1AOCB

Japanese horseshoe crab coagulogen
Note, that the numbers in the matrix denote the consecutive residues in the loop, not the index of amino acids in the chain!
Knot K 2x -31 1x +31

  Help Knotting data interpretation Full screen
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
+ 31 9-53 45 1-8, 54-59 8 6 knot
Fingerprint Knot forming loop Loop type
K +31 Cys8 ... Cys10 <-> Cys95 ... Cys88 <-> Cys140 ... Cys161 <-> Cys60 ... Cys65 <-> Cys121 ... Cys134 <-> Cys172 ... Cys167 <-> Cys8 covalent
K -31
Chain closureAla1 <-> Phe175
... Cys170 <-> Cys127 ... Cys95 <-> Cys10 ... Cys60 <-> Cys161 ... Cys140 <-> Cys88 ... Cys75 <-> Cys168 ... Cys167 <-> Cys8 ... Ala1		 probabilistic
K -31
Chain closureAla1 <-> Phe175
... Cys170 <-> Cys127 ... Cys121 <-> Cys65 ... Cys60 <-> Cys161 ... Cys140 <-> Cys88 ... Cys75 <-> Cys168 ... Cys167 <-> Cys8 ... Ala1		 probabilistic
Chain Sequence
ADTNAPICLCDEPGVLGRTQIVTTEIKDKIEKAVEAVAQESGVSGRGFSIFSHHPVFRECGKYECRTVRPEHSRCYNFPPFTHFKSECPVSTRDCEPVFGYTVAGEFRVIVQAPRAGFRQCVWQHKCRFGSNSCGYNGRCTQQRSVVRLVTYNLEKDGFLCESFRTCCGCPCRSF
Cysteine knot

  Help Cysteine knot data interpretation Full screen
Loop Piercing
view details
127-c-134-b-172-c-170 88-b-140
Chain Sequence
ADTNAPICLCDEPGVLGRTQIVTTEIKDKIEKAVEAVAQESGVSGRGFSIFSHHPVFRECGKYECRTVRPEHSRCYNFPPFTHFKSECPVSTRDCEPVFGYTVAGEFRVIVQAPRAGFRQCVWQHKCRFGSNSCGYNGRCTQQRSVVRLVTYNLEKDGFLCESFRTCCGCPCRSF
sequence length 175
structure length 175
publication title Crystal structure of a coagulogen, the clotting protein from horseshoe crab: a structural homologue of nerve growth factor.
pubmed rcsb
molecule tags Coagulation factor
molecule keywords COAGULOGEN
ec nomenclature
pdb deposition date 1996-11-28
KnotProt deposition date 2018-09-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF02035 Coagulin Coagulin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.90.10 Mainly Beta Ribbon Cystine Knot Cytokines, subunit B Cystine-knot cytokines 1aocB00
2.10.90.10 Mainly Beta Ribbon Cystine Knot Cytokines, subunit B Cystine-knot cytokines 1aocB00
1FL7B 2GH0C 2X1WB 3B4VB 3QTKA 1FLTW 2VPFF 2XACB 2FJHW 2QCWA 2BHKA 1XWDD 2C7WB 2X1WA 3B4VA 3KFDB 2XACA 2GYRB 2X1WC 3EO1I 2C7WA 1QTYV 2V5EB 3KFDA 3BMPA 2GYRA 3KFDC 1VPPW 2GYRC 2XV7A 1BNDA 1HD4A 2H64A 2ARVB 2B0UB 1KATV 2QR0C 3EVSB 1LX5A 2ARVA 1BTGB 2B0UA 2GOOD 1NYUD 1TZHW 2VWEB 2P6AB 2QJBB 2VWEA 3QTKB 1B8MA 2P6AA 2QJBA 1HCNA 3FUBB 1WQ8A 2R53A 3QTKC 2GNND 3EO1C 3B4VE 1VPFD 2ASKB 1S4YB 1REWB 1BJ1V 1FZVA 1WAQA 1MJVA 2GOOA 2H62B 1BNDB 3BDYV 1PDGB 2ASKA 2TGIA 2GYRE 1REWA 1SGFB 2H62A 1PDGA 1TGJA 1B98A 2QJAA 3B4VF 1PDGC 2GYZA 2FJGV 1CZ8V 1XWDB 1AGQD 2GYRF 1AOCA 1XWDA 3MJGB 1HCNB 1ES7A 2VPFD 2R53B 2QR0V 3MJGA 1ES7C 2QR0O 2X1XE 3HH2B 3QTKE 1FZVB 1MJVB 3HH2A 1KLCA 1RV6V 1NYUB 1E9JA 1DZ7A 1VPPV 2QJ9A 2R52B 1AGQA 1HRPA 1FL7D 1QTYW 1KTZA 1AGQC 2QJAB 2X1WD 2VPFB 3QTKF 1BMPA 2R52A 3BK3B 2VPFA 2FJGW 1CZ8W 1KATW 1QFWA 2GNNB 2VPFC 1REUA 1AOCB 1VPFB 3BK3A 2VPFG 1KLAB 2QR0D 1XWDE 2GNNA 1QTYS 1VPFA 2GNNC 1FLTV 1KLAA 1VPFC 1WQ9A 2FJHV 1SGFY 1FL7A 1KLCB 1FL7C 3EO1L 1NT3A 2QJ9B 1RV6W 1AGQB 2GH0D 1HRPB 2QR0P 3QTKD 1BJ1W 2QR0J 1TGKA 3FUBD 1TZIV 1M4UL 1TFGA 2PJYA 1QFWB 2QCQB 1TZHV 2QR0U 2VPFE 3KFDD 1S4YD 2VPFH 1LXIA 1ZKZA 2GYRD 1QTYR 2QR0I 2QCQA 2ARPA 1WQ9B 2QCWB 1NYSB
chains in the KnotProt database with same CATH superfamily
1FL7B 2GH0C 2X1WB 3B4VB 3QTKA 1FLTW 2VPFF 2XACB 2FJHW 2QCWA 2BHKA 1XWDD 2C7WB 2X1WA 3B4VA 3KFDB 2XACA 2GYRB 2X1WC 3EO1I 2C7WA 1QTYV 2V5EB 3KFDA 3BMPA 2GYRA 3KFDC 1VPPW 2GYRC 2XV7A 1BNDA 1HD4A 2H64A 2ARVB 2B0UB 1KATV 2QR0C 3EVSB 1LX5A 2ARVA 1BTGB 2B0UA 2GOOD 1NYUD 1TZHW 2VWEB 2P6AB 2QJBB 2VWEA 3QTKB 1B8MA 2P6AA 2QJBA 1HCNA 3FUBB 1WQ8A 2R53A 3QTKC 2GNND 3EO1C 3B4VE 1VPFD 2ASKB 1S4YB 1REWB 1BJ1V 1FZVA 1WAQA 1MJVA 2GOOA 2H62B 1BNDB 3BDYV 1PDGB 2ASKA 2TGIA 2GYRE 1REWA 1SGFB 2H62A 1PDGA 1TGJA 1B98A 2QJAA 3B4VF 1PDGC 2GYZA 2FJGV 1CZ8V 1XWDB 1AGQD 2GYRF 1AOCA 1XWDA 3MJGB 1HCNB 1ES7A 2VPFD 2R53B 2QR0V 3MJGA 1ES7C 2QR0O 2X1XE 3HH2B 3QTKE 1FZVB 1MJVB 3HH2A 1KLCA 1RV6V 1NYUB 1E9JA 1DZ7A 1VPPV 2QJ9A 2R52B 1AGQA 1HRPA 1FL7D 1QTYW 1KTZA 1AGQC 2QJAB 2X1WD 2VPFB 3QTKF 1BMPA 2R52A 3BK3B 2VPFA 2FJGW 1CZ8W 1KATW 1QFWA 2GNNB 2VPFC 1REUA 1AOCB 1VPFB 3BK3A 2VPFG 1KLAB 2QR0D 1XWDE 2GNNA 1QTYS 1VPFA 2GNNC 1FLTV 1KLAA 1VPFC 1WQ9A 2FJHV 1SGFY 1FL7A 1KLCB 1FL7C 3EO1L 1NT3A 2QJ9B 1RV6W 1AGQB 2GH0D 1HRPB 2QR0P 3QTKD 1BJ1W 2QR0J 1TGKA 3FUBD 1TZIV 1M4UL 1TFGA 2PJYA 1QFWB 2QCQB 1TZHV 2QR0U 2VPFE 3KFDD 1S4YD 2VPFH 1LXIA 1ZKZA 2GYRD 1QTYR 2QR0I 2QCQA 2ARPA 1WQ9B 2QCWB 1NYSB
chains in the KnotProt database with same CATH topology
1FL7B 2GH0C 2X1WB 3B4VB 3QTKA 1FLTW 2VPFF 2XACB 2FJHW 2QCWA 2BHKA 1XWDD 2C7WB 2X1WA 3B4VA 3KFDB 2XACA 2GYRB 2X1WC 3EO1I 2C7WA 1QTYV 2V5EB 3KFDA 3BMPA 2GYRA 3KFDC 1VPPW 2GYRC 2XV7A 1BNDA 1HD4A 2H64A 2ARVB 2B0UB 1KATV 2QR0C 3EVSB 1LX5A 2ARVA 1BTGB 2B0UA 2GOOD 1NYUD 1TZHW 2VWEB 2P6AB 2QJBB 2VWEA 3QTKB 1B8MA 2P6AA 2QJBA 1HCNA 3FUBB 1WQ8A 2R53A 3QTKC 2GNND 3EO1C 3B4VE 1VPFD 2ASKB 1S4YB 1REWB 1BJ1V 1FZVA 1WAQA 1MJVA 2GOOA 2H62B 1BNDB 3BDYV 1PDGB 2ASKA 2TGIA 2GYRE 1REWA 1SGFB 2H62A 1PDGA 1TGJA 1B98A 2QJAA 3B4VF 1PDGC 2GYZA 2FJGV 1CZ8V 1XWDB 1AGQD 2GYRF 1AOCA 1XWDA 3MJGB 1HCNB 1ES7A 2VPFD 2R53B 2QR0V 3MJGA 1ES7C 2QR0O 2X1XE 3HH2B 3QTKE 1FZVB 1MJVB 3HH2A 1KLCA 1RV6V 1NYUB 1E9JA 1DZ7A 1VPPV 2QJ9A 2R52B 1AGQA 1HRPA 1FL7D 1QTYW 1KTZA 1AGQC 2QJAB 2X1WD 2VPFB 3QTKF 1BMPA 2R52A 3BK3B 2VPFA 2FJGW 1CZ8W 1KATW 1QFWA 2GNNB 2VPFC 1REUA 1AOCB 1VPFB 3BK3A 2VPFG 1KLAB 2QR0D 1XWDE 2GNNA 1QTYS 1VPFA 2GNNC 1FLTV 1KLAA 1VPFC 1WQ9A 2FJHV 1SGFY 1FL7A 1KLCB 1FL7C 3EO1L 1NT3A 2QJ9B 1RV6W 1AGQB 2GH0D 1HRPB 2QR0P 3QTKD 1BJ1W 2QR0J 1TGKA 3FUBD 1TZIV 1M4UL 1TFGA 2PJYA 1QFWB 2QCQB 1TZHV 2QR0U 2VPFE 3KFDD 1S4YD 2VPFH 1LXIA 1ZKZA 2GYRD 1QTYR 2QR0I 2QCQA 2ARPA 1WQ9B 2QCWB 1NYSB
chains in the KnotProt database with same CATH homology

  
#chains in the KnotProt database with same CATH superfamily
 1FL7 B;  2GH0 C;  2X1W B;  3B4V B;  3QTK A;  1FLT W;  2VPF F;  2XAC B;  2FJH W;  2QCW A;  2BHK A;  1XWD D;  2C7W B;  2X1W A;  3B4V A;  3KFD B;  2XAC A;  2GYR B;  2X1W C;  3EO1 I;  2C7W A;  1QTY V;  2V5E B;  3KFD A;  3BMP A;  2GYR A;  3KFD C;  1VPP W;  2GYR C;  2XV7 A;  1BND A;  1HD4 A;  2H64 A;  2ARV B;  2B0U B;  1KAT V;  2QR0 C;  3EVS B;  1LX5 A;  2ARV A;  1BTG B;  2B0U A;  2GOO D;  1NYU D;  1TZH W;  2VWE B;  2P6A B;  2QJB B;  2VWE A;  3QTK B;  1B8M A;  2P6A A;  2QJB A;  1HCN A;  3FUB B;  1WQ8 A;  2R53 A;  3QTK C;  2GNN D;  3EO1 C;  3B4V E;  1VPF D;  2ASK B;  1S4Y B;  1REW B;  1BJ1 V;  1FZV A;  1WAQ A;  1MJV A;  2GOO A;  2H62 B;  1BND B;  3BDY V;  1PDG B;  2ASK A;  2TGI A;  2GYR E;  1REW A;  1SGF B;  2H62 A;  1PDG A;  1TGJ A;  1B98 A;  2QJA A;  3B4V F;  1PDG C;  2GYZ A;  2FJG V;  1CZ8 V;  1XWD B;  1AGQ D;  2GYR F;  1AOC A;  1XWD A;  3MJG B;  1HCN B;  1ES7 A;  2VPF D;  2R53 B;  2QR0 V;  3MJG A;  1ES7 C;  2QR0 O;  2X1X E;  3HH2 B;  3QTK E;  1FZV B;  1MJV B;  3HH2 A;  1KLC A;  1RV6 V;  1NYU B;  1E9J A;  1DZ7 A;  1VPP V;  2QJ9 A;  2R52 B;  1AGQ A;  1HRP A;  1FL7 D;  1QTY W;  1KTZ A;  1AGQ C;  2QJA B;  2X1W D;  2VPF B;  3QTK F;  1BMP A;  2R52 A;  3BK3 B;  2VPF A;  2FJG W;  1CZ8 W;  1KAT W;  1QFW A;  2GNN B;  2VPF C;  1REU A;  1AOC B;  1VPF B;  3BK3 A;  2VPF G;  1KLA B;  2QR0 D;  1XWD E;  2GNN A;  1QTY S;  1VPF A;  2GNN C;  1FLT V;  1KLA A;  1VPF C;  1WQ9 A;  2FJH V;  1SGF Y;  1FL7 A;  1KLC B;  1FL7 C;  3EO1 L;  1NT3 A;  2QJ9 B;  1RV6 W;  1AGQ B;  2GH0 D;  1HRP B;  2QR0 P;  3QTK D;  1BJ1 W;  2QR0 J;  1TGK A;  3FUB D;  1TZI V;  1M4U L;  1TFG A;  2PJY A;  1QFW B;  2QCQ B;  1TZH V;  2QR0 U;  2VPF E;  3KFD D;  1S4Y D;  2VPF H;  1LXI A;  1ZKZ A;  2GYR D;  1QTY R;  2QR0 I;  2QCQ A;  2ARP A;  1WQ9 B;  2QCW B;  1NYS B; 
#chains in the KnotProt database with same CATH topology
 1FL7 B;  2GH0 C;  2X1W B;  3B4V B;  3QTK A;  1FLT W;  2VPF F;  2XAC B;  2FJH W;  2QCW A;  2BHK A;  1XWD D;  2C7W B;  2X1W A;  3B4V A;  3KFD B;  2XAC A;  2GYR B;  2X1W C;  3EO1 I;  2C7W A;  1QTY V;  2V5E B;  3KFD A;  3BMP A;  2GYR A;  3KFD C;  1VPP W;  2GYR C;  2XV7 A;  1BND A;  1HD4 A;  2H64 A;  2ARV B;  2B0U B;  1KAT V;  2QR0 C;  3EVS B;  1LX5 A;  2ARV A;  1BTG B;  2B0U A;  2GOO D;  1NYU D;  1TZH W;  2VWE B;  2P6A B;  2QJB B;  2VWE A;  3QTK B;  1B8M A;  2P6A A;  2QJB A;  1HCN A;  3FUB B;  1WQ8 A;  2R53 A;  3QTK C;  2GNN D;  3EO1 C;  3B4V E;  1VPF D;  2ASK B;  1S4Y B;  1REW B;  1BJ1 V;  1FZV A;  1WAQ A;  1MJV A;  2GOO A;  2H62 B;  1BND B;  3BDY V;  1PDG B;  2ASK A;  2TGI A;  2GYR E;  1REW A;  1SGF B;  2H62 A;  1PDG A;  1TGJ A;  1B98 A;  2QJA A;  3B4V F;  1PDG C;  2GYZ A;  2FJG V;  1CZ8 V;  1XWD B;  1AGQ D;  2GYR F;  1AOC A;  1XWD A;  3MJG B;  1HCN B;  1ES7 A;  2VPF D;  2R53 B;  2QR0 V;  3MJG A;  1ES7 C;  2QR0 O;  2X1X E;  3HH2 B;  3QTK E;  1FZV B;  1MJV B;  3HH2 A;  1KLC A;  1RV6 V;  1NYU B;  1E9J A;  1DZ7 A;  1VPP V;  2QJ9 A;  2R52 B;  1AGQ A;  1HRP A;  1FL7 D;  1QTY W;  1KTZ A;  1AGQ C;  2QJA B;  2X1W D;  2VPF B;  3QTK F;  1BMP A;  2R52 A;  3BK3 B;  2VPF A;  2FJG W;  1CZ8 W;  1KAT W;  1QFW A;  2GNN B;  2VPF C;  1REU A;  1AOC B;  1VPF B;  3BK3 A;  2VPF G;  1KLA B;  2QR0 D;  1XWD E;  2GNN A;  1QTY S;  1VPF A;  2GNN C;  1FLT V;  1KLA A;  1VPF C;  1WQ9 A;  2FJH V;  1SGF Y;  1FL7 