K +31
|
K 3x +31
|
|
6y74A
|
X-ray crystal structure of human carbonic anhydrase ix catalytic domain.
|
K +31
|
K 3x +31
|
|
6ymaA
|
Microed structure of acetazolamide-bound human carbonic anhydrase ii
|
S +31
|
S 3x +31
|
|
6ymbA
|
Microed structure of human carbonic anhydrase ii
|
S +31
|
S 3x +31
|
|
6ufbA
|
Carbonic anhydrase 2 with inhibitor (2z)-2-benzylidene-3-oxo-n-(4-sulfamoylphenyl)butanamide (11a/d1)
|
S +31
|
S 3x +31
|
|
6ufcA
|
Carbonic anhydrase 2 with inhibitor (2z)-2-[(4-methoxyphenyl)methylidene]-3-oxo-n-(4-sulfamoylphenyl)butanamide (11d/d4)
|
S +31
|
S 3x +31
|
|
6ufdA
|
Carbonic anhydrase 2 with inhibitor (2z)-3-oxo-n-(4-sulfamoylphenyl)-2-[(thiophen-2-yl)methylidene]butanamide (11g/d7)
|
S +31
|
S 3x +31
|
|
6klzA
|
Human carbonic anhydrase ii v143i variant 00 atm co2
|
S +31
|
S 3x +31
|
|
6km0A
|
Human carbonic anhydrase ii v143i variant 07 atm co2
|
K +31
|
K 3x +31
|
|
6km1A
|
Human carbonic anhydrase ii v143i variant 13 atm co2
|
K +31
|
K 3x +31
|
|
6km2A
|
Human carbonic anhydrase ii v143i variant 15 atm co2
|
K +31
|
K 3x +31
|
|
6km3A
|
Human carbonic anhydrase ii native 00 atm co2
|
S +31
|
S 3x +31
|
|
6km4A
|
Human carbonic anhydrase ii native 07 atm co2
|
K +31
|
K 3x +31
|
|
6km5A
|
Human carbonic anhydrase ii native 13 atm co2
|
S +31
|
S 3x +31
|
|
6km6A
|
Human carbonic anhydrase ii native 15 atm co2
|
S +31
|
S 3x +31
|
|
6wq4A
|
Carbonic anhydrase ii complexed with 2-((2-cyanoethyl)(phenethyl)amino)-n-phenethyl-n-(4-sulfamoylphenethyl)acetamide
|
K +31
|
K 3x +31
|
|
6wq7A
|
Carbonic anhydrase ii complexed with 2-((3-aminopropyl)(phenethyl)amino)-n-(4-fluorobenzyl)-n-(4-sulfamoylphenethyl)acetamide
|
S +31
|
S 3x +31
|
|
6wq8A
|
Carbonic anhydrase ii complexed with 3-((2-((furan-2-ylmethyl)(4-sulfamoylphenethyl)amino)-2-oxoethyl)(phenethyl)amino)propanoic acid
|
S +31
|
S 3x +31
|
|
6wq9A
|
Carbonic anhydrase ii complexed with 3-((2-((naphthalen-2-ylmethyl)(4-sulfamoylphenethyl)amino)-2-oxoethyl)(phenethyl)amino)propanoic acid
|
S +31
|
S 3x +31
|
|
6rmxA
|
Human carbonic anhydrase ii mutant t199v bound by 2-[(1s)-2,3-dihydro-1h-inden-1-ylamino]-3,5,6-trifluoro-4-[(2-hydroxyethyl)thio]benzenesulfonamide
|
S +31
|
S 3x +31
|
|
6t7uA
|
Carborane inhibitor of carbonic anhydrase ix
|
S +31
|
S 3x +31
|
|
6t9zA
|
Nidocarborane inhibitor of carbonic anhydrase ix
|
K +31
|
K 3x +31
|
|
6otiA
|
Carbonic anhydrase ix mimic complexed with ureic benzene sulfonamide mb9-561b
|
S +31
|
S 3x +31
|
|
6otkA
|
Carbonic anhydrase ix mimic complexed with ureido benzene sulfonamide mb10-596b
|
K +31
|
K 3x +31
|
|
6otmA
|
Carbonic anhydrase ix mimic complexed with ureic benzene sulfonamide mb10-586b
|
S +31
|
S 3x +31
|
|
6otoA
|
Carbonic anhydrase ii complexed with ureic benzene sulfonamide mb9-561b
|
S +31
|
S 3x +31
|
|
6otpA
|
Carbonic anhydrase ii complexed with ureic benzene sulfonamide mb10-586b
|
S +31
|
S 3x +31
|
|
6otqA
|
Carbonic anhydrase ii complexed with ureic benzene sulfonamide mb10-596b
|
S +31
|
S 3x +31
|
|
6oubA
|
