2UW9A

Structure of pkb-beta (akt2) complexed with 4-(4-chloro-phenyl)-4-(4-(1h-pyrazol-4-yl)-phenyl)-piperidine
Warning
  • Chain breaks within knot 41 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Genus: 93
Knot K 41 41

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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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41 34-324 291 1-33, 325-337 33 13 knot
Chain Sequence
KVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSIT--------------------QEMFEDFDYIADW
Whole chain analysis

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Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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4.1 12-304 293 1-11, 305-317 11 13 knot
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3.2 15-305 291 306-317 1-11 12-14 11 11 slipknot
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4.1 34-310 277 311-317 1-23 24-33 23 6 slipknot
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3.2 38-304 267 305-317 1-31 32-37 31 12 slipknot
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3.2 39-307 269 308-317 1-37 38-38 37 9 slipknot
How to cite
KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling