5T75A

Human carbonic anhydrase ii g132c_c206s double mutant in complex with sa-2
Knot K +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 26-253 228 1-25, 254-257 25 4 knot
Chain Sequence
HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFCKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLESVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.1 24-256 233 1-23, 257-257 23 1 knot
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2.1 25-251 227 1-24 257-257 252-256 24 1 slipknot
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2.1 28-255 228 256-257 1-25 26-27 25 1 slipknot
sequence length 257
structure length 257
publication title A rational approach for the optical control of carbonic anhydrase II activity
rcsb
molecule tags Lyase
molecule keywords Carbonic anhydrase 2
source organism Homo sapiens
total genus Genus: 77
ec nomenclature
pdb deposition date 2016-09-02
KnotProt deposition date 2017-09-14
Image from the rcsb pdb (www.rcsb.org)
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