Carbonic anhydrase ii complexed with benzene sulfonamide mb11-694b
|
S +31
|
S 3x +31
|
|
6oudA
|
Carbonic anhydrase ix mimic complexed with benzene sulfonamide mb11-694b
|
K +31
|
K 3x +31
|
|
6oueA
|
Carbonic anhydrase ii complexed with benzene sulfonamide mb11-707a
|
S +31
|
S 3x +31
|
|
6oufA
|
Carbonic anhydrase ix mimic complexed with benzene sulfonamide mb11-707a
|
S +31
|
S 3x +31
|
|
6ouhA
|
Carbonic anhydrase ii mimic complexed with benzene sulfonamide mb11-710a
|
S +31
|
S 3x +31
|
|
6ouiA
|
Carbonic anhydrase ix mimic complexed with benzene sulfonamide mb11-710a
|
S +31
|
S 3x +31
|
|
6oujA
|
Carbonic anhydrase ii complexed with benzene sulfonamide mb11-689a
|
S +31
|
S 3x +31
|
|
6oukA
|
Carbonic anhydrase ii complexed with benzene sulfonamide mb10-580b
|
S +31
|
S 3x +31
|
|
6oumA
|
Carbonic anhydrase ix mimic complexed with benzene sulfonamide mb10-580b
|
S +31
|
S 3x +31
|
|
6rg3A
|
Crystal structure of human carbonic anhydrase ii in complex with (r)-4-(2-benzylpiperazin-1-yl)benzenesulfonamide
|
K +31
|
K 3x +31
|
|
6rg4A
|
Crystal structure of human carbonic anhydrase ii in complex with (r)-4-(2-benzyl-4-methylpiperazin-1-yl)benzenesulfonamide
|
K +31
|
K 3x +31
|
|
6rhjA
|
Crystal structure of human carbonic anhydrase isozyme ii with 4-(4-benzyl-1,4-diazepane-1-carbonyl)benzenesulfonamide
|
S +31
|
S 3x +31
|
|
6rhkA
|
The crystal structure of human carbonic anhydrase ii in complex with 4-(3-benzylimidazolidine-1-carbonyl)benzenesulfonamide
|
S +31
|
S 3x +31
|
|
6rmyA
|
Human carbonic anhydrase ii mutant t199v bound by 3-(cyclooctylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide
|
K +31
|
K 3x +31
|
|
6rofA
|
Human carbonic anhydrase ii mutant t199v bound by 2-(cyclooctylamino)-3,5,6-trifluoro-4-[(2-hydroxyethyl)thio]benzenesulfonamide
|
S +31
|
S 3x +31
|
|
6rzxA
|
Carbonic anhydrase caix mimic in complex with inhibitor fbsa
|
S +31
|
S 3x +31
|
|
6s03A
|
Carbonic anhydrase caix mimic in complex with inhibitor i39lt379
|
S +31
|
S 3x +31
|
|
6sdsA
|
Human carbonic anhydrase ii in complex with a sulfonamide inhibitor
|
S +31
|
S 4x +31
|
|
6sdtA
|
Human carbonic anhydrase vii in complex with a sulfonamide inhibitor
|
K +31
|
K 3x +31
|
|
6ux1A
|
Carbonic anhydrase ii complexed with salicylic acid
|
S +31
|
S 3x +31
|
|
6r6jA
|
Crystal structure of human carbonic anhydrase isozyme ii with 2-(benzenesulfonyl)-4-chloro-n-(2-hydroxyethyl)-5-sulfamoyl-benzamide
|
K +31
|
K 3x +31
|
|
6r6yA
|
Crystal structure of human carbonic anhydrase isozyme xii with 4-chloro-2-cyclohexylsulfanyl-n-(2-hydroxyethyl)-5-sulfamoyl-benzamide
|
S +31
|
S 3x +31
|
|
6r71A
|
Crystal structure of human carbonic anhydrase isozyme xii with 2-(benzenesulfonyl)-4-chloro-n-(2-hydroxyethyl)-5-sulfamoyl-benzamide
|
K +31
|
K 3x +31
|
|
6vj3A
|
Carbonic anhydrase ii in complex with pyrimidine-based inhibitor
|
K +31
|
K 3x +31
|
|
6ugnA
|
Human carbonic anhydrase 2 complexed with sb4-205
|
S +31
|
S 3x +31
|
|
6ugoA
|
Human carbonic anhydrase ix-mimic complexed with sb4-205
|
