1EOLA

Design of p1' and p3' residues of trivalent thrombin inhibitors and their crystal structures
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Genus: 67
Slipknot S +31

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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 30-242 213 1-29 253-289 243-252 29 37 slipknot
Chain Sequence
GGADCGLRPLFEKKSLEDKTERELLESYI---IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKEGQP--------SVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQF
Whole chain analysis

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Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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2.1m 24-228 205 1-23 235-278 229-234 23 44 slipknot
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3.1m 30-232 203 1-29 241-278 233-240 29 38 slipknot
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2.1m 14-240 227 1-13 245-278 241-244 13 34 slipknot
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2.1m 29-240 212 1-13, 244-278 14-28, 241-243 13 35 slipknot
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2.1m 30-240 211 1-28, 243-278 29-29, 241-242 28 36 slipknot
How to cite
KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling