| Loop | Piercing | ||||
|---|---|---|---|---|---|
| view details | 43-c-47-b-113-c-111 | 14-b-79 |
Chain Sequence |
SSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR
|
| sequence length |
103
|
| structure length |
103
|
| publication title |
A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor.
pubmed doi rcsb |
| molecule tags |
Hormone/growth factor
|
| molecule keywords |
Bone morphogenetic protein 2
|
| source organism |
Homo sapiens
|
| ec nomenclature | |
| pdb deposition date | 2006-05-30 |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Beta | Ribbon | Cystine Knot Cytokines, subunit B | Cystine-knot cytokines |
#chains in the KnotProt database with same CATH superfamily 2GYR B; 1HCN A; 2QCW A; 2GYR F; 3KFD D; 3FUB D; 2QCW B; 2X1W D; 1FL7 C; 1XWD E; 2PJY A; 2QJB B; 1FZV A; 1BJ1 W; 1PDG C; 1KAT V; 1SGF B; 1LXI A; 2QCQ A; 2ARV B; 3B4V E; 2ASK A; 2QCQ B; 1AGQ A; 2H62 A; 2XV7 A; 2ASK B; 2QR0 O; 1KLC A; 1AGQ B; 2FJG V; 1KLC B; 1AGQ D; 2VPF A; 2VWE A; 3EVS B; 2B0U B; 1QFW B; 2VPF B; 2VWE B; 1AOC A; 3EO1 L; 2VPF F; 2FJH V; 3HH2 A; 3BDY V; 1HD4 A; 1E9J A; 2V5E B; 2VPF D; 3QTK A; 1VPP W; 2QR0 C; 1VPF B; 2GYR A; 3QTK B; 2QR0 I; 2GNN C; 1RV6 W; 1TZH W; 3QTK F; 1CZ8 V; 1TZI V; 3QTK D; 1NYU B; 2QJB A; 2GYR D; 1TFG A; 1FL7 B; 1KAT W; 2ARV A; 1PDG B; 2GH0 D; 1BMP A; 1REW A; 1WQ9 B; 1REW B; 2QR0 J; 1BTG B; 3BK3 B; 2B0U A; 1QFW A; 2P6A B; 1B98 A; 3KFD C; 2BHK A; 1ES7 A; 2X1W C; 2VPF H; 2FJH W; 2GOO A; 2QR0 P; 1VPF A; 1FLT W; 3EO1 C; 1XWD A; 3EO1 I; 2GYR E; 1CZ8 W; 1XWD B; 2ARP A; 2X1X E; 2GOO D; 1BJ1 V; 1VPF D; 2GNN B; 2XAC B; 1LX5 A; 1XWD D; 3B4V A; 2R52 B; 1FL7 A; 1QTY V; 1NYU D; 1AGQ C; 1HRP A; 3B4V B; 3BMP A; 1PDG A; 3B4V F; 2C7W B; 1HRP B; 1KLA B; 1WQ9 A; 1TGJ A; 2TGI A; 1FL7 D; 2R53 B; 2VPF C; 3BK3 A; 2P6A A; 1REU A; 2FJG W; 3MJG B; 2QJA A; 1NT3 A; 2H64 A; 1VPF C; 3QTK C; 1VPP V; 2QJA B; 2VPF E; 1MJV B; 2GYR C; 1S4Y B; 3KFD B; 3FUB B; 1RV6 V; 2QR0 U; 2QR0 V; 2X1W B; 2QJ9 B; 1S4Y D; 3QTK E; 1TGK A; 1HCN B; 2GH0 C; 1SGF Y; 2GNN A; 2VPF G; 2XAC A; 1QTY R; 2R52 A; 1DZ7 A; 1FZV B; 2QR0 D; 2GYZ A; 1QTY W; 1M4U L; 2GNN D; 1WQ8 A; 1BND A; 2C7W A; 1KLA A; 1WAQ A; 1ZKZ A; 1BND B; 2R53 A; 2H62 B; 1KTZ A; 3MJG A; 1ES7 C; 1B8M A; 1NYS B; 1QTY S; 1MJV A; 1AOC B; 1FLT V; 3KFD A; 3HH2 B; 2X1W A; 2QJ9 A; 1TZH V; #chains in the KnotProt database with same CATH topology 2GYR B; 1HCN A; 2QCW A; 2GYR F; 3KFD D; 3FUB D; 2QCW B; 2X1W D; 1FL7 C; 1XWD E; 2PJY A; 2QJB B; 1FZV A; 1BJ1 W; 1PDG C; 1KAT V; 1SGF B; 1LXI A; 2QCQ A; 2ARV B; 3B4V E; 2ASK A; 2QCQ B; 1AGQ A; 2H62 A; 2XV7 A; 2ASK B; 2QR0 O; 1KLC A; 1AGQ B; 2FJG V; 1KLC B; 1AGQ D; 2VPF A; 2VWE A; 3EVS B; 2B0U B; 1QFW B; 2VPF B; 2VWE B; 1AOC A; 3EO1 L; 2VPF F; 2FJH V; 3HH2 A; 3BDY V; 1HD4 A; 1E9J A; 2V5E B; 2VPF D; 3QTK A; 1VPP W; 2QR0 C; 1VPF B; 2GYR A; 3QTK B; 2QR0 I; 2GNN C; 