2WDTA

Crystal structure of plasmodium falciparum uchl3 in complex with the suicide inhibitor ubvme
Warning
  • Chain breaks within knot 52 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Genus: 58
Alphaknot: Q8IKM8
Knot K -52 -31 -31

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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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-52 3-220 218 1-2, 221-222 2 2 knot
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-31 6-162 157 1-5 218-222 163-217 5 5 slipknot
Chain Sequence
DIWTPLESNPDSLYLYSCKLGQSKLKFVDIYGFNNDLLDMIPQPVQAVIFLYPV------------------NFDNVWFIKQYIPNSCGTIALLHLYGNLRNKFELDKDSVLDDFFNKVNEMSAEKRGQELKNNKSIENLHHEFCGQVENRDDILDVDTHFIVFVQIEGKIIELDGRKDHPTVHCFTNGDNFLYDTGKIIQDKFIEKCKDDLRFSALAVIPN
Whole chain analysis

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Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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2.1m 5-153 149 1-4 157-204 154-156 4 48 slipknot
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3.1m 8-167 160 1-7 187-204 168-186 7 18 slipknot
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3.1m 5-186 182 1-4 198-204 187-197 4 7 slipknot
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2.1m 6-146 141 1-2, 154-204 3-5, 147-153 2 51 slipknot
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2.1m 8-187 180 1-4, 197-204 5-7, 188-196 4 8 slipknot
sequence length 222
structure length 204
publication title Characterization and Structural Studies of the Plasmodium Falciparum Ubiquitin and Nedd8 Hydrolase Uchl3.
pubmed doi rcsb
molecule tags Hydrolase/protein binding
molecule keywords UBIQUITIN CARBOXYL-TERMINAL HYDROLASE L3
source organism Plasmodium falciparum
missing residues 55-72
total genus Genus: 58
ec nomenclature ec 3.4.19.12: Ubiquitinyl hydrolase 1.
pdb deposition date 2009-03-26
KnotProt deposition date 2014-07-31
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
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#similar chains, but unknotted
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How to cite
KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling