1SL3A

Crystal structue of thrombin in complex with a potent p1 heterocycle-aryl based inhibitor
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Genus: 64
Slipknot S +31

  Help Knotting data interpretation Full screen
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 27-238 212 1-26 250-287 239-249 26 38 slipknot
Chain Sequence
DCGLRPLFEKKSLEDKTERELLESYI---IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKEGQP--------SVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFG
Whole chain analysis

  Help Knotoid data interpretation Full screen
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


  Help Knotoid subchains data interpretation Full screen
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
3.1m 27-229 203 1-26 238-276 230-237 26 39 slipknot
view details
2.1m 27-237 211 1-26 240-276 238-239 26 37 slipknot
view details
2.1m 27-239 213 1-26 241-276 240-240 26 36 slipknot
view details
2.1m 25-226 202 1-5, 230-276 6-24, 227-229 5 47 slipknot
view details
2.1m 26-227 202 1-24, 230-276 25-25, 228-229 24 47 slipknot
How to cite
KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling