5VEOA

Murine ectonucleotide pyrophosphatase / phosphodiesterase 5 (enpp5, npp5), inactive (t72a), in complex with amp
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 9-212 204 1-8 324-374 213-323 8 51 slipknot
Chain Sequence
EQKVLVVSFDGFRWDYLYKVPTPHFHYIMKNGVHVNQVTNVFITKAYPNHYTLVTGLFAENHGIVANDMFDPILNKSFSLEHMDIYDSKFWEEATPIWITNQRAGHASGAAMWPGADVKIHDSFPTYYLPYNESVSFEDRVAKIIEWFTAKDPINLGFLYWEEPDDTGHDVGPDSPLMGSVISDVDHKLGYLIKMLKRAKLWNNVNLIVTSDHGMTQCSKQRVIELDRYLDKEHYTLIDHSPVAAILPKEGKFDEVYDALAGAHPNLTVYKKEEIPERWHYKHNDRVQPIVAVADEGWYILQNKSDDFLLGNHGYDNALAEMHPIFLAHGPAFRKNFTKEAMNSTDLYSLLCHLLNLTALPHNGSFWNVQDLLS
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
2.1 8-212 205 1-7 219-374 213-218 7 156 slipknot
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2.1 9-213 205 1-8 291-374 214-290 8 84 slipknot
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3.1 5-313 309 1-4 323-374 314-322 4 52 slipknot
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2.1 7-314 308 1-4, 320-374 5-6, 315-319 4 55 slipknot
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2.1 7-319 313 1-4, 322-374 5-6, 320-321 4 53 slipknot
view details
2.1 11-229 219 1-8, 237-374 9-10, 230-236 8 138 slipknot
sequence length 374
structure length 374
publication title A Key Tyrosine Substitution Restricts Nucleotide Hydrolysis by the Ectoenzyme NPP5.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Ectonucleotide pyrophosphatase/phosphodiesterase family memb
source organism Mus musculus
total genus Genus: 128
ec nomenclature
pdb deposition date 2017-04-05
KnotProt deposition date 2017-09-20
Image from the rcsb pdb (www.rcsb.org)
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