A;  1KLC B;  1FL7 C;  3EO1 L;  1NT3 A;  2QJ9 B;  1RV6 W;  1AGQ B;  2GH0 D;  1HRP B;  2QR0 P;  3QTK D;  1BJ1 W;  2QR0 J;  1TGK A;  3FUB D;  1TZI V;  1M4U L;  1TFG A;  2PJY A;  1QFW B;  2QCQ B;  1TZH V;  2QR0 U;  2VPF E;  3KFD D;  1S4Y D;  2VPF H;  1LXI A;  1ZKZ A;  2GYR D;  1QTY R;  2QR0 I;  2QCQ A;  2ARP A;  1WQ9 B;  2QCW B;  1NYS B; 
#chains in the KnotProt database with same CATH homology
 1FL7 B;  2GH0 C;  2X1W B;  3B4V B;  3QTK A;  1FLT W;  2VPF F;  2XAC B;  2FJH W;  2QCW A;  2BHK A;  1XWD D;  2C7W B;  2X1W A;  3B4V A;  3KFD B;  2XAC A;  2GYR B;  2X1W C;  3EO1 I;  2C7W A;  1QTY V;  2V5E B;  3KFD A;  3BMP A;  2GYR A;  3KFD C;  1VPP W;  2GYR C;  2XV7 A;  1BND A;  1HD4 A;  2H64 A;  2ARV B;  2B0U B;  1KAT V;  2QR0 C;  3EVS B;  1LX5 A;  2ARV A;  1BTG B;  2B0U A;  2GOO D;  1NYU D;  1TZH W;  2VWE B;  2P6A B;  2QJB B;  2VWE A;  3QTK B;  1B8M A;  2P6A A;  2QJB A;  1HCN A;  3FUB B;  1WQ8 A;  2R53 A;  3QTK C;  2GNN D;  3EO1 C;  3B4V E;  1VPF D;  2ASK B;  1S4Y B;  1REW B;  1BJ1 V;  1FZV A;  1WAQ A;  1MJV A;  2GOO A;  2H62 B;  1BND B;  3BDY V;  1PDG B;  2ASK A;  2TGI A;  2GYR E;  1REW A;  1SGF B;  2H62 A;  1PDG A;  1TGJ A;  1B98 A;  2QJA A;  3B4V F;  1PDG C;  2GYZ A;  2FJG V;  1CZ8 V;  1XWD B;  1AGQ D;  2GYR F;  1AOC A;  1XWD A;  3MJG B;  1HCN B;  1ES7 A;  2VPF D;  2R53 B;  2QR0 V;  3MJG A;  1ES7 C;  2QR0 O;  2X1X E;  3HH2 B;  3QTK E;  1FZV B;  1MJV B;  3HH2 A;  1KLC A;  1RV6 V;  1NYU B;  1E9J A;  1DZ7 A;  1VPP V;  2QJ9 A;  2R52 B;  1AGQ A;  1HRP A;  1FL7 D;  1QTY W;  1KTZ A;  1AGQ C;  2QJA B;  2X1W D;  2VPF B;  3QTK F;  1BMP A;  2R52 A;  3BK3 B;  2VPF A;  2FJG W;  1CZ8 W;  1KAT W;  1QFW A;  2GNN B;  2VPF C;  1REU A;  1AOC B;  1VPF B;  3BK3 A;  2VPF G;  1KLA B;  2QR0 D;  1XWD E;  2GNN A;  1QTY S;  1VPF A;  2GNN C;  1FLT V;  1KLA A;  1VPF C;  1WQ9 A;  2FJH V;  1SGF Y;  1FL7 A;  1KLC B;  1FL7 C;  3EO1 L;  1NT3 A;  2QJ9 B;  1RV6 W;  1AGQ B;  2GH0 D;  1HRP B;  2QR0 P;  3QTK D;  1BJ1 W;  2QR0 J;  1TGK A;  3FUB D;  1TZI V;  1M4U L;  1TFG A;  2PJY A;  1QFW B;  2QCQ B;  1TZH V;  2QR0 U;  2VPF E;  3KFD D;  1S4Y D;  2VPF H;  1LXI A;  1ZKZ A;  2GYR D;  1QTY R;  2QR0 I;  2QCQ A;  2ARP A;  1WQ9 B;  2QCW B;  1NYS B;
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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