1TA2A

Crystal structure of thrombin in complex with compound 1
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 27-238 212 1-26 250-287 239-249 26 38 slipknot
Chain Sequence
DCGLRPLFEKKSLEDKTERELLESYI---IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKEGQP--------SVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFG
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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2.1m 26-226 201 1-25 231-276 227-230 25 46 slipknot
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3.1m 27-229 203 1-26 239-276 230-238 26 38 slipknot
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2.1m 21-238 218 1-20 241-276 239-240 20 36 slipknot
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3.1m 27-238 212 1-21, 240-276 22-26, 239-239 21 37 slipknot
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2.1m 27-239 213 1-21, 241-276 22-26, 240-240 21 36 slipknot
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2.1m 25-240 216 1-9, 242-276 10-24, 241-241 9 35 slipknot

KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling