5UDYA

Human alkaline sphingomyelinase (alk-smase, enpp7, npp7)
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 9-217 209 1-8 335-388 218-334 8 54 slipknot
Chain Sequence
QNKLLLVSFDGFRWNYDQDVDTPNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGKYIENHGVVHNMYYNTTSKVKLPYHATLGIQRWWDNGSVPIWITAQRQGLRAGSFFYPGGNVTYQGVAVTRSRKEGIAHNYKNETEWRANIDTVMAWFTEEDLDLVTLYFGEPDSTGHRYGPESPERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHGMTTVDKRAGDLVEFHKFPNFTFRDIEFELLDYGPNGMLLPKEGRLEKVYDALKDAHPKLHVYKKEAFPEAFHYANNPRVTPLLMYSDLGYVIHGRINVQFNNGEHGFDNKDMDMKTIFRAVGPSFRAGLEVEPFESVHVYELMCRLLGIVPEANDGHLATLLPMLHTES
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5



Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
3.1 5-217 213 1-4 222-388 218-221 4 167 slipknot
view details
3.1 8-221 214 1-7 252-388 222-251 7 137 slipknot
view details
3.1 6-254 249 1-5 278-388 255-277 5 111 slipknot
view details
3.1 8-278 271 1-7 323-388 279-322 7 66 slipknot
view details
3.1 7-256 250 1-5, 259-388 6-6, 257-258 5 130 slipknot
view details
2.1 7-323 317 1-2, 331-388 3-6, 324-330 2 58 slipknot
view details
3.1 9-283 275 1-7, 289-388 8-8, 284-288 7 100 slipknot
sequence length 388
structure length 388
publication title Crystal Structure of the Human Alkaline Sphingomyelinase Provides Insights into Substrate Recognition.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Ectonucleotide pyrophosphatase/phosphodiesterase family member 7
source organism Homo sapiens
ec nomenclature
pdb deposition date 2016-12-28
KnotProt deposition date 2017-03-27
Image from the rcsb pdb (www.rcsb.org)
5TCDA 5UDYA
similar chains in the KnotProt database (40% sequence similarity)

 
            
               
#similar chains in the KnotProt database (40% sequence similarity)
 5TCD A;  5UDY A; 
               
               
           

KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling