1AOCA

Japanese horseshoe crab coagulogen
Note, that the numbers in the matrix denote the consecutive residues in the loop, not the index of amino acids in the chain!
Knot K 2x -31 1x +31

  Help Knotting data interpretation Full screen
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
+ 31 10-57 48 1-9, 58-59 9 2 knot
Fingerprint Knot forming loop Loop type
K +31 Cys8 <-> Cys167 ... Cys172 <-> Cys134 ... Cys121 <-> Cys65 ... Cys60 <-> Cys161 ... Cys140 <-> Cys88 ... Cys95 <-> Cys10 ... Cys8 covalent
K -31
Chain closureAla1 <-> Phe175
... Cys170 <-> Cys127 ... Cys95 <-> Cys10 ... Cys60 <-> Cys161 ... Cys140 <-> Cys88 ... Cys75 <-> Cys168 ... Cys167 <-> Cys8 ... Ala1		 probabilistic
K -31
Chain closureAla1 <-> Phe175
... Cys170 <-> Cys127 ... Cys121 <-> Cys65 ... Cys60 <-> Cys161 ... Cys140 <-> Cys88 ... Cys75 <-> Cys168 ... Cys167 <-> Cys8 ... Ala1		 probabilistic
Chain Sequence
ADTNAPICLCDEPGVLGRTQIVTTEIKDKIEKAVEAVAQESGVSGRGFSIFSHHPVFRECGKYECRTVRPEHSRCYNFPPFTHFKSECPVSTRDCEPVFGYTVAGEFRVIVQAPRAGFRQCVWQHKCRFGSNSCGYNGRCTQQRSVVRLVTYNLEKDGFLCESFRTCCGCPCRSF
Cysteine knot

  Help Cysteine knot data interpretation Full screen
Loop Piercing
view details
127-c-134-b-172-c-170 88-b-140
Chain Sequence
ADTNAPICLCDEPGVLGRTQIVTTEIKDKIEKAVEAVAQESGVSGRGFSIFSHHPVFRECGKYECRTVRPEHSRCYNFPPFTHFKSECPVSTRDCEPVFGYTVAGEFRVIVQAPRAGFRQCVWQHKCRFGSNSCGYNGRCTQQRSVVRLVTYNLEKDGFLCESFRTCCGCPCRSF
sequence length 175
structure length 175
publication title Crystal structure of a coagulogen, the clotting protein from horseshoe crab: a structural homologue of nerve growth factor.
pubmed rcsb
molecule tags Coagulation factor
molecule keywords COAGULOGEN
total genus Genus: 40
ec nomenclature
pdb deposition date 1996-11-28
KnotProt deposition date 2018-10-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02035 Coagulin Coagulin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.90.10 Mainly Beta Ribbon Cystine Knot Cytokines, subunit B Cystine-knot cytokines 1aocA00
2.10.90.10 Mainly Beta Ribbon Cystine Knot Cytokines, subunit B Cystine-knot cytokines 1aocA00
3B4VA 1SGFB 2GYZA 1REWA 1QTYV 1VPPW 1E9JA 2QCQA 3BDYV 1FZVB 3EO1I 3BK3B 1AGQC 1VPFC 1WQ9B 1TZIV 3B4VF 1HRPB 1QFWB 3EO1L 2GYRD 1FL7A 2VPFD 2VPFB 1S4YD 2QR0V 2XV7A 1HCNB 1VPPV 2QR0I 1NYUB 2H62A 1FL7D 2GOOD 1XWDA 3QTKD 3MJGB 2B0UA 1KLCB 2QR0D 2R52A 2X1WB 1MJVB 2XACA 1SGFY 3KFDB 1NT3A 1AOCA 1FZVA 1B98A 1KTZA 2FJGW 1FL7C 2QCWA 3B4VE 2QR0O 1KATW 1B8MA 1QFWA 1WAQA 2GYRA 2VPFA 1KLAB 2GNNB 1REUA 2GH0D 1HCNA 2QJ9A 2C7WB 2H64A 2ARVA 1BJ1W 2P6AA 2FJGV 2GOOA 1KATV 3MJGA 3QTKA 2ASKB 2GYRF 1KLCA 2VWEA 2X1WA 1NYUD 1MJVA 2QJBB 1TFGA 1PDGA 1LXIA 2R53A 2GH0C 3FUBB 1XWDE 1BNDA 1TGJA 1AGQB 1BJ1V 1ES7A 2X1WD 1CZ8W 2FJHW 1HD4A 2GYRC 2VPFC 2X1XE 3EO1C 3QTKF 1QTYR 2QR0P 3KFDD 1FLTW 3EVSB 1KLAA 3BK3A 1BMPA 3B4VB 3HH2B 1WQ9A 3QTKC 1CZ8V 1HRPA 2QR0C 2FJHV 2X1WC 2GYRE 2GNND 2VPFE 1PDGC 1FLTV 1ES7C 2QJBA 3BMPA 2BHKA 1NYSB 1RV6W 3QTKE 2VPFF 3KFDA 3FUBD 1LX5A 1AGQD 1XWDB 1BTGB 1VPFB 2ARPA 2B0UB 2R52B 2XACB 1DZ7A 2QJAB 1RV6V 1M4UL 3HH2A 2QR0J 1AOCB 2GNNA 2PJYA 2C7WA 1ZKZA 2QCWB 1REWB 1TZHW 3KFDC 2QCQB 2GYRB 2TGIA 2VPFG 1S4YB 2ASKA 2QJ9B 2QR0U 2ARVB 2P6AB 1FL7B 1AGQA 1QTYS 1VPFA 3QTKB 1QTYW 2V5EB 2VWEB 1TZHV 2GNNC 2QJAA 2H62B 2VPFH 1PDGB 2R53B 1XWDD 1TGKA 1WQ8A 1BNDB 1VPFD
chains in the KnotProt database with same CATH superfamily
3B4VA 1SGFB 2GYZA 1REWA 1QTYV 1VPPW 1E9JA 2QCQA 3BDYV 1FZVB 3EO1I 3BK3B 1AGQC 1VPFC 1WQ9B 1TZIV 3B4VF 1HRPB 1QFWB 3EO1L 2GYRD 1FL7A 2VPFD 2VPFB 1S4YD 2QR0V 2XV7A 1HCNB 1VPPV 2QR0I 1NYUB 2H62A 1FL7D 2GOOD 1XWDA 3QTKD 3MJGB 2B0UA 1KLCB 2QR0D 2R52A 2X1WB 1MJVB 2XACA 1SGFY 3KFDB 1NT3A 1AOCA 1FZVA 1B98A 1KTZA 2FJGW 1FL7C 2QCWA 3B4VE 2QR0O 1KATW 1B8MA 1QFWA 1WAQA 2GYRA 2VPFA 1KLAB 2GNNB 1REUA 2GH0D 1HCNA 2QJ9A 2C7WB 2H64A 2ARVA 1BJ1W 2P6AA 2FJGV 2GOOA 1KATV 3MJGA 3QTKA 2ASKB 2GYRF 1KLCA 2VWEA 2X1WA 1NYUD 1MJVA 2QJBB 1TFGA 1PDGA 1LXIA 2R53A 2GH0C 3FUBB 1XWDE 1BNDA 1TGJA 1AGQB 1BJ1V 1ES7A 2X1WD 1CZ8W 2FJHW 1HD4A 2GYRC 2VPFC 2X1XE 3EO1C 3QTKF 1QTYR 2QR0P 3KFDD 1FLTW 3EVSB 1KLAA 3BK3A 1BMPA 3B4VB 3HH2B 1WQ9A 3QTKC 1CZ8V 1HRPA 2QR0C 2FJHV 2X1WC 2GYRE 2GNND 2VPFE 1PDGC 1FLTV 1ES7C 2QJBA 3BMPA 2BHKA 1NYSB 1RV6W 3QTKE 2VPFF 3KFDA 3FUBD 1LX5A 1AGQD 1XWDB 1BTGB 1VPFB 2ARPA 2B0UB 2R52B 2XACB 1DZ7A 2QJAB 1RV6V 1M4UL 3HH2A 2QR0J 1AOCB 2GNNA 2PJYA 2C7WA 1ZKZA 2QCWB 1REWB 1TZHW 3KFDC 2QCQB 2GYRB 2TGIA 2VPFG 1S4YB 2ASKA 2QJ9B 2QR0U 2ARVB 2P6AB 1FL7B 1AGQA 1QTYS 1VPFA 3QTKB 1QTYW 2V5EB 2VWEB 1TZHV 2GNNC 2QJAA 2H62B 2VPFH 1PDGB 2R53B 1XWDD 1TGKA 1WQ8A 1BNDB 1VPFD
chains in the KnotProt database with same CATH topology
3B4VA 1SGFB 2GYZA 1REWA 1QTYV 1VPPW 1E9JA 2QCQA 3BDYV 1FZVB 3EO1I 3BK3B 1AGQC 1VPFC 1WQ9B 1TZIV 3B4VF 1HRPB 1QFWB 3EO1L 2GYRD 1FL7A 2VPFD 2VPFB 1S4YD 2QR0V 2XV7A 1HCNB 1VPPV 2QR0I 1NYUB 2H62A 1FL7D 2GOOD 1XWDA 3QTKD 3MJGB 2B0UA 1KLCB 2QR0D 2R52A 2X1WB 1MJVB 2XACA 1SGFY 3KFDB 1NT3A 1AOCA 1FZVA 1B98A 1KTZA 2FJGW 1FL7C 2QCWA 3B4VE 2QR0O 1KATW 1B8MA 1QFWA 1WAQA 2GYRA 2VPFA 1KLAB 2GNNB 1REUA 2GH0D 1HCNA 2QJ9A 2C7WB 2H64A 2ARVA 1BJ1W 2P6AA 2FJGV 2GOOA 1KATV 3MJGA 3QTKA 2ASKB 2GYRF 1KLCA 2VWEA 2X1WA 1NYUD 1MJVA 2QJBB 1TFGA 1PDGA 1LXIA 2R53A 2GH0C 3FUBB 1XWDE 1BNDA 1TGJA 1AGQB 1BJ1V 1ES7A 2X1WD 1CZ8W 2FJHW 1HD4A 2GYRC 2VPFC 2X1XE 3EO1C 3QTKF 1QTYR 2QR0P 3KFDD 1FLTW 3EVSB 1KLAA 3BK3A 1BMPA 3B4VB 3HH2B 1WQ9A 3QTKC 1CZ8V 1HRPA 2QR0C 2FJHV 2X1WC 2GYRE 2GNND 2VPFE 1PDGC 1FLTV 1ES7C 2QJBA 3BMPA 2BHKA 1NYSB 1RV6W 3QTKE 2VPFF 3KFDA 3FUBD 1LX5A 1AGQD 1XWDB 1BTGB 1VPFB 2ARPA 2B0UB 2R52B 2XACB 1DZ7A 2QJAB 1RV6V 1M4UL 3HH2A 2QR0J 1AOCB 2GNNA 2PJYA 2C7WA 1ZKZA 2QCWB 1REWB 1TZHW 3KFDC 2QCQB 2GYRB 2TGIA 2VPFG 1S4YB 2ASKA 2QJ9B 2QR0U 2ARVB 2P6AB 1FL7B 1AGQA 1QTYS 1VPFA 3QTKB 1QTYW 2V5EB 2VWEB 1TZHV 2GNNC 2QJAA 2H62B 2VPFH 1PDGB 2R53B 1XWDD 1TGKA 1WQ8A 1BNDB 1VPFD
chains in the KnotProt database with same CATH homology

  
#chains in the KnotProt database with same CATH superfamily
 3B4V A;  1SGF B;  2GYZ A;  1REW A;  1QTY V;  1VPP W;  1E9J A;  2QCQ A;  3BDY V;  1FZV B;  3EO1 I;  3BK3 B;  1AGQ C;  1VPF C;  1WQ9 B;  1TZI V;  3B4V F;  1HRP B;  1QFW B;  3EO1 L;  2GYR D;  1FL7 A;  2VPF D;  2VPF B;  1S4Y D;  2QR0 V;  2XV7 A;  1HCN B;  1VPP V;  2QR0 I;  1NYU B;  2H62 A;  1FL7 D;  2GOO D;  1XWD A;  3QTK D;  3MJG B;  2B0U A;  1KLC B;  2QR0 D;  2R52 A;  2X1W B;  1MJV B;  2XAC A;  1SGF Y;  3KFD B;  1NT3 A;  1AOC A;  1FZV A;  1B98 A;  1KTZ A;  2FJG W;  1FL7 C;  2QCW A;  3B4V E;  2QR0 O;  1KAT W;  1B8M A;  1QFW A;  1WAQ A;  2GYR A;  2VPF A;  1KLA B;  2GNN B;  1REU A;  2GH0 D;  1HCN A;  2QJ9 A;  2C7W B;  2H64 A;  2ARV A;  1BJ1 W;  2P6A A;  2FJG V;  2GOO A;  1KAT V;  3MJG A;  3QTK A;  2ASK B;  2GYR F;  1KLC A;  2VWE A;  2X1W A;  1NYU D;  1MJV A;  2QJB B;  1TFG A;  1PDG A;  1LXI A;  2R53 A;  2GH0 C;  3FUB B;  1XWD E;  1BND A;  1TGJ A;  1AGQ B;  1BJ1 V;  1ES7 A;  2X1W D;  1CZ8 W;  2FJH W;  1HD4 A;  2GYR C;  2VPF C;  2X1X E;  3EO1 C;  3QTK F;  1QTY R;  2QR0 P;  3KFD D;  1FLT W;  3EVS B;  1KLA A;  3BK3 A;  1BMP A;  3B4V B;  3HH2 B;  1WQ9 A;  3QTK C;  1CZ8 V;  1HRP A;  2QR0 C;  2FJH V;  2X1W C;  2GYR E;  2GNN D;  2VPF E;  1PDG C;  1FLT V;  1ES7 C;  2QJB A;  3BMP A;  2BHK A;  1NYS B;  1RV6 W;  3QTK E;  2VPF F;  3KFD A;  3FUB D;  1LX5 A;  1AGQ D;  1XWD B;  1BTG B;  1VPF B;  2ARP A;  2B0U B;  2R52 B;  2XAC B;  1DZ7 A;  2QJA B;  1RV6 V;  1M4U L;  3HH2 A;  2QR0 J;  1AOC B;  2GNN A;  2PJY A;  2C7W A;  1ZKZ A;  2QCW B;  1REW B;  1TZH W;  3KFD C;  2QCQ B;  2GYR B;  2TGI A;  2VPF G;  1S4Y B;  2ASK A;  2QJ9 B;  2QR0 U;  2ARV B;  2P6A B;  1FL7 B;  1AGQ A;  1QTY S;  1VPF A;  3QTK B;  1QTY W;  2V5E B;  2VWE B;  1TZH V;  2GNN C;  2QJA A;  2H62 B;  2VPF H;  1PDG B;  2R53 B;  1XWD D;  1TGK A;  1WQ8 A;  1BND B;  1VPF D; 
#chains in the KnotProt database with same CATH topology
 3B4V A;  1SGF B;  2GYZ A;  1REW A;  1QTY V;  1VPP W;  1E9J A;  2QCQ A;  3BDY V;  1FZV B;  3EO1 I;  3BK3 B;  1AGQ C;  1VPF C;  1WQ9 B;  1TZI V;  3B4V F;  1HRP B;  1QFW B;  3EO1 L;  2GYR D;  1FL7 A;  2VPF D;  2VPF B;  1S4Y D;  2QR0 V;  2XV7 A;  1HCN B;  1VPP V;  2QR0 I;  1NYU B;  2H62 A;  1FL7 D;  2GOO D;  1XWD A;  3QTK D;  3MJG B;  2B0U A;  1KLC B;  2QR0 D;  2R52 A;  2X1W B;  1MJV B;  2XAC A;  1SGF Y;  3KFD B;  1NT3 A;  1AOC A;  1FZV A;  1B98 A;  1KTZ A;  2FJG W;  1FL7 C;  2QCW A;  3B4V E;  2QR0 O;  1KAT W;  1B8M A;  1QFW A;  1WAQ A;  2GYR A;  2VPF A;  1KLA B;  2GNN B;  1REU A;  2GH0 D;  1HCN A;  2QJ9 A;  2C7W B;  2H64 A;  2ARV A;  1BJ1 W;  2P6A A;  2FJG V;  2GOO A;  1KAT V;  3MJG A;  3QTK A;  2ASK B;  2GYR F;  1KLC A;  2VWE A;  2X1W A;  1NYU D;  1MJV A;  2QJB B;  1TFG A;  1PDG A;  1LXI A;  2R53 A;  2GH0 C;  3FUB B;  1XWD E;  1BND A;  1TGJ A;  1AGQ B;  1BJ1 V;  1ES7 A;  2X1W D;  1CZ8 W;  2FJH W;  1HD4 A;  2GYR C;  2VPF C;  2X1X E;  3EO1 C;  3QTK F;  1QTY R;  2QR0 P;  3KFD D;  1FLT W;  3EVS B;  1KLA A;  3BK3 A;  1BMP A;  3B4V B;  3HH2 B;  1WQ9 A;  3QTK C;  1CZ8 V;  1HRP A;  2QR0 C;  2FJH V;  2X1W C;  2GYR E;  2GNN D;  2VPF E;  1PDG C;  1FLT V;  1ES7 C;  2QJB A;  3BMP A;  2BHK A;  1NYS B;  1RV6 W;  3QTK E;  2VPF F;  3KFD A;  3FUB D;  1LX5 A;  1AGQ D;  1XWD B;  1BTG B;  1VPF B;  2ARP A;  2B0U B;  2R52 B;  2XAC B;  1DZ7 A;  2QJA B;  1RV6 V;  1M4U L;  3HH2 A;  2QR0 J;  1AOC B;  