5DOHA

Crystal structure of human carbonic anhydrase isozyme ii with 2-[(1s)-2,3-dihydro-1h-inden-1-ylamino]-3,5,6-trifluoro-4-[(2-hydroxyethyl)thio]benzenesulfonamide
Knot K +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 26-254 229 1-25, 255-258 25 4 knot
Chain Sequence
HHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.1 8-257 250 1-7, 258-258 7 1 knot
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2.1 15-252 238 1-14 258-258 253-257 14 1 slipknot
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3.1 25-255 231 256-258 1-8 9-24 8 2 slipknot
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2.1 26-252 227 1-15, 256-258 16-25, 253-255 15 3 slipknot
sequence length 258
structure length 258
publication title To be published
rcsb
molecule tags Lyase
molecule keywords Carbonic anhydrase 2
source organism Homo sapiens
total genus Genus: 78
ec nomenclature
pdb deposition date 2015-09-11
KnotProt deposition date 2016-09-28
Image from the rcsb pdb (www.rcsb.org)
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