5CJLA

Crystal structure of human carbonic anhydrase ii in complex with a heteroaryl-pyrazole carboxylic acid derivative.
Knot K +31
Knot core rangeKnot core lengthKnot tails rangeSlipknot tails rangeSlipknot loops rangeN-end lengthC-end lengthType
view details
+31 26-253 228 1-25, 254-257 25 4 knot
Chain Sequence
HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
sequence length 257
structure length 257
publication title Exploration of substituted heteroaryl-pyrazole carboxylic acid derivatives as novel human carbonic anhydrase cytosolic isozymes I and II, and transmembrane tumor-associated isozymes IX and XII.
rcsb
molecule tags Lyase/lyase inhibitor
molecule keywords Carbonic anhydrase 2
source organism Homo sapiens
ec nomenclature
pdb deposition date2015-07-14
KnotProt deposition date2016-09-28
Image from the rcsb pdb (www.rcsb.org)
5CJLA
similar chains in the KnotProt database (40% sequence similarity)

 
            
               
#similar chains in the KnotProt database (40% sequence similarity)
 5CJL A; 
               
               
           

KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling