1AOCA

Japanese horseshoe crab coagulogen
Note, that the numbers in the matrix denote the consecutive residues in the loop, not the index of amino acids in the chain!
Knot K 2x -31 1x +31

  Help Knotting data interpretation Full screen
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
+ 31 10-57 48 1-9, 58-59 9 2 knot
Fingerprint Knot forming loop Loop type
K +31 Cys8 <-> Cys167 ... Cys172 <-> Cys134 ... Cys121 <-> Cys65 ... Cys60 <-> Cys161 ... Cys140 <-> Cys88 ... Cys95 <-> Cys10 ... Cys8 covalent
K -31
Chain closureAla1 <-> Phe175
... Cys170 <-> Cys127 ... Cys95 <-> Cys10 ... Cys60 <-> Cys161 ... Cys140 <-> Cys88 ... Cys75 <-> Cys168 ... Cys167 <-> Cys8 ... Ala1		 probabilistic
K -31
Chain closureAla1 <-> Phe175
... Cys170 <-> Cys127 ... Cys121 <-> Cys65 ... Cys60 <-> Cys161 ... Cys140 <-> Cys88 ... Cys75 <-> Cys168 ... Cys167 <-> Cys8 ... Ala1		 probabilistic
Chain Sequence
ADTNAPICLCDEPGVLGRTQIVTTEIKDKIEKAVEAVAQESGVSGRGFSIFSHHPVFRECGKYECRTVRPEHSRCYNFPPFTHFKSECPVSTRDCEPVFGYTVAGEFRVIVQAPRAGFRQCVWQHKCRFGSNSCGYNGRCTQQRSVVRLVTYNLEKDGFLCESFRTCCGCPCRSF
Cysteine knot

  Help Cysteine knot data interpretation Full screen
Loop Piercing
view details
127-c-134-b-172-c-170 88-b-140
Chain Sequence
ADTNAPICLCDEPGVLGRTQIVTTEIKDKIEKAVEAVAQESGVSGRGFSIFSHHPVFRECGKYECRTVRPEHSRCYNFPPFTHFKSECPVSTRDCEPVFGYTVAGEFRVIVQAPRAGFRQCVWQHKCRFGSNSCGYNGRCTQQRSVVRLVTYNLEKDGFLCESFRTCCGCPCRSF
sequence length 175
structure length 175
publication title Crystal structure of a coagulogen, the clotting protein from horseshoe crab: a structural homologue of nerve growth factor.
pubmed rcsb
molecule tags Coagulation factor
molecule keywords COAGULOGEN
total genus Genus: 40
ec nomenclature
pdb deposition date 1996-11-28
KnotProt deposition date 2018-10-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02035 Coagulin Coagulin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.90.10 Mainly Beta Ribbon Cystine Knot Cytokines, subunit B Cystine-knot cytokines 1aocA00
2.10.90.10 Mainly Beta Ribbon Cystine Knot Cytokines, subunit B Cystine-knot cytokines 1aocA00
