5MX9A

High resolution crystal structure of the mcr-2 catalytic domain
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 28-248 221 1-27 278-324 249-277 27 47 slipknot
Chain Sequence
GPTIYHAKDAVQTTKPSERKPRLVVFVVGETARADHVQFNGYGRETFPQLAKVDGLANFSQVTSCGTSTAYSVPCMFSYLGQDDYDVDTAKYQENVLDTLDRLGVGILWRDNNSDSKGVMDKLPATQYFDYKSATNNTICNTNPYNECRDVGMLVGLDDYVSANNGKDMLIMLHQMGNHGPAYFKRYDEQFAKFTPVCEGNELAKCEHQSLINAYDNALLATDDFIAKSIDWLKTHEANYDVAMLYVSDHGESLGENGVYLHGMPNAFAPKEQRAVPAFFWSNNTTFKPTASDTVLTHDAITPTLLKLFDVTAGKVKDRAAFIQ
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5



Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
3.1 25-248 224 1-24 276-324 249-275 24 49 slipknot
view details
2.1 6-275 270 1-5 279-324 276-278 5 46 slipknot
sequence length 324
structure length 324
publication title 1.12 angstrom resolution crystal structure of the catalytic domain of the plasmid-mediated colistin resistance determinant MCR-2.
pubmed doi rcsb
molecule tags Transferase
molecule keywords Phosphatidylethanolamine transferase Mcr-2
source organism Escherichia coli
ec nomenclature
pdb deposition date 2017-01-22
KnotProt deposition date 2017-08-29
Image from the rcsb pdb (www.rcsb.org)
5MX9A 5K4PA 4KAVA 5GRRA 5YLCA 5YLFA 4KAYA 5LRMA 5YLEA 5GOVA 4TN0A 5LRNA
similar chains in the KnotProt database (40% sequence similarity)
6BNCA 6BNCB 5LRNB 6BNDA 6BNDB 4KAYB 5ZJVA 5GOVB 6BNFA 4TN0B 4TN0C 6BNEA
similar chains in the pdb database (40% sequence similarity)

 
            
               
#similar chains in the KnotProt database (40% sequence similarity)
 5MX9 A;  5K4P A;  4KAV A;  5GRR A;  5YLC A;  5YLF A;  4KAY A;  5LRM A;  5YLE A;  5GOV A;  4TN0 A; 
               
               
#similar chains, but unknotted
 5LRN A;                               
               
           
#similar chains in the pdb database (40% sequence similarity)
 6BNC A;  6BNC B;  5LRN B;  6BND A;  6BND B;  4KAY B;  5ZJV A;  5GOV B;  6BNF A;  4TN0 B;  4TN0 C;  6BNE A; 
           

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