5YS5A

Crystal structure of multicopper oxidase cueo g304k mutant with seven copper ions
Note, that the numbers in the matrix denote the consecutive residues in the loop, not the index of amino acids in the chain!
Knot K 2x -31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
- 31 73-118 46 1-72, 119-137 72 19 knot
Fingerprint Knot forming loop Loop type
K -31 Arg31 ... His103 <->
Bridging ionCu702
<-> His501 ... His494 <->
Bridging ionCu706
<-> Glu110 ... His143 <->
Bridging ionCu703
<-> His448 ... His443 <->
Bridging ionCu701
<-> His505 ...
Chain closureVal516 <-> Arg31
probabilistic
K -31
Chain closureArg31 <-> Val516
... His505 <->
Bridging ionCu701
<-> His443 ... His448 <->
Bridging ionCu703
<-> His143 ... Asp132 <->
Bridging ionCu704
<-> His488 ... His501 <->
Bridging ionCu702
<-> His103 ... Arg31
probabilistic
Chain Sequence
RPTLPIPDLLTTDARNRIQLTIGAGQSTFGGKTATTWGYNGNLLGPAVKLQRGKAVTVDIYNQLTEETTLHWHGLEVPGEVDGGPQGIIPPGGKRSVTLNVDQPAATCWFHPHQHGKTGRQVAMGLAGLVVIEDDEILKLMLPKQWGIDDVPVIVQDKKFSADGQIDYQLDVMTAAVGWFGDTLLTNGAIYPQHAAPRGWLRLRLLNGCNARSLNFATSDNRPLYVIASDGGLLPEPVKVSELPVLMGERFEVLVEVNDNKPFDLVTLPVSQMKMAIAPFDKPHPVMRIQPIAISASGALPDTLSSLPALPSLEGLTVRKLQLSMDPMLDMMGMQMLME-----------------------------GGKFDFHHANKINGQAFDMNKPMFAAAKGQYERWVISGVGDMMLHPFHIHGTQFRILSENGKPPAAHRAGWKDTVKVEGNVSEVLVKFNHDAPKEHAYMAHCHLLEHEDTGMMLGFTV
sequence length 486
structure length 457
publication title Crystal structures of multicopper oxidase CueO G304K mutant: structural basis of the increased laccase activity
pubmed doi rcsb
molecule tags Metal binding protein
molecule keywords Blue copper oxidase CueO
source organism Escherichia coli k12
missing residues 340-368
total genus Genus: 124
ec nomenclature
pdb deposition date 2017-11-13
KnotProt deposition date 2018-10-19
Image from the rcsb pdb (www.rcsb.org)
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