2M86A

Solution structure of hdm2 with engineered cyclotide
Cysteine knot
Loop Piercing
view details
25-c-32-b-44-c-42 38-b-50
Chain Sequence
SGSGASKAPTSFAEYWNLLSAGGVCPKILQRCRRDSDCPGACICRGNGYCG
sequence length 51
structure length 51
publication title In Vivo Activation of the p53 Tumor Suppressor Pathway by an Engineered Cyclotide.
pubmed doi rcsb
molecule tags Protein binding/signaling protein
molecule keywords MCo-PMI
source organism Synthetic construct
ec nomenclature
pdb deposition date 2013-05-07
Image from the rcsb pdb (www.rcsb.org)
1HA9A 1IB9A 2IT8A 2LJSA 4GUXD 5WOVA 5WOWA 2PO8A
similar chains in the KnotProt database (40% sequence similarity)
8VADA
similar chains in the pdb database (40% sequence similarity)

 
#similar chains in the KnotProt database (40% sequence similarity)
1HA9 A; 1IB9 A; 2IT8 A; 2LJS A; 4GUX D; 5WOV A; 5WOW A; 
#similar chains, but unknotted
2PO8 A; 
#similar chains in the pdb database (40% sequence similarity)
8VAD A; 

KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling
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