2GH0C

Growth factor/receptor complex
Cysteine knot
Loop Piercing
view details
150-c-154-b-218-c-216 123-b-188
Chain Sequence
DPGCRLRSQLVPVRALGLGHRSDELVRFRFCSGSCRRARSPHDLSLASLLGAGALRPPPGSRPVSQPCCRPTRYEAVSFMDVNSTWRTVDRLSATACGCL
sequence length 100
structure length 100
publication title Structure of Artemin Complexed with Its Receptor GFRalpha3: Convergent Recognition of Glial Cell Line-Derived Neurotrophic Factors.
pubmed doi rcsb
molecule tags Hormone/growth factor
molecule keywords artemin
source organism Homo sapiens
ec nomenclature
pdb deposition date 2006-03-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.90.10 Mainly Beta Ribbon Cystine Knot Cytokines, subunit B Cystine-knot cytokines 2gh0C00
1QTYV 2ASKB 2GYRC 2GYRF 1VPFD 1CZ8W 3BMPA 1AGQD 1TZHV 2GYRE 1B98A 1QFWA 1KTZA 2ARPA 3QTKB 2R52A 1QTYS 3HH2A 3B4VA 1BTGB 1KATV 1BJ1V 1AOCA 3MJGA 1MJVB 1RV6V 3FUBD 3EVSB 2FJHW 2H62A 1NYUB 1QTYR 2GYZA 2B0UB 2VPFA 2GOOA 2QCWB 1FLTV 2P6AB 2QJ9A 2PJYA 3BK3B 1DZ7A 3KFDB 2QJBA 2ARVB 2X1WC 1XWDB 2GNNB 1NYSB 1TZIV 2X1WD 1S4YB 1VPPV 1FL7A 1WQ9A 1TGJA 1LXIA 1QFWB 2GYRD 3EO1I 1HCNA 2QR0C 1QTYW 1VPFA 2R52B 3HH2B 3B4VB 1AGQA 2QR0J 1PDGC 2GH0C 2QR0O 1E9JA 2GYRA 2QR0D 1LX5A 1KLCA 2QJAA 2FJGV 2XACA 3MJGB 2GH0D 1BNDA 1REUA 1REWA 1BJ1W 1SGFY 2C7WA 2H62B 3QTKF 3QTKC 2VPFB 3FUBB 1RV6W 2QJ9B 2QR0P 1FZVA 2QJBB 3BDYV 3QTKE 1ES7C 2H64A 1FL7B 1WQ9B 2VPFH 1KLAA 2R53A 2QR0I 1HCNB 1WAQA 2X1WA 1VPFB 2QR0V 1VPPW 3KFDC 2VPFE 1AGQB 1NYUD 2GNNC 1TZHW 2GYRB 1KLCB 1AOCB 2QCQA 1HRPA 1XWDE 2QJAB 2V5EB 2XACB 3KFDD 3EO1L 1XWDD 1BNDB 2VWEA 1REWB 3BK3A 1KATW 1CZ8V 2C7WB 1ZKZA 1TGKA 1M4UL 1PDGA 3B4VF 1FZVB 2ASKA 1TFGA 2X1XE 3QTKD 3B4VE 1FLTW 3EO1C 3QTKA 1KLAB 2R53B 2VPFF 2VPFC 1HD4A 2X1WB 2FJHV 1BMPA 1ES7A 2QR0U 1MJVA 2BHKA 2GOOD 1B8MA 2VPFD 2VPFG 2QCQB 1HRPB 1FL7C 2VWEB 2GNND 2B0UA 2QCWA 2P6AA 1SGFB 1S4YD 1FL7D 3KFDA 1VPFC 2ARVA 1XWDA 1PDGB 2FJGW 2GNNA 1NT3A 2TGIA 1AGQC 2XV7A 1WQ8A
chains in the KnotProt database with same CATH superfamily
1QTYV 2ASKB 2GYRC 2GYRF 1VPFD 1CZ8W 3BMPA 1AGQD 1TZHV 2GYRE 1B98A 1QFWA 1KTZA 2ARPA 3QTKB 2R52A 1QTYS 3HH2A 3B4VA 1BTGB 1KATV 1BJ1V 1AOCA 3MJGA 1MJVB 1RV6V 3FUBD 3EVSB 2FJHW 2H62A 1NYUB 1QTYR 2GYZA 2B0UB 2VPFA 2GOOA 2QCWB 1FLTV 2P6AB 2QJ9A 2PJYA 3BK3B 1DZ7A 3KFDB 2QJBA 2ARVB 2X1WC 1XWDB 2GNNB 1NYSB 1TZIV 2X1WD 1S4YB 1VPPV 1FL7A 1WQ9A 1TGJA 1LXIA 1QFWB 2GYRD 3EO1I 1HCNA 2QR0C 1QTYW 1VPFA 2R52B 3HH2B 3B4VB 1AGQA 2QR0J 1PDGC 2GH0C 2QR0O 1E9JA 2GYRA 2QR0D 1LX5A 1KLCA 2QJAA 2FJGV 2XACA 3MJGB 2GH0D 1BNDA 1REUA 1REWA 1BJ1W 1SGFY 2C7WA 2H62B 3QTKF 3QTKC 2VPFB 3FUBB 1RV6W 2QJ9B 2QR0P 1FZVA 2QJBB 3BDYV 3QTKE 1ES7C 2H64A 1FL7B 1WQ9B 2VPFH 1KLAA 2R53A 2QR0I 1HCNB 1WAQA 2X1WA 1VPFB 2QR0V 1VPPW 3KFDC 2VPFE 1AGQB 1NYUD 2GNNC 1TZHW 2GYRB 1KLCB 1AOCB 2QCQA 1HRPA 1XWDE 2QJAB 2V5EB 2XACB 3KFDD 3EO1L 1XWDD 1BNDB 2VWEA 1REWB 3BK3A 1KATW 1CZ8V 2C7WB 1ZKZA 1TGKA 1M4UL 1PDGA 3B4VF 1FZVB 2ASKA 1TFGA 2X1XE 3QTKD 3B4VE 1FLTW 3EO1C 3QTKA 1KLAB 2R53B 2VPFF 2VPFC 1HD4A 2X1WB 2FJHV 1BMPA 1ES7A 2QR0U 1MJVA 2BHKA 2GOOD 1B8MA 2VPFD 2VPFG 2QCQB 1HRPB 1FL7C 2VWEB 2GNND 2B0UA 2QCWA 2P6AA 1SGFB 1S4YD 1FL7D 3KFDA 1VPFC 2ARVA 1XWDA 1PDGB 2FJGW 2GNNA 1NT3A 2TGIA 1AGQC 2XV7A 1WQ8A
chains in the KnotProt database with same CATH topology
1QTYV 2ASKB 2GYRC 2GYRF 1VPFD 1CZ8W 3BMPA 1AGQD 1TZHV 2GYRE 1B98A 1QFWA 1KTZA 2ARPA 3QTKB 2R52A 1QTYS 3HH2A 3B4VA 1BTGB 1KATV 1BJ1V 1AOCA 3MJGA 1MJVB 1RV6V 3FUBD 3EVSB 2FJHW 2H62A 1NYUB 1QTYR 2GYZA 2B0UB 2VPFA 2GOOA 2QCWB 1FLTV 2P6AB 2QJ9A 2PJYA 3BK3B 1DZ7A 3KFDB 2QJBA 2ARVB 2X1WC 1XWDB 2GNNB 1NYSB 1TZIV 2X1WD 1S4YB 1VPPV 1FL7A 1WQ9A 1TGJA 1LXIA 1QFWB 2GYRD 3EO1I 1HCNA 2QR0C 1QTYW 1VPFA 2R52B 3HH2B 3B4VB 1AGQA 2QR0J 1PDGC 2GH0C 2QR0O 1E9JA 2GYRA 2QR0D 1LX5A 1KLCA 2QJAA 2FJGV 2XACA 3MJGB 2GH0D 1BNDA 1REUA 1REWA 1BJ1W 1SGFY 2C7WA 2H62B 3QTKF 3QTKC 2VPFB 3FUBB 1RV6W 2QJ9B 2QR0P 1FZVA 2QJBB 3BDYV 3QTKE 1ES7C 2H64A 1FL7B 1WQ9B 2VPFH 1KLAA 2R53A 2QR0I 1HCNB 1WAQA 2X1WA 1VPFB 2QR0V 1VPPW 3KFDC 2VPFE 1AGQB 1NYUD 2GNNC 1TZHW 2GYRB 1KLCB 1AOCB 2QCQA 1HRPA 1XWDE 2QJAB 2V5EB 2XACB 3KFDD 3EO1L 1XWDD 1BNDB 2VWEA 1REWB 3BK3A 1KATW 1CZ8V 2C7WB 1ZKZA 1TGKA 1M4UL 1PDGA 3B4VF 1FZVB 2ASKA 1TFGA 2X1XE 3QTKD 3B4VE 1FLTW 3EO1C 3QTKA 1KLAB 2R53B 2VPFF 2VPFC 1HD4A 2X1WB 2FJHV 1BMPA 1ES7A 2QR0U 1MJVA 2BHKA 2GOOD 1B8MA 2VPFD 2VPFG 2QCQB 1HRPB 1FL7C 2VWEB 2GNND 2B0UA 2QCWA 2P6AA 1SGFB 1S4YD 1FL7D 3KFDA 1VPFC 2ARVA 1XWDA 1PDGB 2FJGW 2GNNA 1NT3A 2TGIA 1AGQC 2XV7A 1WQ8A
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 1QTY V;  2ASK B;  2GYR C;  2GYR F;  1VPF D;  1CZ8 W;  3BMP A;  1AGQ D;  1TZH V;  2GYR E;  1B98 A;  1QFW A;  1KTZ A;  2ARP A;  3QTK B;  2R52 A;  1QTY S;  3HH2 A;  3B4V A;  1BTG B;  1KAT V;  1BJ1 V;  1AOC A;  3MJG A;  1MJV B;  1RV6 V;  3FUB D;  3EVS B;  2FJH W;  2H62 A;  1NYU B;  1QTY R;  2GYZ A;  2B0U B;  2VPF A;  2GOO A;  2QCW B;  1FLT V;  2P6A B;  2QJ9 A;  2PJY A;  3BK3 B;  1DZ7 A;  3KFD B;  2QJB A;  2ARV B;  2X1W C;  1XWD B;  2GNN B;  1NYS B;  1TZI V;  2X1W D;  1S4Y B;  1VPP V;  1FL7 A;  1WQ9 A;  1TGJ A;  1LXI A;  1QFW B;  2GYR D;  3EO1 I;  1HCN A;  2QR0 C;  1QTY W;  1VPF A;  2R52 B;  3HH2 B;  3B4V B;  1AGQ A;  2QR0 J;  1PDG C;  2GH0 C;  2QR0 O;  1E9J A;  2GYR A;  2QR0 D;  1LX5 A;  1KLC A;  2QJA A;  2FJG V;  2XAC A;  3MJG B;  2GH0 D;  1BND A;  1REU A;  1REW A;  1BJ1 W;  1SGF Y;  2C7W A;  2H62 B;  3QTK F;  3QTK C;  2VPF B;  3FUB B;  1RV6 W;  2QJ9 B;  2QR0 P;  1FZV A;  2QJB B;  3BDY V;  3QTK E;  1ES7 C;  2H64 A;  1FL7 B;  1WQ9 B;  2VPF H;  1KLA A;  2R53 A;  2QR0 I;  1HCN B;  1WAQ A;  2X1W A;  1VPF B;  2QR0 V;  1VPP W;  3KFD C;  2VPF E;  1AGQ B;  1NYU D;  2GNN C;  1TZH W;  2GYR B;  1KLC B;  1AOC B;  2QCQ A;  1HRP A;  1XWD E;  2QJA B;  2V5E B;  2XAC B;  3KFD D;  3EO1 L;  1XWD D;  1BND B;  2VWE A;  1REW B;  3BK3 A;  1KAT W;  1CZ8 V;  2C7W B;  1ZKZ A;  1TGK A;  1M4U L;  1PDG A;  3B4V F;  1FZV B;  2ASK A;  1TFG A;  2X1X E;  3QTK D;  3B4V E;  1FLT W;  3EO1 C;  3QTK A;  1KLA B;  2R53 B;  2VPF F;  2VPF C;  1HD4 A;  2X1W B;  2FJH V;  1BMP A;  1ES7 A;  2QR0 U;  1MJV A;  2BHK A;  2GOO D;  1B8M A;  2VPF D;  2VPF G;  2QCQ B;  1HRP B;  1FL7 C;  2VWE B;  2GNN D;  2B0U A;  2QCW A;  2P6A A;  1SGF B;  1S4Y D;  1FL7 D;  3KFD A;  1VPF C;  2ARV A;  1XWD A;  1PDG B;  2FJG W;  2GNN A;  1NT3 A;  2TGI A;  1AGQ C;  2XV7 A;  1WQ8 A; 
#chains in the KnotProt database with same CATH topology
 1QTY V;  2ASK B;  2GYR C;  2GYR F;  1VPF D;  1CZ8 W;  3BMP A;  1AGQ D;  1TZH V;  2GYR E;  1B98 A;  1QFW A;  1KTZ A;  2ARP A;  3QTK B;  2R52 A;  1QTY S;  3HH2 A;  3B4V A;  1BTG B;  1KAT V;  1BJ1 V;  1AOC A;  3MJG A;  1MJV B;  1RV6 V;  3FUB D;  3EVS B;  2FJH W;  2H62 A;  1NYU B;  1QTY R;  2GYZ A;  2B0U B;  2VPF A;  2GOO A;  2QCW B;  1FLT V;  2P6A B;  2QJ9 A;  2PJY A;  3BK3 B;  1DZ7 A;  3KFD B;  2QJB A;  2ARV B;  2X1W C;  1XWD B;  2GNN B;  1NYS B;  1TZI V;  2X1W D;  1S4Y B;  1VPP V;  1FL7 A;  1WQ9 A;  1TGJ A;  1LXI A;  1QFW B;  2GYR D;  3EO1 I;  1HCN A;  2QR0 C;  1QTY W;  1VPF A;  2R52 B;  3HH2 B;  3B4V B;  1AGQ A;  2QR0 J;  1PDG C;  2GH0 C;  2QR0 O;  1E9J A;  2GYR A;  2QR0 D;  1LX5 A;  1KLC A;  2QJA A;  2FJG V;  2XAC A;  3MJG B;  2GH0 D;  1BND A;  1REU A;  1REW A;  1BJ1 W;  1SGF Y;  2C7W A;  2H62 B;  3QTK F;  3QTK C;  2VPF B;  3FUB B;  1RV6 W;  2QJ9 B;  2QR0 P;  1FZV A;  2QJB B;  3BDY V;  3QTK E;  1ES7 C;  2H64 A;  1FL7 B;  1WQ9 B;  2VPF H;  1KLA A;  2R53 A;  2QR0 I;  1HCN B;  1WAQ A;  2X1W A;  1VPF B;  2QR0 V;  1VPP W;  3KFD C;  2VPF E;  1AGQ B;  1NYU D;  2GNN C;  1TZH W;  2GYR B;  1KLC B;  1AOC B;  2QCQ A;  1HRP A;  1XWD E;  2QJA B;  2V5E B;  2XAC B;  3KFD D;  3EO1 L;  1XWD D;  1BND B;  2VWE A;  1REW B;  3BK3 A;  1KAT W;  1CZ8 V;  2C7W B;  1ZKZ A;  1TGK A;  1M4U L;  1PDG A;  3B4V F;  1FZV B;  2ASK A;  1TFG A;  2X1X E;  3QTK D;  3B4V E;  1FLT W;  3EO1 C;  3QTK A;  1KLA B;  2R53 B;  2VPF F;  2VPF C;  1HD4 A;  2X1W B;  2FJH V;  1BMP A;  1ES7 A;  2QR0 U;  1MJV A;  2BHK A;  2GOO D;  1B8M A;  2VPF D;  2VPF G;  2QCQ B;  1HRP B;  1FL7 C;  2VWE B;  2GNN D;  2B0U A;  2QCW A;  2P6A A;  1SGF B;  1S4Y D;  1FL7 D;  3KFD A;  1VPF C;  2ARV A;  1XWD A;  1PDG B;  2FJG W;  2GNN A;  1NT3 A;  2TGI A;  1AGQ C;  2XV7 A;  1WQ8 A; 
#chains in the KnotProt database with same CATH homology
 1QTY V;  2ASK B;  2GYR C;  2GYR F;  1VPF D;  1CZ8 W;  3BMP A;  1AGQ D;  1TZH V;  2GYR E;  1B98 A;  1QFW A;  1KTZ A;  2ARP A;  3QTK B;  2R52 A;  1QTY S;  3HH2 A;  3B4V A;  1BTG B;  1KAT V;  1BJ1 V;  1AOC A;  3MJG A;  1MJV B;  1RV6 V;  3FUB D;  3EVS B;  2FJH W;  2H62 A;  1NYU B;  1QTY R;  2GYZ A;  2B0U B;  2VPF A;  2GOO A;  2QCW B;  1FLT V;  2P6A B;  2QJ9 A;  2PJY A;  3BK3 B;  1DZ7 A;  3KFD B;  2QJB A;  2ARV B;  2X1W C;  1XWD B;  2GNN B;  1NYS B;  1TZI V;  2X1W D;  1S4Y B;  1VPP V;  1FL7 A;  1WQ9 A;  1TGJ A;  1LXI A;  1QFW B;  2GYR D;  3EO1 I;  1HCN A;  2QR0 C;  1QTY W;  1VPF A;  2R52 B;  3HH2 B;  3B4V B;  1AGQ A;  2QR0 J;  1PDG C;  2GH0 C;  2QR0 O;  1E9J A;  2GYR A;  2QR0 D;  1LX5 A;  1KLC A;  2QJA A;  2FJG V;  2XAC A;  3MJG B;  2GH0 D;  1BND A;  1REU A;  1REW A;  1BJ1 W;  1SGF Y;  2C7W A;  2H62 B;  3QTK F;  3QTK C;  2VPF B;  3FUB B;  1RV6 W;  2QJ9 B;  2QR0 P;  1FZV A;  2QJB B;  3BDY V;  3QTK E;  1ES7 C;  2H64 A;  1FL7 B;  1WQ9 B;  2VPF H;  1KLA A;  2R53 A;  2QR0 I;  1HCN B;  1WAQ A;  2X1W A;  1VPF B;  2QR0 V;  1VPP W;  3KFD C;  2VPF E;  1AGQ B;  1NYU D;  2GNN C;  1TZH W;  2GYR B;  1KLC B;  1AOC B;  2QCQ A;  1HRP A;  1XWD E;  2QJA B;  2V5E B;  2XAC B;  3KFD D;  3EO1 L;  1XWD D;  1BND B;  2VWE A;  1REW B;  3BK3 A;  1KAT W;  1CZ8 V;  2C7W B;  1ZKZ A;  1TGK A;  1M4U L;  1PDG A;  3B4V F;  1FZV B;  2ASK A;  1TFG A;  2X1X E;  3QTK D;  3B4V E;  1FLT W;  3EO1 C;  3QTK A;  1KLA B;  2R53 B;  2VPF F;  2VPF C;  1HD4 A;  2X1W B;  2FJH V;  1BMP A;  1ES7 A;  2QR0 U;  1MJV A;  2BHK A;  2GOO D;  1B8M A;  2VPF D;  2VPF G;  2QCQ B;  1HRP B;  1FL7 C;  2VWE B;  2GNN D;  2B0U A;  2QCW A;  2P6A A;  1SGF B;  1S4Y D;  1FL7 D;  3KFD A;  1VPF C;  2ARV A;  1XWD A;  1PDG B;  2FJG W;  2GNN A;  1NT3 A;  2TGI A;  1AGQ C;  2XV7 A;  1WQ8 A; 
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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