2W5WA

Structure of tab5 alkaline phosphatase mutant his 135 asp with zn bound in the m3 site.
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 11-273 263 1-10 314-346 274-313 10 33 slipknot
Chain Sequence
QLKTPKNVILLISDGAGLSQISSTFYFKSGTPNYTQFKNIGLIKTSSSREDVTDSASGATAFSCGIKTYNAAIGVADDSTAVKSIVEIAALNNIKTGVVATSSITDATPASFYAHALNRGLEEEIAMDMTESDLDFFAGGGLNYFTKRKDKKDVLAILKGNQFTINTTALTDFSSIASNRKMGFLLADEAMPTMEKGRGNFLSAATDLAIQFLSKDNSAFFIMSEGSQIDWGGHANNASYLISEINDFDDAIGTALAFAKKDGNTLVIVTSDHETGGFTLAAKKNKREDGSEYSDYTEIGPTFSTGGHSATLIPVFAYGPGSEEFIGIYENNEIFHKILKVTKWNQ
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.1 11-273 263 1-10 309-346 274-308 10 38 slipknot
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2.1 8-309 302 1-7 316-346 310-315 7 31 slipknot
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3.1 8-308 301 1-3, 310-346 4-7, 309-309 3 37 slipknot
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3.1 9-309 301 1-7, 313-346 8-8, 310-312 7 34 slipknot
sequence length 346
structure length 346
publication title Coordination Sphere of the Third Metal Site is Essential to the Activity and Metal Selectivity of Alkaline Phosphatases.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords ALKALINE PHOSPHATASE
source organism Antarctic bacterium tab5
total genus Genus: 130
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2008-12-15
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the pdb database (?% sequence similarity)

 
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