S +31
|
S 3x +31
|
|
6ugpA
|
Human carbonic anhydrase 2 complexed with sb4-206
|
S +31
|
S 3x +31
|
|
6ugqA
|
Human carbonic anhydrase ix-mimic complexed with sb4-206
|
S +31
|
S 3x +31
|
|
6ugrA
|
Human carbonic anhydrase 2 complexed with sb4-208
|
S +31
|
S 3x +31
|
|
6ugzA
|
Human carbonic anhydrase ix-mimic complexed with sb4-208
|
S +31
|
S 3x +31
|
|
6uh0A
|
Human carbonic anhydrase 2 in complex with sb4-202
|
S +31
|
S 7x +31
|
|
6pdvA
|
Cu-carbonic anhydrase ii, a nitrite reductase
|
S +31
|
|
|
6peaA
|
High resolution apo carbonic anhydrase ii
|
K +31
|
K 3x +31
|
|
6qngA
|
Three dimensional structure of human carbonic anhydrase xii in complex with benzenesulfonamide
|
K +31
|
K 3x +31
|
|
6qnlA
|
Three dimensional structure of human carbonic anhydrase xii in complex with benzenesulfonamide
|
S +31
|
S 3x +31
|
|
6r6fA
|
Crystal structure of human carbonic anhydrase isozyme ii with 4-chloro-2-cyclohexylsulfanyl-n-(2-hydroxyethyl)-5-sulfamoyl-benzamide
|
S +31
|
S 3x +31
|
|
6qn0A
|
Three dimensional structure of human carbonic anhydrase xii in complex with benzenesulfonamide
|
S +31
|
S 3x +31
|
|
6qn2A
|
Three dimensional structure of human carbonic anhydrase ix in complex with benzenesulfonamide
|
K +31
|
K 3x +31
|
|
6qn5A
|
Three dimensional structure of human carbonic anhydrase ix in complex with benzenesulfonamide
|
S +31
|
S 3x +31
|
|
6qn6A
|
Three dimensional structure of human carbonic anhydrase ix in complex with benzenesulfonamide
|
S +31
|
S 3x +31
|
|
6u4qA
|
Carbonic anhydrase 2 in complex with sb4197
|
S +31
|
S 3x +31
|
|
6u4tA
|
Carbonic anhydrase 9 in complex with sb4197
|
S +31
|
S 3x +31
|
|
6nlvA
|
Selective inhibition of carbonic anhydrase ix activity, using compound slc-149, displays limited anticancer effects in breast cancer cell lines
|
S +31
|
S 3x +31
|
|
6nm0A
|
Selective inhibition of carbonic anhydrase ix activity, using compound slc-149, displays limited anticancer effects in breast cancer cell lines
|
K +31
|
K 3x +31
|
|
6i0jA
|
Crystal structure of human carbonic anhydrase i in complex with the 4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenyl sulfamate inhibitor
|
S +31
|
S 3x +31
|
|
6i0lA
|
Crystal structure of human carbonic anhydrase i in complex with the 1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-(4-sulfamoylphenyl)ethyl]urea inhibitor
|
K +31
|
K 31x +31
|
|
6i0wA
|
Human carbonic anhydrase ii in complex with 4-methoxybenzenesulfonamide
|
S +31
|
S 15x +31
|
|
6i1uA
|
Human carbonic anhydrase ii in complex with 4-ethoxybenzenesulfonamide
|
S +31
|
S 19x +31
|
|
6i2fA
|
Human carbonic anhydrase ii in complex with 4-propoxybenzenesulfonamide
|
K +31
|
K 3x +31
|
|
6qqmA
|
Crystal structure of the alpha carbonic anhydrase from schistosoma mansoni
|
S +31
|
S 15x +31
|
|
6hxdA
|
Human carbonic anhydrase ii in complex with 4-butylbenzenesulfonamide
|
K +31
|
K 15x +31
|
|
6hr3A
|
Human carbonic anhydrase ii in complex with 4-propylbenzenesulfonamide
|
K +31
|
K 3x +31
|
4
|
6nj2A
|
