4P1AA

Thallium-bound inward-facing state of the glutamate transporter homologue gltph
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 51-320 270 1-50 339-413 321-338 50 75 slipknot
Chain Sequence
YIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLCMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVATFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLCMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGRTMVNVTGDLTGTAIVAKTEGTL
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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2.1 45-313 269 1-44 344-413 314-343 44 70 slipknot
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2.1 16-358 343 1-15 368-413 359-367 15 46 slipknot
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2.1 38-356 319 1-18, 367-413 19-37, 357-366 18 47 slipknot
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2.1 54-323 270 1-46, 333-413 47-53, 324-332 46 81 slipknot
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1.1 57-330 274 1-46, 344-413 47-56, 331-343 46 70 slipknot
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2.1 55-313 259 1-47, 323-413 48-54, 314-322 47 91 slipknot
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1.1 58-330 273 1-56, 343-413 57-57, 331-342 56 71 slipknot
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1.1 61-330 270 1-57, 344-413 58-60, 331-343 57 70 slipknot
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1.1 58-316 259 1-50, 327-413 51-57, 317-326 50 87 slipknot
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1.1 59-316 258 1-57, 327-413 58-58, 317-326 57 87 slipknot
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1.1 62-329 268 1-53, 339-413 54-61, 330-338 53 75 slipknot
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1.1 62-338 277 1-60, 343-413 61-61, 339-342 60 71 slipknot
sequence length 413
structure length 413
publication title Coupled ion binding and structural transitions along the transport cycle of glutamate transporters.
pubmed doi rcsb
molecule tags Transport protein
molecule keywords GltPh
source organism Pyrococcus horikoshii
total genus Genus: 155
ec nomenclature
pdb deposition date 2014-02-25
KnotProt deposition date 2014-08-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00375 SDF Sodium:dicarboxylate symporter family
Image from the rcsb pdb (www.rcsb.org)
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