3EVSB 1VPPV 1XWDE 2GYRD 2VPFG 2X1WD 1BMPA 1NYUD 2GYRC 3BK3B 2QCQA 2X1WC 2QCQB 1VPFB 2FJHW 1QFWB 3HH2A 2GYRF 3HH2B 2QR0D 2R52A 2GYRE 2R52B 3EO1C 2QR0C 1BNDA 1REUA 2ARVA 1BNDB 2VPFF 2ARVB 2B0UA 2QCWB 3QTKF 2QR0U 2XACA 3QTKE 2X1XE 2XACB 1S4YD 1QTYS 3BMPA 2H62A 1SGFB 2H62B 1NYSB 2R53B 1FZVA 1AGQB 1FZVB 2QR0V 2GNNA 1WQ8A 1NT3A 2GNNB 2QJBA 2QJBB 1LXIA 2TGIA 3BK3A 1TZIV 1BTGB 1VPFA 1TZHW 1QFWA 1WQ9A 2VPFD 1WQ9B 3QTKD 2FJHV 3KFDB 3B4VA 3B4VB 1BJ1W 2VPFC 1QTYR 1KLCA 2PJYA 3QTKC 1KLCB 1MJVA 2GOOA 1MJVB 1RV6W 2QCWA 2FJGW 2VPFE 2ARPA 3FUBB 1FL7A 1FL7B 1XWDA 1XWDB 1PDGB 1B8MA 1FLTW 2R53A 1AGQA 1AOCA 1AOCB 1TGJA 1KLAB 3EO1I 1KATW 2GYRB 2QR0I 2V5EB 2X1WA 2X1WB 1VPFC 2P6AB 1REWA 1CZ8W 1NYUB 1LX5A 1REWB 1QTYW 2XV7A 2ASKA 1TZHV 1ES7A 2ASKB 2QR0J 3KFDA 1HRPB 3B4VF 1BJ1V 2C7WA 3MJGB 2C7WB 2VWEB 2GYZA 1TFGA 1WAQA 2GH0D 2QJ9A 1RV6V 2QJ9B 2FJGV 1E9JA 2GH0C 1PDGA 1S4YB 2GNND 1AGQC 1PDGC 1DZ7A 1VPPW 2VPFH 1FLTV 2GNNC 1HD4A 2QR0P 1KLAA 1SGFY 1KTZA 1VPFD 2GYRA 1KATV 1TGKA 2QJAA 3KFDD 1HCNA 2QJAB 2P6AA 1HCNB 3BDYV 3EO1L 2BHKA 2H64A 1CZ8V 1ES7C 3KFDC 2GOOD 1QTYV 2VPFA 1ZKZA 2VPFB 3QTKA 1HRPA 3QTKB 2B0UB 3FUBD 3MJGA 1FL7D 2QR0O 2VWEA 1XWDD 3B4VE 1B98A 1FL7C 1M4UL 1AGQD
chains in the KnotProt database with same CATH superfamily
3EVSB 1VPPV 1XWDE 2GYRD 2VPFG 2X1WD 1BMPA 1NYUD 2GYRC 3BK3B 2QCQA 2X1WC 2QCQB 1VPFB 2FJHW 1QFWB 3HH2A 2GYRF 3HH2B 2QR0D 2R52A 2GYRE 2R52B 3EO1C 2QR0C 1BNDA 1REUA 2ARVA 1BNDB 2VPFF 2ARVB 2B0UA 2QCWB 3QTKF 2QR0U 2XACA 3QTKE 2X1XE 2XACB 1S4YD 1QTYS 3BMPA 2H62A 1SGFB 2H62B 1NYSB 2R53B 1FZVA 1AGQB 1FZVB 2QR0V 2GNNA 1WQ8A 1NT3A 2GNNB 2QJBA 2QJBB 1LXIA 2TGIA 3BK3A 1TZIV 1BTGB 1VPFA 1TZHW 1QFWA 1WQ9A 2VPFD 1WQ9B 3QTKD 2FJHV 3KFDB 3B4VA 3B4VB 1BJ1W 2VPFC 1QTYR 1KLCA 2PJYA 3QTKC 1KLCB 1MJVA 2GOOA 1MJVB 1RV6W 2QCWA 2FJGW 2VPFE 2ARPA 3FUBB 1FL7A 1FL7B 1XWDA 1XWDB 1PDGB 1B8MA 1FLTW 2R53A 1AGQA 1AOCA 1AOCB 1TGJA 1KLAB 3EO1I 1KATW 2GYRB 2QR0I 2V5EB 2X1WA 2X1WB 1VPFC 2P6AB 1REWA 1CZ8W 1NYUB 1LX5A 1REWB 1QTYW 2XV7A 2ASKA 1TZHV 1ES7A 2ASKB 2QR0J 3KFDA 1HRPB 3B4VF 1BJ1V 2C7WA 3MJGB 2C7WB 2VWEB 2GYZA 1TFGA 1WAQA 2GH0D 2QJ9A 1RV6V 2QJ9B 2FJGV 1E9JA 2GH0C 1PDGA 1S4YB 2GNND 1AGQC 1PDGC 1DZ7A 1VPPW 2VPFH 1FLTV 2GNNC 1HD4A 2QR0P 1KLAA 1SGFY 1KTZA 1VPFD 2GYRA 1KATV 1TGKA 2QJAA 3KFDD 1HCNA 2QJAB 2P6AA 1HCNB 3BDYV 3EO1L 2BHKA 2H64A 1CZ8V 1ES7C 3KFDC 2GOOD 1QTYV 2VPFA 1ZKZA 2VPFB 3QTKA 1HRPA 3QTKB 2B0UB 3FUBD 3MJGA 1FL7D 2QR0O 2VWEA 1XWDD 3B4VE 1B98A 1FL7C 1M4UL 1AGQD
chains in the KnotProt database with same CATH topology
3EVSB 1VPPV 1XWDE 2GYRD 2VPFG 2X1WD 1BMPA 1NYUD 2GYRC 3BK3B 2QCQA 2X1WC 2QCQB 1VPFB 2FJHW 1QFWB 3HH2A 2GYRF 3HH2B 2QR0D 2R52A 2GYRE 2R52B 3EO1C 2QR0C 1BNDA 1REUA 2ARVA 1BNDB 2VPFF 2ARVB 2B0UA 2QCWB 3QTKF 2QR0U 2XACA 3QTKE 2X1XE 2XACB 1S4YD 1QTYS 3BMPA 2H62A 1SGFB 2H62B 1NYSB 2R53B 1FZVA 1AGQB 1FZVB 2QR0V 2GNNA 1WQ8A 1NT3A 2GNNB 2QJBA 2QJBB 1LXIA 2TGIA 3BK3A 1TZIV 1BTGB 1VPFA 1TZHW 1QFWA 1WQ9A 2VPFD 1WQ9B 3QTKD 2FJHV 3KFDB 3B4VA 3B4VB 1BJ1W 2VPFC 1QTYR 1KLCA 2PJYA 3QTKC 1KLCB 1MJVA 2GOOA 1MJVB 1RV6W 2QCWA 2FJGW 2VPFE 2ARPA 3FUBB 1FL7A 1FL7B 1XWDA 1XWDB 1PDGB 1B8MA 1FLTW 2R53A 1AGQA 1AOCA 1AOCB 1TGJA 1KLAB 3EO1I 1KATW 2GYRB 2QR0I 2V5EB 2X1WA 2X1WB 1VPFC 2P6AB 1REWA 1CZ8W 1NYUB 1LX5A 1REWB 1QTYW 2XV7A 2ASKA 1TZHV 1ES7A 2ASKB 2QR0J 3KFDA 1HRPB 3B4VF 1BJ1V 2C7WA 3MJGB 2C7WB 2VWEB 2GYZA 1TFGA 1WAQA 2GH0D 2QJ9A 1RV6V 2QJ9B 2FJGV 1E9JA 2GH0C 1PDGA 1S4YB 2GNND 1AGQC 1PDGC 1DZ7A 1VPPW 2VPFH 1FLTV 2GNNC 1HD4A 2QR0P 1KLAA 1SGFY 1KTZA 1VPFD 2GYRA 1KATV 1TGKA 2QJAA 3KFDD 1HCNA 2QJAB 2P6AA 1HCNB 3BDYV 3EO1L 2BHKA 2H64A 1CZ8V 1ES7C 3KFDC 2GOOD 1QTYV 2VPFA 1ZKZA 2VPFB 3QTKA 1HRPA 3QTKB 2B0UB 3FUBD 3MJGA 1FL7D 2QR0O 2VWEA 1XWDD 3B4VE 1B98A 1FL7C 1M4UL 1AGQD
chains in the KnotProt database with same CATH homology

  
#chains in the KnotProt database with same CATH superfamily
 3EVS B;  1VPP V;  1XWD E;  2GYR D;  2VPF G;  2X1W D;  1BMP A;  1NYU D;  2GYR C;  3BK3 B;  2QCQ A;  2X1W C;  2QCQ B;  1VPF B;  2FJH W;  1QFW B;  3HH2 A;  2GYR F;  3HH2 B;  2QR0 D;  2R52 A;  2GYR E;  2R52 B;  3EO1 C;  2QR0 C;  1BND A;  1REU A;  2ARV A;  1BND B;  2VPF F;  2ARV B;  2B0U A;  2QCW B;  3QTK F;  2QR0 U;  2XAC A;  3QTK E;  2X1X E;  2XAC B;  1S4Y D;  1QTY S;  3BMP A;  2H62 A;  1SGF B;  2H62 B;  1NYS B;  2R53 B;  1FZV A;  1AGQ B;  1FZV B;  2QR0 V;  2GNN A;  1WQ8 A;  1NT3 A;  2GNN B;  2QJB A;  2QJB B;  1LXI A;  2TGI A;  3BK3 A;  1TZI V;  1BTG B;  1VPF A;  1TZH W;  1QFW A;  1WQ9 A;  2VPF D;  1WQ9 B;  3QTK D;  2FJH V;  3KFD B;  3B4V A;  3B4V B;  1BJ1 W;  2VPF C;  1QTY R;  1KLC A;  2PJY A;  3QTK C;  1KLC B;  1MJV A;  2GOO A;  1MJV B;  1RV6 W;  2QCW A;  2FJG W;  2VPF E;  2ARP A;  3FUB B;  1FL7 A;  1FL7 B;  1XWD A;  1XWD B;  1PDG B;  1B8M A;  1FLT W;  2R53 A;  1AGQ A;  1AOC A;  1AOC B;  1TGJ A;  1KLA B;  3EO1 I;  1KAT W;  2GYR B;  2QR0 I;  2V5E B;  2X1W A;  2X1W B;  1VPF C;  2P6A B;  1REW A;  1CZ8 W;  1NYU B;  1LX5 A;  1REW B;  1QTY W;  2XV7 A;  2ASK A;  1TZH V;  1ES7 A;  2ASK B;  2QR0 J;  3KFD A;  1HRP B;  3B4V F;  1BJ1 V;  2C7W A;  3MJG B;  2C7W B;  2VWE B;  2GYZ A;  1TFG A;  1WAQ A;  2GH0 D;  2QJ9 A;  1RV6 V;  2QJ9 B;  2FJG V;  1E9J A;  2GH0 C;  1PDG A;  1S4Y B;  2GNN D;  1AGQ C;  1PDG C;  1DZ7 A;  1VPP W;  2VPF H;  1FLT V;  2GNN C;  1HD4 A;  2QR0 P;  1KLA A;  1SGF Y;  1KTZ A;  1VPF D;  2GYR A;  1KAT V;  1TGK A;  2QJA A;  3KFD D;  1HCN A;  2QJA B;  2P6A A;  1HCN B;  3BDY V;  3EO1 L;  2BHK A;  2H64 A;  1CZ8 V;  1ES7 C;  3KFD C;  2GOO D;  1QTY V;  2VPF A;  1ZKZ A;  2VPF B;  3QTK A;  1HRP A;  3QTK B;  2B0U B;  3FUB D;  3MJG A;  1FL7 D;  2QR0 O;  2VWE A;  1XWD D;  3B4V E;  1B98 A;  1FL7 C;  1M4U L;  1AGQ D; 
#chains in the KnotProt database with same CATH topology
 3EVS B;  1VPP V;  1XWD E;  2GYR D;  2VPF G;  2X1W D;  1BMP A;  1NYU D;  2GYR C;  3BK3 B;  2QCQ A;  2X1W C;  2QCQ B;  1VPF B;  2FJH W;  1QFW B;  3HH2 A;  2GYR F;  3HH2 B;  2QR0 D;  2R52 A;  2GYR E;  2R52 B;  3EO1 C;  2QR0 C;  1BND A;  1REU A;  2ARV A;  1BND B;  2VPF F;  2ARV B;  2B0U A;  2QCW B;  3QTK F;  2QR0 U;  2XAC A;  3QTK E;  2X1X E;  2XAC B;  1S4Y D;  1QTY S;  3BMP A;  2H62 A;  1SGF B;  2H62 B;  1NYS B;  2R53 B;  1FZV A;  1AGQ B;  1FZV B;  2QR0 V;  2GNN A;  1WQ8 A;  1NT3 A;  2GNN B;  2QJB A;  2QJB B;  1LXI A;  2TGI A;  3BK3 A;  1TZI V;  1BTG B;  1VPF A;  1TZH W;  1QFW A;  1WQ9 A;  2VPF D;  1WQ9 B;  3QTK D;  2FJH V;  3KFD B;  3B4V A;  3B4V B;  1BJ1 W;  2VPF C;  1QTY R;  1KLC A;  2PJY A;  3QTK C;  1KLC B;  1MJV A;  2GOO A;  1MJV B;  1RV6 W;  2QCW A;  2FJG W;  2VPF E;  2ARP A;  3FUB B;  1FL7 A;  1FL7 B;  1XWD A;  1XWD B;  1PDG B;  1B8M A;  1FLT W;  2R53 A;  1AGQ A;  1AOC A;  1AOC B;  1TGJ A;  1KLA B;  3EO1 I;  1KAT W;  2GYR B;  2QR0 I;  2V5E B;  2X1W A;  2X1W B;  1VPF C;  2P6A B;  1REW A;  1CZ8 W;  1NYU B;  1LX5 A;  1REW B;  1QTY W;  2XV7 A;  2ASK A;  1TZH V;  1ES7 A;  2ASK B;  2QR0 J;  3KFD A;  1HRP B;  3B4V F;  1BJ1 V;  2C7W A;  3MJG B;  2C7W B;  2VWE B;  2GYZ A;  1TFG A;  1WAQ A;  2GH0 D;  2QJ9 A;  1RV6 V;  2QJ9 B;  2FJG V;  1E9J A;  2GH0 C;  1PDG A;  1S4Y B;  2GNN D;  1AGQ C;  1PDG C;  1DZ7 A;  1VPP W;  2VPF H;  1FLT V;  2GNN C;  1HD4 A;  2QR0 P;  1KLA A;  1SGF Y;  1KTZ A;  1VPF D;  2GYR A;  1KAT V;  1TGK A;  2QJA A;  3KFD D;  1HCN A;  2QJA B;  2P6A A;  1HCN B;  3BDY V;  3EO1 L;  2BHK A;  2H64 A;  1CZ8 V;  1ES7 C;  3KFD C;  2GOO D;  1QTY V;  2VPF A;  1ZKZ A;  2VPF B;  3QTK A;  1HRP A;  3QTK B;  2B0U B;  3FUB D;  3MJG A;  1FL7 D;  2QR0 O;  2VWE A;  1XWD D;  3B4V E;  1B98 A;  1FL7 C;  1M4U L;  1AGQ D; 
#chains in the KnotProt database with same CATH homology
 3EVS B;  1VPP V;  1XWD E;  2GYR D;  2VPF G;  2X1W D;  1BMP A;  1NYU D;  2GYR C;  3BK3 B;  2QCQ A;  2X1W C;  2QCQ B;  1VPF B;  2FJH W;  1QFW B;  3HH2 A;  2GYR F;  3HH2 B;  2QR0 D;  2R52 A;  2GYR E;  2R52 B;  3EO1 C;  2QR0 C;  1BND A;  1REU A;  2ARV A;  1BND B;  2VPF F;  2ARV B;  2B0U A;  2QCW B;  3QTK F;  2QR0 U;  2XAC A;  3QTK E;  2X1X E;  2XAC B;  1S4Y D;  1QTY S;  3BMP A;  2H62 A;  1SGF B;  2H62 B;  1NYS B;  2R53 B;  1FZV A;  1AGQ B;  1FZV B;  2QR0 V;  2GNN A;  1WQ8 A;  1NT3 A;  2GNN B;  2QJB A;  2QJB B;  1LXI A;  2TGI A;  3BK3 A;  1TZI V;  1BTG B;  1VPF A;  1TZH W;  1QFW A;  1WQ9 A;  2VPF D;  1WQ9 B;  3QTK D;  2FJH V;  3KFD B;  3B4V A;  3B4V B;  1BJ1 W;  2VPF C;  1QTY R;  1KLC A;  2PJY A;  3QTK C;  1KLC B;  1MJV A;  2GOO A;  1MJV B;  1RV6 W;  2QCW A;  2FJG W;  2VPF E;  2ARP A;  3FUB B;  1FL7 A;  1FL7 B;  1XWD A;  1XWD B;  1PDG B;  1B8M A;  1FLT W;  2R53 A;  1AGQ A;  1AOC A;  1AOC B;  1TGJ A;  1KLA B;  3EO1 I;  1KAT W;  2GYR B;  2QR0 I;  2V5E B;  2X1W A;  2X1W B;  1VPF C;  2P6A B;  1REW A;  1CZ8 W;  1NYU B;  1LX5 A;  1REW B;  1QTY W;  2XV7 A;  2ASK A;  1TZH V;  1ES7 A;  2ASK B;  2QR0 J;  3KFD A;  1HRP B;  3B4V F;  1BJ1 V;  2C7W A;  3MJG B;  2C7W B;  2VWE B;  2GYZ A;  1TFG A;  1WAQ A;  2GH0 D;  2QJ9 A;  1RV6 V;  2QJ9 B;  2FJG V;  1E9J A;  2GH0 C;  1PDG A;  1S4Y B;  2GNN D;  1AGQ C;  1PDG C;  1DZ7 A;  1VPP W;  2VPF H;  1FLT V;  2GNN C;  1HD4 A;  2QR0 P;  1KLA A;  1SGF Y;  1KTZ A;  1VPF D;  2GYR A;  1KAT V;  1TGK A;  2QJA A;  3KFD D;  1HCN A;  2QJA B;  2P6A A;  1HCN B;  3BDY V;  3EO1 L;  2BHK A;  2H64 A;  1CZ8 V;  1ES7 C;  3KFD C;  2GOO D;  1QTY V;  2VPF A;  1ZKZ A;  2VPF B;  3QTK A;  1HRP A;  3QTK B;  2B0U B;  3FUB D;  3MJG A;  1FL7 D;  2QR0 O;  2VWE A;  1XWD D;  3B4V E;  1B98 A;  1FL7 C;  1M4U L;  1AGQ D;
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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