1RV6 W; 1TZH W; 3QTK F; 1CZ8 V; 1TZI V; 3QTK D; 1NYU B; 2QJB A; 2GYR D; 1TFG A; 1FL7 B; 1KAT W; 2ARV A; 1PDG B; 2GH0 D; 1BMP A; 1REW A; 1WQ9 B; 1REW B; 2QR0 J; 1BTG B; 3BK3 B; 2B0U A; 1QFW A; 2P6A B; 1B98 A; 3KFD C; 2BHK A; 1ES7 A; 2X1W C; 2VPF H; 2FJH W; 2GOO A; 2QR0 P; 1VPF A; 1FLT W; 3EO1 C; 1XWD A; 3EO1 I; 2GYR E; 1CZ8 W; 1XWD B; 2ARP A; 2X1X E; 2GOO D; 1BJ1 V; 1VPF D; 2GNN B; 2XAC B; 1LX5 A; 1XWD D; 3B4V A; 2R52 B; 1FL7 A; 1QTY V; 1NYU D; 1AGQ C; 1HRP A; 3B4V B; 3BMP A; 1PDG A; 3B4V F; 2C7W B; 1HRP B; 1KLA B; 1WQ9 A; 1TGJ A; 2TGI A; 1FL7 D; 2R53 B; 2VPF C; 3BK3 A; 2P6A A; 1REU A; 2FJG W; 3MJG B; 2QJA A; 1NT3 A; 2H64 A; 1VPF C; 3QTK C; 1VPP V; 2QJA B; 2VPF E; 1MJV B; 2GYR C; 1S4Y B; 3KFD B; 3FUB B; 1RV6 V; 2QR0 U; 2QR0 V; 2X1W B; 2QJ9 B; 1S4Y D; 3QTK E; 1TGK A; 1HCN B; 2GH0 C; 1SGF Y; 2GNN A; 2VPF G; 2XAC A; 1QTY R; 2R52 A; 1DZ7 A; 1FZV B; 2QR0 D; 2GYZ A; 1QTY W; 1M4U L; 2GNN D; 1WQ8 A; 1BND A; 2C7W A; 1KLA A; 1WAQ A; 1ZKZ A; 1BND B; 2R53 A; 2H62 B; 1KTZ A; 3MJG A; 1ES7 C; 1B8M A; 1NYS B; 1QTY S; 1MJV A; 1AOC B; 1FLT V; 3KFD A; 3HH2 B; 2X1W A; 2QJ9 A; 1TZH V; #chains in the KnotProt database with same CATH homology 2GYR B; 1HCN A; 2QCW A; 2GYR F; 3KFD D; 3FUB D; 2QCW B; 2X1W D; 1FL7 C; 1XWD E; 2PJY A; 2QJB B; 1FZV A; 1BJ1 W; 1PDG C; 1KAT V; 1SGF B; 1LXI A; 2QCQ A; 2ARV B; 3B4V E; 2ASK A; 2QCQ B; 1AGQ A; 2H62 A; 2XV7 A; 2ASK B; 2QR0 O; 1KLC A; 1AGQ B; 2FJG V; 1KLC B; 1AGQ D; 2VPF A; 2VWE A; 3EVS B; 2B0U B; 1QFW B; 2VPF B; 2VWE B; 1AOC A; 3EO1 L; 2VPF F; 2FJH V; 3HH2 A; 3BDY V; 1HD4 A; 1E9J A; 2V5E B; 2VPF D; 3QTK A; 1VPP W; 2QR0 C; 1VPF B; 2GYR A; 3QTK B; 2QR0 I; 2GNN C; 1RV6 W; 1TZH W; 3QTK F; 1CZ8 V; 1TZI V; 3QTK D; 1NYU B; 2QJB A; 2GYR D; 1TFG A; 1FL7 B; 1KAT W; 2ARV A; 1PDG B; 2GH0 D; 1BMP A; 1REW A; 1WQ9 B; 1REW B; 2QR0 J; 1BTG B; 3BK3 B; 2B0U A; 1QFW A; 2P6A B; 1B98 A; 3KFD C; 2BHK A; 1ES7 A; 2X1W C; 2VPF H; 2FJH W; 2GOO A; 2QR0 P; 1VPF A; 1FLT W; 3EO1 C; 1XWD A; 3EO1 I; 2GYR E; 1CZ8 W; 1XWD B; 2ARP A; 2X1X E; 2GOO D; 1BJ1 V; 1VPF D; 2GNN B; 2XAC B; 1LX5 A; 1XWD D; 3B4V A; 2R52 B; 1FL7 A; 1QTY V; 1NYU D; 1AGQ C; 1HRP A; 3B4V B; 3BMP A; 1PDG A; 3B4V F; 2C7W B; 1HRP B; 1KLA B; 1WQ9 A; 1TGJ A; 2TGI A; 1FL7 D; 2R53 B; 2VPF C; 3BK3 A; 2P6A A; 1REU A; 2FJG W; 3MJG B; 2QJA A; 1NT3 A; 2H64 A; 1VPF C; 3QTK C; 1VPP V; 2QJA B; 2VPF E; 1MJV B; 2GYR C; 1S4Y B; 3KFD B; 3FUB B; 1RV6 V; 2QR0 U; 2QR0 V; 2X1W B; 2QJ9 B; 1S4Y D; 3QTK E; 1TGK A; 1HCN B; 2GH0 C; 1SGF Y; 2GNN A; 2VPF G; 2XAC A; 1QTY R; 2R52 A; 1DZ7 A; 1FZV B; 2QR0 D; 2GYZ A; 1QTY W; 1M4U L; 2GNN D; 1WQ8 A; 1BND A; 2C7W A; 1KLA A; 1WAQ A; 1ZKZ A; 1BND B; 2R53 A; 2H62 B; 1KTZ A; 3MJG A; 1ES7 C; 1B8M A; 1NYS B; 1QTY S; 1MJV A; 1AOC B; 1FLT V; 3KFD A; 3HH2 B; 2X1W A; 2QJ9 A; 1TZH V;
#similar chains in the KnotProt database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
