2A65A

Crystal structure of leutaa, a bacterial homolog of na+/cl--dependent neurotransmitter transporters
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
  • Chain breaks within knot 41 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Slipknot S +31 41 +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 39-264 226 265-511 1-20 21-38 20 246 slipknot
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41 13-293 281 1-12 349-511 294-348 12 163 slipknot
Chain Sequence
REHWATRLGLILAMAGNAVGLGNFLRFPVQAAENGGGAFMIPYIIAFLLVGIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVVAIYYVYIESWTLGFAIKFLVGLVPEPPP--TDPDSILRPFKEFLYSYIGVPKGDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFTLSLGFGAIITYASYVRKDQDIVLSGLTAATLNEKAEVILGGSISIPAAVAFFGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLTSSIAIMQPMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFWAGTIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRYITPAFLAVLLVVWAREYIPKIMEETHWTVWITRFYIIGLFLFLTFLVFLAERRRNHESAGT
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.2 10-288 279 1-9 303-509 289-302 9 207 slipknot
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4.1 10-302 293 1-9 306-509 303-305 9 204 slipknot
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4.1 9-305 297 1-8 309-509 306-308 8 201 slipknot
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3.2 6-315 310 1-5 322-509 316-321 5 188 slipknot
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3.2 13-333 321 1-12 349-509 334-348 12 161 slipknot
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4.1 11-326 316 1-3, 332-509 4-10, 327-331 3 178 slipknot
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2.1 25-263 239 1-15, 273-509 16-24, 264-272 15 237 slipknot
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2.1 30-254 225 1-16, 274-509 17-29, 255-273 16 236 slipknot
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2.1 24-485 462 1-16, 502-509 17-23, 486-501 16 8 slipknot
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2.1 30-413 384 1-17, 448-509 18-29, 414-447 17 62 slipknot
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2.1 40-353 314 1-18, 392-509 19-39, 354-391 18 118 slipknot
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2.1 41-410 370 411-509 1-18 19-40 18 98 slipknot
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2.1 33-262 230 1-29, 267-509 30-32, 263-266 29 243 slipknot
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2.1 41-279 239 1-29, 293-509 30-40, 280-292 29 217 slipknot
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1.1 40-245 206 1-32, 258-509 33-39, 246-257 32 252 slipknot
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2.1 42-260 219 1-35, 272-509 36-41, 261-271 35 238 slipknot
missing residues 129-130
publication title Crystal structure of a bacterial homologue of Na(+)/Cl(-)-dependent neurotransmitter transporters.
pubmed doi rcsb
structure length 509
molecule tags Transport protein
source organism Aquifex aeolicus
sequence length 511
total genus Genus: 217
molecule keywords Na(+):neurotransmitter symporter (Snf family)
ec nomenclature
pdb deposition date 2005-07-01
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00209 SNF Sodium:neurotransmitter symporter family
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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