1AOCA

Japanese horseshoe crab coagulogen
Note, that the numbers in the matrix denote the consecutive residues in the loop, not the index of amino acids in the chain!
Knot K 2x -31 1x +31

  Help Knotting data interpretation Full screen
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
+ 31 10-57 48 1-9, 58-59 9 2 knot
Fingerprint Knot forming loop Loop type
K +31 Cys8 <-> Cys167 ... Cys172 <-> Cys134 ... Cys121 <-> Cys65 ... Cys60 <-> Cys161 ... Cys140 <-> Cys88 ... Cys95 <-> Cys10 ... Cys8 covalent
K -31
Chain closureAla1 <-> Phe175
... Cys170 <-> Cys127 ... Cys95 <-> Cys10 ... Cys60 <-> Cys161 ... Cys140 <-> Cys88 ... Cys75 <-> Cys168 ... Cys167 <-> Cys8 ... Ala1		 probabilistic
K -31
Chain closureAla1 <-> Phe175
... Cys170 <-> Cys127 ... Cys121 <-> Cys65 ... Cys60 <-> Cys161 ... Cys140 <-> Cys88 ... Cys75 <-> Cys168 ... Cys167 <-> Cys8 ... Ala1		 probabilistic
Chain Sequence
ADTNAPICLCDEPGVLGRTQIVTTEIKDKIEKAVEAVAQESGVSGRGFSIFSHHPVFRECGKYECRTVRPEHSRCYNFPPFTHFKSECPVSTRDCEPVFGYTVAGEFRVIVQAPRAGFRQCVWQHKCRFGSNSCGYNGRCTQQRSVVRLVTYNLEKDGFLCESFRTCCGCPCRSF
Cysteine knot

  Help Cysteine knot data interpretation Full screen
Loop Piercing
view details
127-c-134-b-172-c-170 88-b-140
Chain Sequence
ADTNAPICLCDEPGVLGRTQIVTTEIKDKIEKAVEAVAQESGVSGRGFSIFSHHPVFRECGKYECRTVRPEHSRCYNFPPFTHFKSECPVSTRDCEPVFGYTVAGEFRVIVQAPRAGFRQCVWQHKCRFGSNSCGYNGRCTQQRSVVRLVTYNLEKDGFLCESFRTCCGCPCRSF
sequence length 175
structure length 175
publication title Crystal structure of a coagulogen, the clotting protein from horseshoe crab: a structural homologue of nerve growth factor.
pubmed rcsb
molecule tags Coagulation factor
molecule keywords COAGULOGEN
total genus Genus: 40
ec nomenclature
pdb deposition date 1996-11-28
KnotProt deposition date 2018-10-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02035 Coagulin Coagulin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.90.10 Mainly Beta Ribbon Cystine Knot Cytokines, subunit B Cystine-knot cytokines 1aocA00
2.10.90.10 Mainly Beta Ribbon Cystine Knot Cytokines, subunit B Cystine-knot cytokines 1aocA00
1LXIA 1QTYV 3QTKB 2VPFH 2TGIA 1HRPB 1FLTW 1KLAA 1MJVA 1VPPW 3KFDB 2C7WB 1ES7A 1PDGC 3MJGB 3KFDD 2V5EB 3EO1I 1TZHV 2P6AA 2VPFE 1BMPA 2X1WD 3EO1L 2QJ9B 2VPFB 3B4VB 1QTYW 1SGFY 1ZKZA 2XACB 1VPFC 1HCNB 3HH2A 3QTKF 1ES7C 1REWB 3FUBB 1VPFD 1XWDD 2ARPA 2QR0D 2R53B 1E9JA 3BDYV 1NYUB 1LX5A 1SGFB 1WQ9A 1FZVA 2GNND 2X1WA 1AOCB 2GYRB 1WAQA 2QR0O 3QTKE 2PJYA 3QTKD 1VPFA 1XWDA 2B0UA 2VPFF 3KFDC 3BK3B 1QFWB 2ARVA 2H62A 1BNDB 2QCQA 1CZ8V 2R52A 2ASKA 2X1WC 2GNNA 1REUA 2FJHV 1BJ1V 1KATW 3B4VE 2VWEB 2BHKA 2P6AB 1AGQB 1FL7B 2FJGV 2QJAB 2QR0C 2QR0I 3QTKA 1HRPA 3EVSB 2GOOD 2VPFD 3KFDA 2C7WA 2QR0J 2QCWB 1B8MA 2GNNC 2GYRE 3FUBD 1KLCB 2GYZA 1CZ8W 1PDGB 3MJGA 2QJBB 1TZHW 2GH0D 1NYUD 1BJ1W 3QTKC 1NYSB 2GOOA 2GYRD 2QJ9A 1FLTV 1KLAB 1MJVB 1RV6V 1BTGB 2VPFA 3B4VF 1QTYS 1VPPV 1TZIV 1HCNA 2XACA 1REWA 1TGKA 1KTZA 1S4YB 2R53A 3BMPA 1AOCA 2GYRF 2VPFC 1FL7C 1AGQD 1FL7D 3HH2B 1RV6W 3BK3A 1QFWA 2X1XE 2GH0C 1BNDA 1DZ7A 1WQ8A 1B98A 1WQ9B 2FJHW 1FZVB 2GYRC 2XV7A 2X1WB 2VWEA 1TGJA 3EO1C 1HD4A 2VPFG 3B4VA 1AGQA 1FL7A 1QTYR 1XWDE 2FJGW 2QJAA 2QR0P 2H64A 1VPFB 1XWDB 2B0UB 2ARVB 2H62B 2QCQB 2QCWA 1TFGA 2R52B 2QR0V 1M4UL 2ASKB 1S4YD 2GNNB 2QR0U 1KLCA 1PDGA 1KATV 2QJBA 2GYRA 1AGQC 1NT3A
chains in the KnotProt database with same CATH superfamily
1LXIA 1QTYV 3QTKB 2VPFH 2TGIA 1HRPB 1FLTW 1KLAA 1MJVA 1VPPW 3KFDB 2C7WB 1ES7A 1PDGC 3MJGB 3KFDD 2V5EB 3EO1I 1TZHV 2P6AA 2VPFE 1BMPA 2X1WD 3EO1L 2QJ9B 2VPFB 3B4VB 1QTYW 1SGFY 1ZKZA 2XACB 1VPFC 1HCNB 3HH2A 3QTKF 1ES7C 1REWB 3FUBB 1VPFD 1XWDD 2ARPA 2QR0D 2R53B 1E9JA 3BDYV 1NYUB 1LX5A 1SGFB 1WQ9A 1FZVA 2GNND 2X1WA 1AOCB 2GYRB 1WAQA 2QR0O 3QTKE 2PJYA 3QTKD 1VPFA 1XWDA 2B0UA 2VPFF 3KFDC 3BK3B 1QFWB 2ARVA 2H62A 1BNDB 2QCQA 1CZ8V 2R52A 2ASKA 2X1WC 2GNNA 1REUA 2FJHV 1BJ1V 1KATW 3B4VE 2VWEB 2BHKA 2P6AB 1AGQB 1FL7B 2FJGV 2QJAB 2QR0C 2QR0I 3QTKA 1HRPA 3EVSB 2GOOD 2VPFD 3KFDA 2C7WA 2QR0J 2QCWB 1B8MA 2GNNC 2GYRE 3FUBD 1KLCB 2GYZA 1CZ8W 1PDGB 3MJGA 2QJBB 1TZHW 2GH0D 1NYUD 1BJ1W 3QTKC 1NYSB 2GOOA 2GYRD 2QJ9A 1FLTV 1KLAB 1MJVB 1RV6V 1BTGB 2VPFA 3B4VF 1QTYS 1VPPV 1TZIV 1HCNA 2XACA 1REWA 1TGKA 1KTZA 1S4YB 2R53A 3BMPA 1AOCA 2GYRF 2VPFC 1FL7C 1AGQD 1FL7D 3HH2B 1RV6W 3BK3A 1QFWA 2X1XE 2GH0C 1BNDA 1DZ7A 1WQ8A 1B98A 1WQ9B 2FJHW 1FZVB 2GYRC 2XV7A 2X1WB 2VWEA 1TGJA 3EO1C 1HD4A 2VPFG 3B4VA 1AGQA 1FL7A 1QTYR 1XWDE 2FJGW 2QJAA 2QR0P 2H64A 1VPFB 1XWDB 2B0UB 2ARVB 2H62B 2QCQB 2QCWA 1TFGA 2R52B 2QR0V 1M4UL 2ASKB 1S4YD 2GNNB 2QR0U 1KLCA 1PDGA 1KATV 2QJBA 2GYRA 1AGQC 1NT3A
chains in the KnotProt database with same CATH topology
1LXIA 1QTYV 3QTKB 2VPFH 2TGIA 1HRPB 1FLTW 1KLAA 1MJVA 1VPPW 3KFDB 2C7WB 1ES7A 1PDGC 3MJGB 3KFDD 2V5EB 3EO1I 1TZHV 2P6AA 2VPFE 1BMPA 2X1WD 3EO1L 2QJ9B 2VPFB 3B4VB 1QTYW 1SGFY 1ZKZA 2XACB 1VPFC 1HCNB 3HH2A 3QTKF 1ES7C 1REWB 3FUBB 1VPFD 1XWDD 2ARPA 2QR0D 2R53B 1E9JA 3BDYV 1NYUB 1LX5A 1SGFB 1WQ9A 1FZVA 2GNND 2X1WA 1AOCB 2GYRB 1WAQA 2QR0O 3QTKE 2PJYA 3QTKD 1VPFA 1XWDA 2B0UA 2VPFF 3KFDC 3BK3B 1QFWB 2ARVA 2H62A 1BNDB 2QCQA 1CZ8V 2R52A 2ASKA 2X1WC 2GNNA 1REUA 2FJHV 1BJ1V 1KATW 3B4VE 2VWEB 2BHKA 2P6AB 1AGQB 1FL7B 2FJGV 2QJAB 2QR0C 2QR0I 3QTKA 1HRPA 3EVSB 2GOOD 2VPFD 3KFDA 2C7WA 2QR0J 2QCWB 1B8MA 2GNNC 2GYRE 3FUBD 1KLCB 2GYZA 1CZ8W 1PDGB 3MJGA 2QJBB 1TZHW 2GH0D 1NYUD 1BJ1W 3QTKC 1NYSB 2GOOA 2GYRD 2QJ9A 1FLTV 1KLAB 1MJVB 1RV6V 1BTGB 2VPFA 3B4VF 1QTYS 1VPPV 1TZIV 1HCNA 2XACA 1REWA 1TGKA 1KTZA 1S4YB 2R53A 3BMPA 1AOCA 2GYRF 2VPFC 1FL7C 1AGQD 1FL7D 3HH2B 1RV6W 3BK3A 1QFWA 2X1XE 2GH0C 1BNDA 1DZ7A 1WQ8A 1B98A 1WQ9B 2FJHW 1FZVB 2GYRC 2XV7A 2X1WB 2VWEA 1TGJA 3EO1C 1HD4A 2VPFG 3B4VA 1AGQA 1FL7A 1QTYR 1XWDE 2FJGW 2QJAA 2QR0P 2H64A 1VPFB 1XWDB 2B0UB 2ARVB 2H62B 2QCQB 2QCWA 1TFGA 2R52B 2QR0V 1M4UL 2ASKB 1S4YD 2GNNB 2QR0U 1KLCA 1PDGA 1KATV 2QJBA 2GYRA 1AGQC 1NT3A
chains in the KnotProt database with same CATH homology

  
#chains in the KnotProt database with same CATH superfamily
 1LXI A;  1QTY V;  3QTK B;  2VPF H;  2TGI A;  1HRP B;  1FLT W;  1KLA A;  1MJV A;  1VPP W;  3KFD B;  2C7W B;  1ES7 A;  1PDG C;  3MJG B;  3KFD D;  2V5E B;  3EO1 I;  1TZH V;  2P6A A;  2VPF E;  1BMP A;  2X1W D;  3EO1 L;  2QJ9 B;  2VPF B;  3B4V B;  1QTY W;  1SGF Y;  1ZKZ A;  2XAC B;  1VPF C;  1HCN B;  3HH2 A;  3QTK F;  1ES7 C;  1REW B;  3FUB B;  1VPF D;  1XWD D;  2ARP A;  2QR0 D;  2R53 B;  1E9J A;  3BDY V;  1NYU B;  1LX5 A;  1SGF B;  1WQ9 A;  1FZV A;  2GNN D;  2X1W A;  1AOC B;  2GYR B;  1WAQ A;  2QR0 O;  3QTK E;  2PJY A;  3QTK D;  1VPF A;  1XWD A;  2B0U A;  2VPF F;  3KFD C;  3BK3 B;  1QFW B;  2ARV A;  2H62 A;  1BND B;  2QCQ A;  1CZ8 V;  2R52 A;  2ASK A;  2X1W C;  2GNN A;  1REU A;  2FJH V;  1BJ1 V;  1KAT W;  3B4V E;  2VWE B;  2BHK A;  2P6A B;  1AGQ B;  1FL7 B;  2FJG V;  2QJA B;  2QR0 C;  2QR0 I;  3QTK A;  1HRP A;  3EVS B;  2GOO D;  2VPF D;  3KFD A;  2C7W A;  2QR0 J;  2QCW B;  1B8M A;  2GNN C;  2GYR E;  3FUB D;  1KLC B;  2GYZ A;  1CZ8 W;  1PDG B;  3MJG A;  2QJB B;  1TZH W;  2GH0 D;  1NYU D;  1BJ1 W;  3QTK C;  1NYS B;  2GOO A;  2GYR D;  2QJ9 A;  1FLT V;  1KLA B;  1MJV B;  1RV6 V;  1BTG B;  2VPF A;  3B4V F;  1QTY S;  1VPP V;  1TZI V;  1HCN A;  2XAC A;  1REW A;  1TGK A;  1KTZ A;  1S4Y B;  2R53 A;  3BMP A;  1AOC A;  2GYR F;  2VPF C;  1FL7 C;  1AGQ D;  1FL7 D;  3HH2 B;  1RV6 W;  3BK3 A;  1QFW A;  2X1X E;  2GH0 C;  1BND A;  1DZ7 A;  1WQ8 A;  1B98 A;  1WQ9 B;  2FJH W;  1FZV B;  2GYR C;  2XV7 A;  2X1W B;  2VWE A;  1TGJ A;  3EO1 C;  1HD4 A;  2VPF G;  3B4V A;  1AGQ A;  1FL7 A;  1QTY R;  1XWD E;  2FJG W;  2QJA A;  2QR0 P;  2H64 A;  1VPF B;  1XWD B;  2B0U B;  2ARV B;  2H62 B;  2QCQ B;  2QCW A;  1TFG A;  2R52 B;  2QR0 V;  1M4U L;  2ASK B;  1S4Y D;  2GNN B;  2QR0 U;  1KLC A;  1PDG A;  1KAT V;  2QJB A;  2GYR A;  1AGQ C;  1NT3 A; 
#chains in the KnotProt database with same CATH topology
 1LXI A;  1QTY V;  3QTK B;  2VPF H;  2TGI A;  1HRP B;  1FLT W;  1KLA A;  1MJV A;  1VPP W;  3KFD B;  2C7W B;  1ES7 A;  1PDG C;  3MJG B;  3KFD D;  2V5E B;  3EO1 I;  1TZH V;  2P6A A;  2VPF E;  1BMP A;  2X1W D;  3EO1 L;  2QJ9 B;  2VPF B;  3B4V B;  1QTY W;  1SGF Y;  1ZKZ A;  2XAC B;  1VPF C;  1HCN B;  3HH2 A;  3QTK F;  1ES7 C;  1REW B;  3FUB B;  1VPF D;  1XWD D;  2ARP A;  2QR0 D;  2R53 B;  1E9J A;  3BDY V;  1NYU B;  1LX5 A;  1SGF B;  1WQ9 A;  1FZV A;  2GNN D;  2X1W A;  1AOC B;  2GYR B;  1WAQ A;  2QR0 O;  3QTK E;  2PJY A;  3QTK D;  1VPF A;  1XWD A;  2B0U A;  2VPF F;  3KFD C;  3BK3 B;  1QFW B;  2ARV A;  2H62 A;  1BND B;  2QCQ A;  1CZ8 V;  2R52 A;  2ASK A;  2X1W C;  2GNN A;  1REU A;  2FJH V;  1BJ1 V;  1KAT W;  3B4V E;  2VWE B;  2BHK A;  2P6A B;  1AGQ B;  1FL7 B;  2FJG V;  2QJA B;  2QR0 C;  2QR0 I;  3QTK A;  1HRP A;  3EVS B;  2GOO D;  2VPF D;  3KFD A;  2C7W A;  2QR0 J;  2QCW B;  1B8M A;  2GNN C;  2GYR E;  3FUB D;  1KLC B;  2GYZ A;  1CZ8 W;  1PDG B;  3MJG A;  2QJB B;  1TZH W;  2GH0 D;  1NYU D;  1BJ1 W;  3QTK C;  1NYS B;  2GOO A;  2GYR D;  2QJ9 A;  1FLT V;  1KLA B;  1MJV B;  1RV6 V;  1BTG B;  2VPF A;  3B4V F;  1QTY S;  1VPP V;  1TZI V;  1HCN A;  2XAC A;  1REW A;  1TGK A;  1KTZ A;  1S4Y B;  2R53 A;  3BMP A;  1AOC A;  2GYR F;  2VPF C;  1FL7 C;  1AGQ D;  1FL7 D;  3HH2 B;  1RV6 W;  3BK3 A;  1QFW A;  2X1X E;  2GH0 C;  1BND A;  1DZ7 A;  1WQ8 A;  1B98 A;  1WQ9 B;  2FJH W;  1FZV B;  2GYR C;  2XV7 A;  2X1W B;  2VWE A;  1TGJ A;  3EO1 C;  1HD4 A;  2VPF G;  3B4V A;  1AGQ A;  1FL7 A;  1QTY R;  1XWD E;  2FJG W;  2QJA A;  2QR0 P;  2H64 A;  1VPF B;  1XWD B;  2B0U B;  2ARV B;  2H62 B;  2QCQ B;  2QCW A;  1TFG A;  2R52 B;  2QR0 V;  1M4U L;  2ASK B;  1S4Y D;  2GNN B;  2QR0 U;  1KLC A;  1PDG A;  1KAT V;  2QJB A;  2GYR A;  1AGQ C;  1NT3 A; 
#chains in the KnotProt database with same CATH homology
 1LXI A;  1QTY V;  3QTK B;  2VPF H;  2TGI A;  1HRP B;  1FLT W;  1KLA A;  1MJV A;  1VPP W;  3KFD B;  2C7W B;  1ES7 A;  1PDG C;  3MJG B;  3KFD D;  2V5E B;  3EO1 I;  1TZH V;  2P6A A;  2VPF E;  1BMP A;  2X1W D;  3EO1 L;  2QJ9 B;  2VPF B;  3B4V B;  1QTY W;  1SGF Y;  1ZKZ A;  2XAC B;  1VPF C;  1HCN B;  3HH2 A;  3QTK F;  1ES7 C;  1REW B;  3FUB B;  1VPF D;  1XWD D;  2ARP A;  2QR0 D;  2R53 B;  1E9J A;  3BDY V;  1NYU B;  1LX5 A;  1SGF B;  1WQ9 A;  1FZV A;  2GNN D;  2X1W A;  1AOC B;  2GYR B;  1WAQ A;  2QR0 O;  3QTK E;  2PJY A;  3QTK D;  1VPF A;  1XWD A;  2B0U A;  2VPF F;  3KFD C;  3BK3 B;  1QFW B;  2ARV A;  2H62 A;  1BND B;  2QCQ A;  1CZ8 V;  2R52 A;  2ASK A;  2X1W C;  2GNN A;  1REU A;  2FJH V;  1BJ1 V;  1KAT W;  3B4V E;  2VWE B;  2BHK A;  2P6A B;  1AGQ B;  1FL7 B;  2FJG V;  2QJA B;  2QR0 C;  2QR0 I;  3QTK A;  1HRP A;  3EVS B;  2GOO D;  2VPF D;  3KFD A;  2C7W A;  2QR0 J;  2QCW B;  1B8M A;  2GNN C;  2GYR E;  3FUB D;  1KLC B;  2GYZ A;  1CZ8 W;  1PDG B;  3MJG A;  2QJB B;  1TZH W;  2GH0 D;  1NYU D;  1BJ1 W;  3QTK C;  1NYS B;  2GOO A;  2GYR D;  2QJ9 A;  1FLT V;  1KLA B;  1MJV B;  1RV6 V;  1BTG B;  2VPF A;  3B4V F;  1QTY S;  1VPP V;  1TZI V;  1HCN A;  2XAC A;  1REW A;  1TGK A;  1KTZ A;  1S4Y B;  2R53 A;  3BMP A;  1AOC A;  2GYR F;  2VPF C;  1FL7 C;  1AGQ D;  1FL7 D;  3HH2 B;  1RV6 W;  3BK3 A;  1QFW A;  2X1X E;  2GH0 C;  1BND A;  1DZ7 A;  1WQ8 A;  1B98 A;  1WQ9 B;  2FJH W;  1FZV B;  2GYR C;  2XV7 A;  2X1W B;  2VWE A;  1TGJ A;  3EO1 C;  1HD4 A;  2VPF G;  3B4V A;  1AGQ A;  1FL7 A;  1QTY R;  1XWD E;  2FJG W;  2QJA A;  2QR0 P;  2H64 A;  1VPF B;  1XWD B;  2B0U B;  2ARV B;  2H62 B;  2QCQ B;  2QCW A;  1TFG A;  2R52 B;  2QR0 V;  1M4U L;  2ASK B;  1S4Y D;  2GNN B;  2QR0 U;  1KLC A;  1PDG A;  1KAT V;  2QJB A;  2GYR A;  1AGQ C;  1NT3 A;
...loading similar chains, please wait...
similar chains in the KnotProt database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the KnotProt database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...
How to cite
KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling