus: 208
ec nomenclature
pdb deposition date 2012-07-03
KnotProt deposition date 2014-08-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00209 SNF Sodium:neurotransmitter symporter family
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
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How to cite
KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling