5TOOA

Crystal structure of alkaline phosphatase pafa t79s, n100a, k162a, r164a mutant
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 14-329 316 1-13 474-522 330-473 13 49 slipknot
Chain Sequence
NAVPRPKLVVGLVVDQMRWDYLYRYYSKYGEGGFKRMLNTGYSLNNVHIDYVPTVSAIGHTSIFTGSVPSIHGIAGADWYDKELGKSVYCTSDETVQPVGTTSNSVGQHSPRNLWSTTVTDQLGLATNFTSKVVGVSLADAASILPAGHNPTGAFWFDDTTGKFITSTYYTKELPKWVNDFNNKNVPAQLVANGWNTLLPINQYTESSEDNVEWEGLLGSKKTPTFPYTDLAKDYEAKKGLIRTTPFGNTLTLQMADAAIDGNQMGVDDITDFLTVNLASTDYVGHNFGPNSIEVEDTYLRLDRDLADFFNNLDKKVGKGNYLVFLSADHGAAHSVGFMQAHKMPTGFF---MKKEMNAKLKQKFGADNIIAAAMNYQVYFDRKVLADSKLELDDVRDYVMTELKKEPSVLYVLSTDEIWESSIPEPIKSRVINGYNWKRSGDIQIISKDGYLSSKK--GTTHSVWNSYDSHIPLLFMGWGIKQGESNQPYHMTDIAPTVSSLLKIQFPSGAVGKPITEVIG
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
3.1 7-329 323 1-6 335-517 330-334 6 183 slipknot
view details
3.1 13-331 319 1-12 467-517 332-466 12 51 slipknot
view details
2.1 7-466 460 1-6 471-517 467-470 6 47 slipknot
view details
2.1 14-422 409 1-12, 429-517 13-13, 423-428 12 89 slipknot
missing residues 350-352, 455-456
publication title Differential Catalytic Promiscuity of the Alkaline Phosphatase Superfamily Bimetallo Core Reveals Mechanistic Features Underlying Enzyme Evolution
doi rcsb
structure length 517
molecule tags Hydrolase
source organism Elizabethkingia meningoseptica
sequence length 522
molecule keywords Alkaline phosphatase PafA
ec nomenclature
pdb deposition date 2016-10-18
KnotProt deposition date 2017-11-01
Image from the rcsb pdb (www.rcsb.org)
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