Thermostable carbonic anhydrase ii variant with tetrazine 2.0 at site 186
|
S +31
|
S 3x +31
|
4
|
6nj3A
|
Thermostable variant of human carbonic anhydrase with ordered tetrazine 2.0 at site 233
|
K +31
|
K 3x +31
|
4
|
6nj4A
|
Thermostable variant of human carbonic anhydrase with disordered tetrazine 2.0 reacted with strained trans-cyclooctene at site 233
|
K +31
|
K 3x +31
|
3
|
6nj5A
|
Thermostable variant of human carbonic anhydrase ii with disordered tetrazine 2.0 at site 233
|
S +31
|
S 3x +31
|
4
|
6nj6A
|
Thermostable variant of human carbonic anhydrase with tetrazine 2.0 at site 186 reacted with stco in crystallo
|
S +31
|
S 3x +31
|
|
6ql1A
|
Crystal structure of chimeric carbonic anhydrase vi with 4-[(4,6-dimethylpyrimidin-2-yl)thio]-2,3,5,6-tetrafluorobenzenesulfonamide
|
S +31
|
S 3x +31
|
|
6ql2A
|
Crystal structure of chimeric carbonic anhydrase vi with ethoxzolamide.
|
K +31
|
K 3x +31
|
|
6ql3A
|
Crystal structure of chimeric carbonic anhydrase vi with 3-(cyclooctylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide
|
K +31
|
K 3x +31
|
|
6rqnA
|
X-ray crystal structure of protiated (h) small monoclinic unit cell ca ix sv.
|
K +31
|
K 3x +31
|
|
6rqqA
|
X-ray crystal structure of protiated (h) large monoclinic unit cell ca ix sv.
|
S +31
|
S 3x +31
|
|
6hd2A
|
Active-site conformational dynamics of carbonic anhydrase ii under native conditions: an nmr perspective
|
S +31
|
S 1x +31
|
|
12caA
|
Altering the mouth of a hydrophobic pocket. structure and kinetics of human carbonic anhydrase ii mutants at residue val-121
|
S +31
|
S 3x +31
|
|
1azmA
|
Drug-protein interactions: structure of sulfonamide drug complexed with human carbonic anhydrase i
|
S +31
|
S 23x +31
|
|
1bnnA
|
Carbonic anhydrase ii inhibitor
|
S +31
|
S 7x +31
|
|
1bv3A
|
Human carbonic anhydrase ii complexed with urea
|
K +31
|
K 3x +31
|
|
1cakA
|
Structural analysis of the zinc hydroxide-thr 199-glu 106 hydrogen bonding network in human carbonic anhydrase ii
|
S +31
|
S 3x +31
|
|
1rzbA
|
X-ray analysis of metal substituted human carbonic anhydrase ii derivatives
|
S +31
|
S 3x +31
|
|
1ttmA
|
Human carbonic anhydrase ii complexed with 667-coumate
|
S +31
|
S 3x +31
|
|
4qizA
|
Crystal structure of human carbonic anhydrase isozyme xiii with inhibitor
|
S +31
|
S 3x +31
|
|
4qsjA
|
Crystal structure of human carbonic anhydrase isozyme xiii with 2-chloro-4-{[(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio]acetyl}benzenesulfonamide
|
S +31
|
S 3x +31
|
|
4yglA
|
Naclo4--interactions between hofmeister anions and the binding pocket of a protein
|
K +31
|
K 3x +31
|
|
5fl5A
|
Three dimensional structure of human carbonic anhydrase ix in complex with 5-(1-(4-methoxyphenyl)-1h-1,2,3-triazol-4-yl)thiophene-2- sulfonamide
|
S +31
|
S 11x +31
|
|
1bn1A
|
Carbonic anhydrase ii inhibitor
|
S +31
|
S 11x +31
|
|
1bn3A
|
Carbonic anhydrase ii inhibitor
|
S +31
|
S 11x +31
|
|
1bn4A
|
Carbonic anhydrase ii inhibitor
|
S +31
|
S 7x +31
|
|
1bnqA
|
Carbonic anhydrase ii inhibitor
|
K +31
|
K 3x +31
