5Y2RA

2.5 atm co2-pressurized human carbonic anhydrase ii
Knot K +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 27-253 227 1-26, 254-257 26 4 knot
Chain Sequence
HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.1 10-256 247 1-9, 257-257 9 1 knot
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2.1 19-251 233 1-18 257-257 252-256 18 1 slipknot
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3.1 25-254 230 255-257 1-10 11-24 10 2 slipknot
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2.1 25-252 228 1-19, 255-257 20-24, 253-254 19 3 slipknot
sequence length 257
structure length 257
publication title Active-site solvent replenishment observed during human carbonic anhydrase II catalysis.
pubmed doi rcsb
molecule tags Lyase
molecule keywords Carbonic anhydrase 2
source organism Homo sapiens
total genus Genus: 75
ec nomenclature
pdb deposition date 2017-07-27
KnotProt deposition date 2018-02-14
Image from the rcsb pdb (www.rcsb.org)
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