2GNN A;  2PJY A;  2C7W A;  1ZKZ A;  2QCW B;  1REW B;  1TZH W;  3KFD C;  2QCQ B;  2GYR B;  2TGI A;  2VPF G;  1S4Y B;  2ASK A;  2QJ9 B;  2QR0 U;  2ARV B;  2P6A B;  1FL7 B;  1AGQ A;  1QTY S;  1VPF A;  3QTK B;  1QTY W;  2V5E B;  2VWE B;  1TZH V;  2GNN C;  2QJA A;  2H62 B;  2VPF H;  1PDG B;  2R53 B;  1XWD D;  1TGK A;  1WQ8 A;  1BND B;  1VPF D; 
#chains in the KnotProt database with same CATH homology
 3B4V A;  1SGF B;  2GYZ A;  1REW A;  1QTY V;  1VPP W;  1E9J A;  2QCQ A;  3BDY V;  1FZV B;  3EO1 I;  3BK3 B;  1AGQ C;  1VPF C;  1WQ9 B;  1TZI V;  3B4V F;  1HRP B;  1QFW B;  3EO1 L;  2GYR D;  1FL7 A;  2VPF D;  2VPF B;  1S4Y D;  2QR0 V;  2XV7 A;  1HCN B;  1VPP V;  2QR0 I;  1NYU B;  2H62 A;  1FL7 D;  2GOO D;  1XWD A;  3QTK D;  3MJG B;  2B0U A;  1KLC B;  2QR0 D;  2R52 A;  2X1W B;  1MJV B;  2XAC A;  1SGF Y;  3KFD B;  1NT3 A;  1AOC A;  1FZV A;  1B98 A;  1KTZ A;  2FJG W;  1FL7 C;  2QCW A;  3B4V E;  2QR0 O;  1KAT W;  1B8M A;  1QFW A;  1WAQ A;  2GYR A;  2VPF A;  1KLA B;  2GNN B;  1REU A;  2GH0 D;  1HCN A;  2QJ9 A;  2C7W B;  2H64 A;  2ARV A;  1BJ1 W;  2P6A A;  2FJG V;  2GOO A;  1KAT V;  3MJG A;  3QTK A;  2ASK B;  2GYR F;  1KLC A;  2VWE A;  2X1W A;  1NYU D;  1MJV A;  2QJB B;  1TFG A;  1PDG A;  1LXI A;  2R53 A;  2GH0 C;  3FUB B;  1XWD E;  1BND A;  1TGJ A;  1AGQ B;  1BJ1 V;  1ES7 A;  2X1W D;  1CZ8 W;  2FJH W;  1HD4 A;  2GYR C;  2VPF C;  2X1X E;  3EO1 C;  3QTK F;  1QTY R;  2QR0 P;  3KFD D;  1FLT W;  3EVS B;  1KLA A;  3BK3 A;  1BMP A;  3B4V B;  3HH2 B;  1WQ9 A;  3QTK C;  1CZ8 V;  1HRP A;  2QR0 C;  2FJH V;  2X1W C;  2GYR E;  2GNN D;  2VPF E;  1PDG C;  1FLT V;  1ES7 C;  2QJB A;  3BMP A;  2BHK A;  1NYS B;  1RV6 W;  3QTK E;  2VPF F;  3KFD A;  3FUB D;  1LX5 A;  1AGQ D;  1XWD B;  1BTG B;  1VPF B;  2ARP A;  2B0U B;  2R52 B;  2XAC B;  1DZ7 A;  2QJA B;  1RV6 V;  1M4U L;  3HH2 A;  2QR0 J;  1AOC B;  2GNN A;  2PJY A;  2C7W A;  1ZKZ A;  2QCW B;  1REW B;  1TZH W;  3KFD C;  2QCQ B;  2GYR B;  2TGI A;  2VPF G;  1S4Y B;  2ASK A;  2QJ9 B;  2QR0 U;  2ARV B;  2P6A B;  1FL7 B;  1AGQ A;  1QTY S;  1VPF A;  3QTK B;  1QTY W;  2V5E B;  2VWE B;  1TZH V;  2GNN C;  2QJA A;  2H62 B;  2VPF H;  1PDG B;  2R53 B;  1XWD D;  1TGK A;  1WQ8 A;  1BND B;  1VPF D;
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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