|
|
1caoA
|
Crystallographic studies of the binding of protonated and unprotonated inhibitors to carbonic anhydrase using hydrogen sulphide and nitrate anions
|
S +31
|
S 5x +31
|
|
1ccsA
|
Structure-assisted redesign of a protein-zinc binding site with femtomolar affinity
|
S +31
|
S 5x +31
|
|
1cniA
|
X-ray crystallographic studies of engineered hydrogen bond networks in a protein-zinc binding site
|
K +31
|
K 5x +31
|
|
1cnjA
|
X-ray crystallographic studies of engineered hydrogen bond networks in a protein-zinc binding site
|
S +31
|
S 3x +31
|
|
1cvbA
|
Structural and functional importance of a conserved hydrogen bond network in human carbonic anhydrase ii
|
S +31
|
S 1x +31
|
|
1cveA
|
Structural consequences of redesigning a protein-zinc binding site
|
S +31
|
S 11x +31
|
|
1fqlA
|
X-ray crystal structure of zinc-bound f95m/w97v carbonic anhydrase (caii) variant
|
K +31
|
K 3x +31
|
|
1fsqA
|
X-ray crystal structure of cobalt-bound f93s/f95l/w97m carbonic anhydrase (caii) variant
|
S +31
|
S 7x +31
|
|
1g3zA
|
Carbonic anhydrase ii (f131v)
|
S +31
|
S 7x +31
|
|
1g46A
|
Carbonic anhydrase ii (f131v) complexed with 4-(aminosulfonyl)-n-[(2,3-difluorophenyl)methyl]-benzamide
|
S +31
|
S 3x +31
|
|
1hcbA
|
Enzyme-substrate interactions: structure of human carbonic anhydrase i complexed with bicarbonate
|
S +31
|
S 11x +31
|
|
1heaA
|
Carbonic anhydrase ii (carbonate dehydratase) (hca ii) (e.c.4.2.1.1) mutant with leu 198 replaced by arg (l198r)
|
S +31
|
S 3x +31
|
|
1hugA
|
Differences in anionic inhibition of human carbonic anhydrase i revealed from the structures of iodide and gold cyanide inhibitor complexes
|
S +31
|
S 3x +31
|
|
1huhA
|
Differences in anionic inhibition of human carbonic anhydrase i revealed from the structures of iodide and gold cyanide inhibitor complexes
|
S +31
|
S 15x +31
|
|
1i9nA
|
Carbonic anhydrase ii (f131v) complexed with 4-(aminosulfonyl)-n-[(2,5-difluorophenyl)methyl]-benzamide
|
S +31
|
S 23x +31
|
|
1if4A
|
Carbonic anhydrase ii complexed with 4-fluorobenzenesulfonamide
|
S +31
|
S 15x +31
|
|
1if6A
|
Carbonic anhydrase ii complexed with 3,5-difluorobenzenesulfonamide
|
S +31
|
S 3x +31
|
|
1j9wA
|
Solution structure of the cai michigan 1 variant
|
S +31
|
S 3x +31
|
|
1lgdA
|
Crystal structure analysis of hca ii mutant t199p in complex with bicarbonate
|
S +31
|
S 3x +31
|
|
1rj5A
|
Crystal structure of the extracellular domain of murine carbonic anhydrase xiv
|
S +31
|
S 3x +31
|
|
1th9A
|
Effect of shuttle location and ph environment on h+ transfer in human carbonic anhydrase ii
|
K +31
|
K 3x +31
|
|
1ugdA
|
Human carbonic anhydrase ii[hcaii] (e.c.4.2.1.1) mutant with ala 65 replaced by ser (a65s)
|
S +31
|
S 11x +31
|
|
1yddA
|
Structural basis of inhibitor affinity to variants of human carbonic anhydrase ii
|
S +31
|
S 3x +31
|
|
1yo0A
|
Proton transfer from his200 in human carbonic anhydrase ii
|
K +31
|
K 3x +31
|
|
1z97A
|
Human carbonic anhydrase iii: structural and kinetic study of catalysis and proton transfer.
|
K +31
|
K 7x +31
|
|
1ze8A
|
Carbonic anhydrase ii in complex with a membrane-impermeant sulfonamide inhibitor
|
S +31
|
S 3x +31
|
|
1zscA
|
Carbonic anhydrase ii mutant e117q, holo form
|
S +31
|
S 3x +31
|
|
2cbaA
|
Structure of native and apo carbonic anhydrase ii and some of its anion-ligand complexes
|
S +31
|
S 3x +31
|
|
2cbdA
|
Structure of native and apo carbonic anhydrase ii and some of its anion-ligand complexes
|
S +31
|
S 3x +31
|
|
2eu3A
|
Human carbonic anhydrase ii in complex with novel inhibitors
|
S +31
|
S 3x +31
|
|
2f14A
|
Tne crystal structure of the human carbonic anhydrase ii in complex with a fluorescent inhibitor
|
K +31
|
K 3x +31
|
|
2fnnA
|
Activation of human carbonic anhydrase ii by exogenous proton donors
|
S +31
|
S 3x +31
|
4
|
2foqA
|
Human carbonic anhydrase ii complexed with two-prong inhibitors
|
S +31
|
S 3x +31
|
|
2fw4A
|
Carbonic anhydrase activators. the first x-ray crystallographic study of an activator of isoform i, structure with l-histidine.
|
S +31
|
S 11x +31
|
|
2gd8A
|
Crystal structure analysis of the human carbonic anhydrase ii in complex with a 2-substituted estradiol bis-sulfamate
|
S +31
|
S 1x +31
|
|
2hfwA
|
Structural and kinetic analysis of proton shuttle residues in the active site of human carbonic anhydrase iii
|
S +31
|
S 7x +31
|
|
2hocA
|
Crystal structure of the human carbonic anhydrase ii in complex with the 5-(4-amino-3-chloro-5-fluorophenylsulfonamido)-1,3,4-thiadiazole-2-sulfonamide inhibitor
|
S +31
|
S 3x +31
|
4
|
2nngA
|
Structure of inhibitor binding to carbonic anhydrase ii
|
K +31
|
K 3x +31
|
4
|
2nnoA
|
Structure of inhibitor binding to carbonic anhydrase ii
|
S +31
|
S 3x +31
|
4
|
2nnvA
|
Structure of inhibitor binding to carbonic anhydrase ii
|
K +31
|
K 3x +31
|
|
2nwoA
|
Structural and kinetic effect of hydrophobic mutations in the active site of human carbonic anhydrase ii
|
S +31
|
S 3x +31
|
|
2wehA
|
Thermodynamic optimisation of carbonic anhydrase fragment inhibitors
|
S +31
|
S 3x +31
|
4
|
2x7sA
|
Structures of human carbonic anhydrase ii inhibitor complexes reveal a second binding site for steroidal and non-steroidal inhibitors.
|
S +31
|
S 3x +31
|
|
3bl1A
|
Carbonic anhydrase inhibitors. sulfonamide diuretics revisited old leads for new applications
|
S +31
|
S 3x +31
|
|
3d92A
|
Human carbonic anhydrase ii bound with substrate carbon dioxide
|