K 3.1, 2.1
|
|
2fnnA
|
Activation of human carbonic anhydrase ii by exogenous proton donors
|
K 3.1, 2.1
|
4
|
5jdfA
|
Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchanger ncx_mj soaked with 2.5 mm na+ and 1mm ca2+
|
K 3.1, 2.1
|
|
3mnjA
|
Human carbonic anhydrase ii mutant k170e
|
K 3.1, 2.1
|
|
3hljA
|
Crystal structure of human carbonic anhydrase isozyme ii with 3-methylthiobenzimidazo[1,2-c][1,2,3]thiadiazol-7-sulfonamide
|
K 3.1, 2.1
|
|
3oikA
|
Human carbonic anhydrase ii mutant a65s, n67q (ca ix mimic) bound by 2-ethylestradiol 3,17-o,o-bis-sulfamate
|
K 3.1, 2.1
|
|
3hknA
|
Human carbonic anhydrase ii in complex with (2,3,4,6-tetra-o-acetyl-beta-d-galactopyranosyl) -(1-4)-1,2,3,6-tetra-o-acetyl-1-thio-beta-d-glucopyranosylsulfonamide
|
K 3.1, 2.1
|
|
3u3aX
|
Structure of human carbonic anhydrase ii v143i
|
K 3.1, 2.1
|
|
4qk3A
|
Structural and catalytic effects of proline substitution and surface loop deletion in the extended active site of human carbonic anhydrase ii - [delta]230-240
|
K 3.1, 2.1
|
|
4kp5A
|
Crystal structure of catalytic domain of human carbonic anhydrase isozyme xii with 2-chloro-4-[(pyrimidin-2-ylsulfanyl)acetyl]benzenesulfonamide
|
K 3.1, 2.1
|
|
5jepB
|
Human carbonic anhydrase ii (t199s) complexed with benzo[d]thiazole-2-sulfonamide
|
K 3.1, 2.1
|
|
4rn4A
|
Human carbonic anhydrases ii in complex with a acetazolamide derivative comprising one hydrophobic and one hydrophilic tail moiety
|
K 3.1, 2.1
|
|
4z1eA
|
Carbonic anhydrase inhibitors: design and synthesis of new heteroaryl-n-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms (hca vii, hca ix, and hca xiv)
|
K 3.1, 2.1
|
|
5eh5A
|
Human carbonic anhydrase ii in complex with ligand
|
K 3.1, 2.1
|
|
4xe1A
|
Human carbonic anhydrase ii in complex with 6-sulfamoyl-saccharin
|
K 3.1, 2.1
|
|
5ekhA
|
Human carbonic anhydrase ii complexed with a two-faced guest
|
K 3.1, 2.1
|
|
1bn3A
|
Carbonic anhydrase ii inhibitor
|
K 3.1, 2.1
|
|
1zscA
|
Carbonic anhydrase ii mutant e117q, holo form
|
K 3.1, 2.1
|
|
2vvbX
|
Human carbonic anhydrase ii in complex with bicarbonate
|
K 3.1, 2.1
|
|
3mnkA
|
Human carbonic anhydrase ii mutant k170h
|
K 3.1, 2.1
|
|
1g3zA
|
Carbonic anhydrase ii (f131v)
|
K 3.1, 2.1
|
2
|
2nnvA
|
Structure of inhibitor binding to carbonic anhydrase ii
|
K 3.1, 2.1
|
|
3dc9A
|
Use of carbonic anhydrase ii, ix active-site mimic, for the purpose of screening inhibitors for possible anti-cancer properties
|
K 3.1, 2.1
|
|
3dazA
|
Use of carbonic anhydrase ii, ix active-site mimic, for the purpose of screening inhibitors for possible anti-cancer properties
|
K 3.1, 2.1
|
|
2cbaA
|
Structure of native and apo carbonic anhydrase ii and some of its anion-ligand complexes
|
K 3.1, 2.1
|
2
|
3s72B
|
The origin of the hydrophobic effect in the molecular recognition of arylsulfonamides by carbonic anhydrase
|
K 3.1, 2.1
|
|
2cbdA
|
Structure of native and apo carbonic anhydrase ii and some of its anion-ligand complexes
|
K 3.1, 2.1
|
|
3nj9A
|
Crystal structure of carbonic anhydrase ii in complex with a nir inhibitor
|
K 3.1, 2.1
|
|
4e3hA
|
Nucleophile recognition as an alternative inhibition mode for benzoic acid based carbonic anhydrase inhibitors
|
K 3.1, 2.1
|
|
4ca2A
|
Engineering the hydrophobic pocket of carbonic anhydrase ii
|
K 3.1, 2.1
|
|
4fptA
|
Carbonic anhydrase ii in complex with ethyl (2z,4r)-2-(sulfamoylimino)-1,3-thiazolidine-4-carboxylate
|
K 3.1, 2.1
|
|
3r17B
|
Hcarbonic anhydrase ii bound to n-(2-fluoro.4-sulfamoylphenyl)-2-(thiophen-2-yl) acetamide
|
K 3.1, 2.1
|
|
4zwzA
|
Engineered carbonic anhydrase ix mimic in complex with a glucosyl sulfamate inhibitor
|
K 3.1, 2.1
|
|
4q07A
|
Crystal structure of chimeric carbonic anhydrase ix with inhibitor
|
K 3.1, 2.1
|
|
5g01A
|
An unusual natural product primary sulfonamide: synthesis, carbonic anhydrase inhibition and protein x-ray structure of psammaplin c
|
K 3.1, 2.1
|
|
4mdlA
|
Meta carborane carbonic anhydrase inhibitor
|
K 3.1, 2.1
|
2
|
5tt3A
|
Crystal structure of the complex of helicobacter pylori alpha-carbonic anhydrase with ethoxzolamide
|
K 3.1, 2.1
|
|
5umcA
|
Synthesis of novel seleno ureido containing compounds as slc-0111 analogs. investigations on carbonic anhydrases activity, glutathione peroxidase and x-ray crystallography
|
K 3.1, 2.1
|
|
4q09A
|
Crystal structure of chimeric carbonic anhydrase xii with inhibitor
|
K 3.1, 2.1
|
|
1g46A
|
Carbonic anhydrase ii (f131v) complexed with 4-(aminosulfonyl)-n-[(2,3-difluorophenyl)methyl]-benzamide
|
K 3.1, 2.1
|
|
5ogpA
|
Metalacarborane inhibitors of carbonic anhydrase ix
|
K 3.1, 2.1
|
|
1if6A
|
Carbonic anhydrase ii complexed with 3,5-difluorobenzenesulfonamide
|
K 3.1, 2.1
|
|
6ekiA
|
Structure of a hyperthermostable carbonic anhydrase identified from an active hydrothermal vent chimney
|
K 3.1, 2.1
|
|
3igpA
|
Structure of inhibitor binding to carbonic anhydrase ii
|
K 3.1, 2.1
|
|
5fnhA
|
Native state mass spectrometry, surface plasmon resonance and x-ray crystallography correlate strongly as a fragment screening combination
|
K 3.1, 2.1
|
|
3w6hA
|
Crystal structure of 19f probe-labeled hcai in complex with acetazolamide
|
K 3.1, 2.1
|
|
5cluA
|
The crystal structure of the complex of hcaii with a saccharine derivative
|
K 3.1, 2.1
|
|
1i9nA
|
Carbonic anhydrase ii (f131v) complexed with 4-(aminosulfonyl)-n-[(2,5-difluorophenyl)methyl]-benzamide
|
K 3.1, 2.1
|
|
3mhcA
|
Crystal structure of human cabonic anhydrase ii in adduct with an adamantyl analogue of acetazolamide in a novel hydrophobic binding pocket
|
K 3.1, 2.1
|
|
5flsA
|
Native state mass spectrometry, surface plasmon resonance and x-ray crystallography correlate strongly as a fragment screening combination
|
K 3.1, 2.1
|
|
1cnjA
|
X-ray crystallographic studies of engineered hydrogen bond networks in a protein-zinc binding site
|
K 3.1, 2.1
|
|
1if4A
|
Carbonic anhydrase ii complexed with 4-fluorobenzenesulfonamide
|
K 3.1, 2.1
|
|
4pyyA
|
Crystal structure of human carbonic anhydrase isozyme ii with inhibitor
|
K 3.1, 2.1
|
|
4k0tA
|
Structure of hcaix mimic (hcaii with 5 mutations in active site) in complex with chlorzolamide
|
K 3.1, 2.1
|
|
4qsbA
|
Crystal structure of human carbonic anhydrase isozyme ii with 3-{[(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio]acetyl}benzenesulfonamide
|
K 3.1, 2.1
|
|
4k0sA
|
Structure of hcaix mimic (hcaii with 5 mutations in active site) in complex with acetazolamide
|
K 3.1, 2.1
|
|
3mnaA
|
The crystal structure of human carbonic anhydrase ii in complex with a 1,3,5-triazine-substituted benzenesulfonamide inhibitor
|
K 3.1, 2.1
|
|
4n0xB
|
Room temperature crystal structure of human carbonic anhydrase ii in complex with thiophene-2-sulfonamide
|
K 3.1, 2.1
|
|
3mzcA
|
Human carbonic ahydrase ii in complex with a benzenesulfonamide inhibitor
|
K 3.1, 2.1
|
|
5msaA
|
Crystal structure of human carbonic anhydrase isozyme xii with 2,3,5,6-tetrafluoro-4-(propylthio)benzenesulfonamide
|
K 3.1, 2.1
|
2
|
5neeA
|
Crystal structure of human carbonic anhydrase ii in complex with the inhibitor 5-[2-(morpholine-4-carbonyl)1,3-oxazol-5-yl)]thiophene-2-sulfonammide
|
K 3.1, 2.1
|
|
2hfwA
|
Structural and kinetic analysis of proton shuttle residues in the active site of human carbonic anhydrase iii
|
K 3.1, 2.1
|
|
2f14A
|
Tne crystal structure of the human carbonic anhydrase ii in complex with a fluorescent inhibitor
|
K 3.1, 2.1
|
|
3d92A
|
Human carbonic anhydrase ii bound with substrate carbon dioxide
|
K 3.1, 2.1
|
|
4m2rA
|
Human carbonic anhydrase ii in complex with brinzolamide
|
K 3.1, 2.1
|
|
5ljqA
|
Crystal structure of human carbonic anhydrase ii in complex with the 4-(4-(phenoxymethyl)-1h-1,2,3-triazol-1-yl)benzenesulfonamide inhibitor
|
K 3.1, 2.1
|
|
3konA
|
Crystal structure of cobalt (ii) human carbonic anhydrase ii at ph 11.0
|
K 3.1, 2.1
|
|
4qk2A
|
Structural and catalytic effects of proline substitution and surface loop deletion in the extended active site of human carbonic anhydrase ii - e234p
|
K 3.1, 2.1
|
|
4z0qA
|
Carbonic anhydrase inhibitors: design and synthesis of new heteroaryl-n-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms (hca vii, hca ix, and hca xiv)
|
K 3.1, 2.1
|
|
6fe2A
|
Three dimensional structure of human carbonic anhydrase ix
|
K 3.1, 2.1
|
|
4gl1X
|
Structure of h64a/n62l/n67l human carbonic anhydrase ii triple mutant
|
K 3.1, 2.1
|
|
2nwoA
|
Structural and kinetic effect of hydrophobic mutations in the active site of human carbonic anhydrase ii
|
K 3.1, 2.1
|
|
1th9A
|
Effect of shuttle location and ph environment on h+ transfer in human carbonic anhydrase ii
|
K 3.1, 2.1
|
|
1caoA
|
Crystallographic studies of the binding of protonated and unprotonated inhibitors to carbonic anhydrase using hydrogen sulphide and nitrate anions
|
K 3.1, 2.1
|
|
4bf1A
|
Three dimensional structure of human carbonic anhydrase ii in complex with 5-(1-naphthalen-1-yl-1,2,3-triazol-4-yl)thiophene-2-sulfonamide
|
K 3.1, 2.1
|
|
3dc3A
|
Use of carbonic anhydrase ii, ix active-site mimic, for the purpose of screening inhibitors for possible anti-cancer properties
|
K 3.1, 2.1
|
2
|
2nnoA
|
Structure of inhibitor binding to carbonic anhydrase ii
|
K 3.1, 2.1
|
|
4qj0A
|
Crystal structure of catalytic domain of human carbonic anhydrase isozyme xii with inhibitor
|
K 3.1, 2.1
|
|
4cnvA
|
Surface residue engineering of bovine carbonic anhydrase to an extreme halophilic enzyme for potential application in postcombustion co2 capture
|
K 3.1, 2.1
|
|
4r59A
|
A carbonic anhydrase ix mimic in complex with a carbohydrate-based sulfamate
|
K 3.1, 2.1
|
|
4mltA
|
Structure of a monodentate 3-hydroxy-4h-pyran-4-thione ligand bound to hcaii
|
K 3.1, 2.1
|
|
3mnuA
|
Carbonic anhydrase inhibitors: crystallographic and solution binding studies for the interaction of a boron containing aromatic sulfamide with mammalian isoforms i-xv
|
K 3.1, 2.1
|
|
3s75B
|
The origin of the hydrophobic effect in the molecular recognition of arylsulfonamides by carbonic anhydrase
|
K 3.1, 2.1
|
|
4mdgA
|
Closo carborane carbonic anhydrase inhibitor
|
K 3.1, 2.1
|
|
5eijA
|
Carbonic anhydrase ii in complex with sulfonamide inhibitor
|
K 3.1, 2.1
|
|
3v2jA
|
Effect of sucrose and glycerol as cryoprotectans, on the inhibition of human carbonic anhydrase ii
|
K 3.1, 2.1
|
|
3ml5A
|
Crystal structure of the c183s/c217s mutant of human ca vii in complex with acetazolamide
|
K 3.1, 2.1
|
|
1cniA
|
X-ray crystallographic studies of engineered hydrogen bond networks in a protein-zinc binding site
|
K 3.1, 2.1
|
|
2hocA
|
Crystal structure of the human carbonic anhydrase ii in complex with the 5-(4-amino-3-chloro-5-fluorophenylsulfonamido)-1,3,4-thiadiazole-2-sulfonamide inhibitor
|
K 3.1, 2.1
|
|
4yxiA
|
Human carbonic anhydrase ii complexed with an inhibitor with a benzenesulfonamide group (2).
|
K 3.1, 2.1
|
|
5fnlA
|
Native state mass spectrometry, surface plasmon resonance and x-ray crystallography correlate strongly as a fragment screening combination
|
K 3.1, 2.1
|
|
4xz5A
|
Structure of the thermostable alpha-carbonic anydrase from thiomicrospira crunogena xcl-2 gammaproteobacterium
|
K 3.1, 2.1
|
|
4q7pA
|
Crystal structure of 1-hydroxy-3-methylpyridine-2(1h)-thione bound to hcaii
|
K 3.1, 2.1
|
|
5flrA
|
Native state mass spectrometry, surface plasmon resonance and x-ray crystallography correlate strongly as a fragment screening combination
|
K 3.1, 2.1
|
|
5flpA
|
Native state mass spectrometry, surface plasmon resonance and x-ray crystallography correlate strongly as a fragment screening combination
|
K 3.1, 2.1
|
|
4k0zA
|
Structure of hcaix mimic (hcaii with 5 mutations in active site) in complex with methazolamide
|
K 3.1, 2.1
|
|
4e3fA
|
Nucleophile recognition as an alternative inhibition mode for benzoic acid based carbonic anhydrase inhibitors
|
K 3.1, 2.1
|
|
4jszA
|
Benzenesulfonamide bound to hcaii h94c
|
K 3.1, 2.1
|
|
2eu2A
|
Human carbonic anhydrase ii in complex with novel inhibitors
|
K 3.1, 2.1
|
2
|
5tuoA
|
Crystal structure of the complex of helicobacter pylori alpha-carbonic anhydrase with 5-amino-1,3,4-thiadiazole-2-sulfonamide inhibitor.
|
K 3.1, 2.1
|
|
4n16A
|
Structure of cholate bound to human carbonic anhydrase ii
|
K 3.1, 2.1
|
|
5e2kA
|
Crystal structure of human carbonic anhydrase ii in complex with the 4-(3-aminophenyl)benzenesulfonamide inhibitor
|
K 3.1, 2.1
|
2
|
2nnsA
|
Structure of inhibitor binding to carbonic anhydrase ii
|
K 3.1, 2.1
|
|
5jehB
|
Human carbonic anhydrase ii (l198a) complexed with benzo[d]thiazole-2-sulfonamide
|
K 3.1, 2.1
|
|
3m1qA
|
Carbonic anhydrase ii mutant w5c-h64c with opened disulfide bond
|
K 3.1, 2.1
|
|
3myqA
|
Crystal structure of human carbonic anhydrase isozyme ii with 2-chloro-5-[(1h-imidazo[4,5-c]quinolin-2-ylsulfanyl)acetyl]benzenesulfonamide
|
K 3.1, 2.1
|
|
1zsbA
|
Carbonic anhydrase ii mutant e117q, transition state analogue acetazolamide
|
K 3.1, 2.1
|
|
1oknA
|
Carbonic anhydrase ii complex with the 1okn inhibitor 4-sulfonamide-[1-(4-n-(5-fluorescein thiourea)butane)]
|
K 3.1, 2.1
|
|
6d1lA
|
Design, synthesis, and x-ray of selenides bearing benzenesulfonamide moiety with neuropathic pain modulating effects
|
K 3.1, 2.1
|
|
5jmzA
|
Carbonic anhydrase ix-mimic in complex with u-no2
|
K 3.1, 2.1
|
|
4hu1A
|
Crystal structure of human carbonic anhydrase isozyme xiii with the inhibitor.
|
K 3.1, 2.1
|
|
1cahA
|
Structure of cobalt carbonic anhydrase complexed with bicarbonate
|
K 3.1, 2.1
|
|
5wlrA
|
Carbonic anhydrase ix-mimic in complex with aryloxy-2-hydroxypropylammine sulfonamide
|
K 3.1, 2.1
|
|
1fr4A
|
X-ray crystal structure of copper-bound f93i/f95m/w97v carbonic anhydrase (caii) variant
|
K 3.1, 2.1
|
|
4q90A
|
Crystal structure of 4-methylpyridine-2(1h)-thione bound to human carbonic anhydrase ii
|
K 3.1, 2.1
|
|
5amgA
|
Three dimensional structure of human carbonic anhydrase ii in complex with 2-(pentylsulfamoyl)-4-sulfamoylbenzoic acid
|
K 3.1, 2.1
|
|
4fvnA
|
Carbonic anhydrase ii in complex with n-(tetrahydropyrimidin-2(1h)-ylidene)sulfuric diamide
|
K 3.1, 2.1
|
|
3vbdA
|
Complex of human carbonic anhydrase ii with 4-(6-methoxy-3,4-dihydroisoquinolin-1-yl)benzenesulfonamide
|
K 3.1, 2.1
|
|
4q7wA
|
Crystal structure of 1-hydroxy-6-methylpyridine-2(1h)-thione bound to human carbonic anhydrase ii
|
K 3.1, 2.1
|
|
3k7kA
|
Crystal structure of the complex between carbonic anhydrase ii and anions
|
K 3.1, 2.1
|
|
3v3iB
|
Kinetic and structural studies of thermostabilized mutants of hca ii.
|
K 3.1, 2.1
|
|
3r16A
|
Human caii bound to n-(4-sulfamoylphenyl)-2-(thiophen-2-yl) acetamide
|
K 3.1, 2.1
|
|
6g4tA
|
The crystal structure of uninhibited c183s/c217s mutant of human ca vii
|
K 3.1, 2.1
|
|
1xq0A
|
Structure of human carbonic anhydrase ii with 4-[(3-bromo-4-o-sulfamoylbenzyl)(4-cyanophenyl)amino]-4h-[1,2,4]-triazole
|
K 3.1, 2.1
|
|
5a25A
|
Rational engineering of a mesophilic carbonic anhydrase to an extreme halotolerant biocatalyst
|
K 3.1, 2.1
|
|
4jsaA
|
Benzenesulfonamide complexed with hcaii h94d
|
K 3.1, 2.1
|
|
2fnmA
|
Activation of human carbonic anhdyrase ii by exogenous proton donors
|
K 3.1, 2.1
|
|
4rh2A
|
Crystal structure of human carbonic anhydrase ii in complex with 2-(6-hydroxy-3-oxo-3h-xanthen-9-yl)-5-{3-1-(4-sulfamoyl-phenyl)-1h-[1,2,3]triazol-4-ylmethyl-thioureido}-benzoic acid
|
K 3.1, 2.1
|
|
1razA
|
The structure of human carbonic anhydrase ii in complex with bromide and azide
|
K 3.1, 2.1
|
|
4q78A
|
Structure-assisted design of carborane-based inhibitors of carbonic anhydrase
|
K 3.1, 2.1
|
|
4yxuA
|
Human carbonic anhydrase ii complexed with an inhibitor with a benzenesulfonamide group (4).
|
K 3.1, 2.1
|
|
1cazA
|
Wild-type and e106q mutant carbonic anhydrase complexed with acetate
|
K 3.1, 2.1
|
|
3qykA
|
Human carbonic anhydrase ii complexed with triple ring benzene sulfonamide inhibitor
|
K 3.1, 2.1
|
|
3ryxB
|
Fluoroalkyl and alkyl chains have similar hydrophobicities in binding to the hydrophobic wall of carbonic anhydrase
|
K 3.1, 2.1
|
|
4q8yA
|
Crystal structure of 2-hydroxyisoquinoline-1(2h)-thione bound to human carbonic anhydrase ii
|
K 3.1, 2.1
|
|
5e2rA
|
The crystal structure of the human carbonic anhydrase ii in complex with a 1,1'-biphenyl-4-sulfonamide inhibitor
|
K 3.1, 2.1
|
|
1t9nA
|
Effect of shuttle location and ph environment on h+ transfer in human carbonic anhydrase ii
|
K 3.1, 2.1
|
|
6fe1A
|
Three dimensional structure of human carbonic anhydrase ix in complex with benzenesulfonamide.
|
K 3.1, 2.1
|
|
5ca2A
|
Conformational mobility of his-64 in the thr-200 (right arrow) ser mutant of human carbonic anhydrase ii
|
K 3.1, 2.1
|
|
5flqA
|
Native state mass spectrometry, surface plasmon resonance and x-ray crystallography correlate strongly as a fragment screening combination
|
K 3.1, 2.1
|
|
2fmzA
|
Carbonic anhydrase activators. activation of isoforms i, ii, iv, va, vii and xiv with l- and d- phenylalanine, structure with d-phenylalanine.
|
K 3.1, 2.1
|
|
4pyxA
|
Crystal structure of human carbonic anhydrase isozyme ii with inhibitor
|
K 3.1, 2.1
|
|
2hncA
|
Crystal structure of the human carbonic anhydrase ii in complex with the 5-amino-1,3,4-thiadiazole-2-sulfonamide inhibitor.
|
K 3.1, 2.1
|
|
5jq0A
|
Crystal structure of human carbonic anhydrase ii in complex with benzoxaborole at ph=8.7
|
K 3.1, 2.1
|
|
5n1rA
|
Crystal structure of human carbonic anhydrase ii in complex with the inhibitor 4'-pyrazol-1-ylmethyl-biphenyl-4-sulfonamide
|
K 3.1, 2.1
|
|
5bnlA
|
Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins
|
K 3.1, 2.1
|
|
3hkuA
|
Human carbonic anhydrase ii in complex with topiramate
|
K 3.1, 2.1
|
|
4kuyA
|
Crystal structure of human carbonic anhydrase ii in complex with the 5-(3-(o-tolylsulfonyl)ureido)pyridine-2-sulfonamide inhibitor
|
K 3.1, 2.1
|
|
4ilxA
|
Structure of human carbonic anhydrase ii in complex with an adamantyl sulfonamide inhibitor
|
K 3.1, 2.1
|
|
4zx1A
|
Engineered carbonic anhydrase ix mimic in complex with a glucosyl sulfamate inhibitor
|
K 3.1, 2.1
|
|
3dvdA
|
X-ray crystal structure of mutant n62d of human carbonic anhydrase ii
|