5JAEA

Leut in the outward-oriented, na+-free return state, p21 form at ph 6.5
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
  • Chain breaks within knot 41 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Slipknot S +31 41 +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 38-262 225 263-509 1-20 21-37 20 246 slipknot
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41 14-293 280 1-13 351-509 294-350 13 159 slipknot
Chain Sequence
KREHWATRLGLILAMAGNAVGLGNFLRFPVQAAENGGGAFMIPYIIAFLLVGIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVVAIYYVYIESWTLGFAIKFLVGLVPEPP--ATDPDSILRPFKEFLYSYIGVPKGDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFTLSLGFGAIITYASYVRKDQDIVLSGLTAATLNEKAEVILGGSISIPAAVAFFGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLTSSIAIMQPMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFWAGTIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRYITPAFLAVLLVVWAREYIPKIMEETHWTVWITRFYIIGLFLFLTFLVFLAERRRNHES
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5



Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.2 13-287 275 1-12 301-507 288-300 12 207 slipknot
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4.1 6-312 307 1-5 322-507 313-321 5 186 slipknot
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4.1 7-327 321 1-6 333-507 328-332 6 175 slipknot
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3.2m 13-332 320 1-12 350-507 333-349 12 158 slipknot
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3.2 11-302 292 1-2, 311-507 3-10, 303-310 2 197 slipknot
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4.1 11-310 300 1-3, 314-507 4-10, 311-313 3 194 slipknot
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2.1 42-355 314 1-17, 399-507 18-41, 356-398 17 109 slipknot
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2.1 42-410 369 1-18, 490-507 19-41, 411-489 18 18 slipknot
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2.1 34-258 225 1-19, 274-507 20-33, 259-273 19 234 slipknot
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1.1 40-244 205 1-23, 256-507 24-39, 245-255 23 252 slipknot
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1.1 42-273 232 1-26, 292-507 27-41, 274-291 26 216 slipknot
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2.1 39-399 361 1-32, 407-507 33-38, 400-406 32 101 slipknot
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1.1 43-274 232 1-41, 291-507 42-42, 275-290 41 217 slipknot
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2.1 42-261 220 1-34, 270-507 35-41, 262-269 34 238 slipknot
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2.1 42-269 228 1-34, 274-507 35-41, 270-273 34 234 slipknot
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2.1 43-265 223 1-41, 273-507 42-42, 266-272 41 235 slipknot
sequence length 509
structure length 507
publication title A conserved leucine occupies the empty substrate site of LeuT in the Na(+)-free return state.
pubmed doi rcsb
molecule tags Membrane protein
molecule keywords Transporter
source organism Aquifex aeolicus (strain vf5)
missing residues 129-130
ec nomenclature
pdb deposition date 2016-04-12
KnotProt deposition date 2016-06-03
Image from the rcsb pdb (www.rcsb.org)
2A65A 2Q72A 3F3EA 2QEIA 2Q6HA 3GJDA 2QB4A 3F4IA 3F48A 3F3AA 3F3CA 3MPNA 3GWUA 3F4JA 3MPQA 3USPA 4MMBA 3F3DA 4MMCA 3GWVA 4MMDA 3GWWA 4MMEA 3USGA 3QS5A 5JAEA 4FXZA 4MMFA 5JAGA 3QS4A 3QS6A 3USLA 2QJUA 4MM7A 3GJCA 4FY0A 5JAFA 4MM4A 4HMKA 3USMA 3TU0A 4MM9A 4MM6A 4HODA 3TT1A 4MM5A 4MM8A 3USIA 4MMAA 3TT3A 3USJA 3USOA 3USKA
similar chains in the KnotProt database (40% sequence similarity)
4MMDB 4MMEB 5JAEB 4MMFB 3GJCB 4MM4B 4HMKB 3TT1B 3USIB 3USJB 3USOB 3USKB 3USKC 3USKD
similar chains in the pdb database (40% sequence similarity)

 
            
               
#similar chains in the KnotProt database (40% sequence similarity)
 2A65 A;  2Q72 A;  3F3E A;  2QEI A;  2Q6H A;  3GJD A;  2QB4 A;  3F4I A;  3F48 A;  3F3A A;  3F3C A;  3MPN A;  3GWU A;  3F4J A;  3MPQ A;  3USP A;  4MMB A;  3F3D A;  4MMC A;  3GWV A;  4MMD A;  3GWW A;  4MME A;  3USG A;  3QS5 A;  5JAE A;  4FXZ A;  4MMF A;  5JAG A;  3QS4 A;  3QS6 A;  3USL A;  2QJU A;  4MM7 A;  3GJC A;  4FY0 A;  5JAF A;  4MM4 A;  4HMK A;  3USM A;  3TU0 A;  4MM9 A;  4MM6 A;  4HOD A;  3TT1 A;  4MM5 A;  4MM8 A;  3USI A;  4MMA A;  3TT3 A;  3USJ A;  3USO A;  3USK A; 
               
               
           
#similar chains in the pdb database (40% sequence similarity)
 4MMD B;  4MME B;  5JAE B;  4MMF B;  3GJC B;  4MM4 B;  4HMK B;  3TT1 B;  3USI B;  3USJ B;  3USO B;  3USK B;  3USK C;  3USK D; 
           

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