2JLOA

Structure of mhp1, a nucleobase-cation-symport-1 family transporter, in a closed conformation with benzylhydantoin
Slipknot S +31 41 +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 47-223 177 224-461 1-31 32-46 31 237 slipknot
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41 27-261 235 1-26 307-461 262-306 26 155 slipknot
Chain Sequence
RSLLNPSNAPTRYAERSVGPFSLAAIWFAMAIQVAIFIAAGQMTSSFQVWQVIVAIAAGCTIAVILLFFTQSAAIRWGINFTVAARMPFGIRGSLIPITLKALLSLFWFGFQTWLGALALDEITRLLTGFTNLPLWIVIFGAIQVVTTFYGITFIRWMNVFASPVLLAMGVYMVYLMLDGADVSLGEVMSMGGENPGMPFSTAIMIFVGGWIAVVVSIHDIVKECKVDPNASREGQTKADARYATAQWLGMVPASIIFGFIGAASMVLVGEWNPVIAITEVVGGVSIPMAILFQVFVLLATWSTNPAANLLSPAYTLCSTFPRVFTFKTGVIVSAVVGLLMMPWQFAGVLNTFLNLLASALGPLAGIMISDYFLVRRRRISLHDLYRTKGIYTYWRGVNWVALAVYAVALAVSFLTPDLMFVTGLIAALLLHIPAMRWVAKTFPLFSEAESRNEDYLRPIG
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.2 20-256 237 1-19 269-461 257-268 19 193 slipknot
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4.1 22-274 253 1-21 298-461 275-297 21 164 slipknot
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4.1 20-297 278 1-19 301-461 298-300 19 161 slipknot
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3.2 20-300 281 1-19 306-461 301-305 19 156 slipknot
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3.2 18-305 288 1-1, 308-461 2-17, 306-307 1 154 slipknot
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3.2 25-290 266 1-19, 303-461 20-24, 291-302 19 159 slipknot
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3.2 24-302 279 1-19, 306-461 20-23, 303-305 19 156 slipknot
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3.2 25-305 281 1-20, 308-461 21-24, 306-307 20 154 slipknot
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3.2 18-269 252 1-7, 275-461 8-17, 270-274 7 187 slipknot
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4.1 23-266 244 1-14, 271-461 15-22, 267-270 14 191 slipknot
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3.2 26-290 265 1-24, 303-461 25-25, 291-302 24 159 slipknot
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3.2 31-273 243 1-21, 290-461 22-30, 274-289 21 172 slipknot
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3.1 50-217 168 1-28, 246-461 29-49, 218-245 28 216 slipknot
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2.1 57-354 298 355-461 1-28 29-56 28 106 slipknot
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2.1 53-309 257 1-29, 352-461 30-52, 310-351 29 110 slipknot
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1.1 48-247 200 1-34, 266-461 35-47, 248-265 34 196 slipknot
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2.1 50-247 198 1-47, 265-461 48-49, 248-264 47 197 slipknot
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1.1 57-248 192 1-49, 263-461 50-56, 249-262 49 199 slipknot
publication title Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter.
pubmed doi rcsb
structure length 461
molecule tags Membrane protein
source organism Microbacterium liquefaciens
sequence length 461
molecule keywords MHP1
ec nomenclature
pdb deposition date 2008-09-12
KnotProt deposition date 2014-07-31
Image from the rcsb pdb (www.rcsb.org)
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