1IPAA

Crystal structure of rna 2'-o ribose methyltransferase
Knot K +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 192-232 41 1-191, 233-263 191 31 knot
Chain Sequence
MRITSTANPRIKELARLLERKHRDSQRRFLIEGAREIERALQAGIELEQALVWEGGLNPEEQQVYAAL-----LALLEVSEAVLKKLSVRDNPAGLIALARMPERTLEEYRPSPDALILVAVGLEKPGNLGAVLRSADAAGAEAVLVAGGVDLYSPQVIRNSTGVVFSLRTLAASESEVLDWIKQHNLPLVATTPHAEALYWEANLRPPVAIAVGPEHEGLRAAWLEAAQTQVRIPMQGQADSLNVSVSAALLLYEALRQRLL
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
3.1 187-228 42 1-186, 229-258 186 30 knot
view details
2.1 185-225 41 1-184 231-258 226-230 184 28 slipknot
view details
2.1 189-232 44 1-186, 248-258 187-188, 233-247 186 11 slipknot
view details
3.1 189-247 59 1-186, 250-258 187-188, 248-249 186 9 slipknot
sequence length 263
structure length 258
publication title An enzyme with a deep trefoil knot for the active-site architecture.
pubmed doi rcsb
molecule tags Transferase
molecule keywords RNA 2'-O-RIBOSE METHYLTRANSFERASE
source organism Thermus thermophilus
missing residues 69-73
total genus Genus: 81
ec nomenclature ec 2.1.1.-:
pdb deposition date 2001-05-02
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00588 SpoU_methylase SpoU rRNA Methylase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1330.30 Alpha Beta 2-Layer Sandwich 60s Ribosomal Protein L30; Chain: A; 60s Ribosomal Protein L30; Chain: A; 1ipaA01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 1ipaA02
2CX8A 3QUVA 2O3AA 3AXZA 3IC6A 1O6DA 2I6DA 1V2XA 1VH0A 3NK6A 3AIAA 1UAMA 3E5YA 1UALA 1IPAA 1X7OA 3ILKA 1V6ZA 4H3ZA 1VHKA 1UAJA 1VHYA 4CNFB 1P9PA 3GYQA 2Z0YA 3AI9X 3IEFA 4CNGB 1K3RA 3DCMX 3KTYA 4CNEB 1X7PA 2YY8A 1ZJRA 2QMMA 3L8UA 1NS5A 4IG6A 1MXIA 1GZ0A 3ONPA 3KNUA 3N4KA 3NK7A 4E8BA 1NXZA 3KY7A 2QWVA 1TO0A 4H3YA 2HA8A 4FAKA 1UAKA 1J85A 3N4JA
chains in the KnotProt database with same CATH superfamily
2CX8A 3QUVA 2O3AA 3AXZA 3IC6A 1O6DA 2I6DA 1V2XA 1VH0A 3NK6A 3AIAA 1UAMA 3E5YA 1UALA 1IPAA 1X7OA 3ILKA 1V6ZA 4H3ZA 1VHKA 1UAJA 1VHYA 4CNFB 1P9PA 3GYQA 2Z0YA 3AI9X 3IEFA 4CNGB 1K3RA 3DCMX 3KTYA 4CNEB 1X7PA 2YY8A 1ZJRA 2QMMA 3L8UA 1NS5A 4IG6A 1MXIA 1GZ0A 3ONPA 3KNUA 3N4KA 3NK7A 4E8BA 1NXZA 3KY7A 2QWVA 1TO0A 4H3YA 2HA8A 4FAKA 1UAKA 1J85A 3N4JA
chains in the KnotProt database with same CATH topology
2CX8A 3QUVA 2O3AA 3AXZA 3IC6A 1O6DA 2I6DA 1V2XA 1VH0A 3NK6A 3AIAA 1UAMA 3E5YA 1UALA 1IPAA 1X7OA 3ILKA 1V6ZA 4H3ZA 1VHKA 1UAJA 1VHYA 4CNFB 1P9PA 3GYQA 2Z0YA 3AI9X 3IEFA 4CNGB 1K3RA 3DCMX 3KTYA 4CNEB 1X7PA 2YY8A 1ZJRA 2QMMA 3L8UA 1NS5A 4IG6A 1MXIA 1GZ0A 3ONPA 3KNUA 3N4KA 3NK7A 4E8BA 1NXZA 3KY7A 2QWVA 1TO0A 4H3YA 2HA8A 4FAKA 1UAKA 1J85A 3N4JA
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 2CX8 A;  3QUV A;  2O3A A;  3AXZ A;  3IC6 A;  1O6D A;  2I6D A;  1V2X A;  1VH0 A;  3NK6 A;  3AIA A;  1UAM A;  3E5Y A;  1UAL A;  1IPA A;  1X7O A;  3ILK A;  1V6Z A;  4H3Z A;  1VHK A;  1UAJ A;  1VHY A;  4CNF B;  1P9P A;  3GYQ A;  2Z0Y A;  3AI9 X;  3IEF A;  4CNG B;  1K3R A;  3DCM X;  3KTY A;  4CNE B;  1X7P A;  2YY8 A;  1ZJR A;  2QMM A;  3L8U A;  1NS5 A;  4IG6 A;  1MXI A;  1GZ0 A;  3ONP A;  3KNU A;  3N4K A;  3NK7 A;  4E8B A;  1NXZ A;  3KY7 A;  2QWV A;  1TO0 A;  4H3Y A;  2HA8 A;  4FAK A;  1UAK A;  1J85 A;  3N4J A; 
#chains in the KnotProt database with same CATH topology
 2CX8 A;  3QUV A;  2O3A A;  3AXZ A;  3IC6 A;  1O6D A;  2I6D A;  1V2X A;  1VH0 A;  3NK6 A;  3AIA A;  1UAM A;  3E5Y A;  1UAL A;  1IPA A;  1X7O A;  3ILK A;  1V6Z A;  4H3Z A;  1VHK A;  1UAJ A;  1VHY A;  4CNF B;  1P9P A;  3GYQ A;  2Z0Y A;  3AI9 X;  3IEF A;  4CNG B;  1K3R A;  3DCM X;  3KTY A;  4CNE B;  1X7P A;  2YY8 A;  1ZJR A;  2QMM A;  3L8U A;  1NS5 A;  4IG6 A;  1MXI A;  1GZ0 A;  3ONP A;  3KNU A;  3N4K A;  3NK7 A;  4E8B A;  1NXZ A;  3KY7 A;  2QWV A;  1TO0 A;  4H3Y A;  2HA8 A;  4FAK A;  1UAK A;  1J85 A;  3N4J A; 
#chains in the KnotProt database with same CATH homology
 2CX8 A;  3QUV A;  2O3A A;  3AXZ A;  3IC6 A;  1O6D A;  2I6D A;  1V2X A;  1VH0 A;  3NK6 A;  3AIA A;  1UAM A;  3E5Y A;  1UAL A;  1IPA A;  1X7O A;  3ILK A;  1V6Z A;  4H3Z A;  1VHK A;  1UAJ A;  1VHY A;  4CNF B;  1P9P A;  3GYQ A;  2Z0Y A;  3AI9 X;  3IEF A;  4CNG B;  1K3R A;  3DCM X;  3KTY A;  4CNE B;  1X7P A;  2YY8 A;  1ZJR A;  2QMM A;  3L8U A;  1NS5 A;  4IG6 A;  1MXI A;  1GZ0 A;  3ONP A;  3KNU A;  3N4K A;  3NK7 A;  4E8B A;  1NXZ A;  3KY7 A;  2QWV A;  1TO0 A;  4H3Y A;  2HA8 A;  4FAK A;  1UAK A;  1J85 A;  3N4J A; 
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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