2WITA

Crystal structure of the sodium-coupled glycine betaine symporter betp from corynebacterium glutamicum with bound substrate
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
  • Chain breaks within knot 41 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Genus: 171
Slipknot S +31 41 +31

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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 130-325 196 326-533 1-95 96-129 95 207 slipknot
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41 92-359 268 1-91 409-533 360-408 91 125 slipknot
Chain Sequence
SLNWSVIVPALVIVLATVVWGIGFKDSFTNFASSALSAVVDNLGWAFILFGTVFVFFIVVIAASKFGTIRLGRIDEAPEFRTVSWISMMFAAGMGIGLMFYGTTEPLTFYRNGVPGHDEHNVGVAMSTTMFHWTLHPWAIYAIVGLAIAYSTFRVGRKQLLSSAFVPLIGEKGAEGWLGKLIDILAIIATVFGTACSLGLGALQIGAGLSAANIIE--SDWTIVGIVSVLTLAFIFSAISGVGKGIQYLSNANMVLAALLAIFVFVVGPTVSILNLLPGSIGNYLSNFFQMAGRTAMSADGTAGEWLGSWTIFYWAWWISWSPFVGMFLARISRGRSIREFILGVLLVPAGVSTVWFSIFGGTAIVFEQNGESIWGDGAAEEQLFGLLHALPGGQIMGIIAMILLGTFFITSADSASTVMGTMSQHGQLEANKWVTAAWGVATAAIGLTLLLSGGDNALSNLQNVTIVAATPFLFVVIGLMFALVKDLSNDVIYLEYREQQRFNARLARERRVHNEHRKRELAAKRRRERKAS
Whole chain analysis

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Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.2 48-351 304 1-47 368-531 352-367 47 164 slipknot
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4.1 30-367 338 1-29 373-531 368-372 29 159 slipknot
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3.2 46-381 336 1-45 403-531 382-402 45 129 slipknot
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3.2 40-402 363 1-39 411-531 403-410 39 121 slipknot
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3.2 40-410 371 1-39 419-531 411-418 39 113 slipknot
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3.2 62-398 337 1-39, 411-531 40-61, 399-410 39 121 slipknot
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3.2 62-410 349 1-39, 419-531 40-61, 411-418 39 113 slipknot
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4.1 35-367 333 1-7, 382-531 8-34, 368-381 7 150 slipknot
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4.1 36-367 332 1-34, 382-531 35-35, 368-381 34 150 slipknot
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4.1 39-367 329 1-35, 373-531 36-38, 368-372 35 159 slipknot
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4.1 39-372 334 1-35, 382-531 36-38, 373-381 35 150 slipknot
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3.2 48-367 320 1-38, 373-531 39-47, 368-372 38 159 slipknot
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4.1 48-372 325 1-38, 382-531 39-47, 373-381 38 150 slipknot
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4.1 48-381 334 1-45, 383-531 46-47, 382-382 45 149 slipknot
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3.2 68-361 294 1-45, 396-531 46-67, 362-395 45 136 slipknot
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4.1 68-395 328 1-45, 399-531 46-67, 396-398 45 133 slipknot
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4.1 85-360 276 1-47, 399-531 48-84, 361-398 47 133 slipknot
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4.1 88-360 273 1-84, 399-531 85-87, 361-398 84 133 slipknot
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3.2 78-398 321 1-61, 400-531 62-77, 399-399 61 132 slipknot
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4.1 88-398 311 1-62, 407-531 63-87, 399-406 62 125 slipknot
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3.2 87-406 320 1-62, 411-531 63-86, 407-410 62 121 slipknot
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4.1 88-410 323 1-64, 412-531 65-87, 411-411 64 120 slipknot
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4.1 92-380 289 1-87, 404-531 88-91, 381-403 87 128 slipknot
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3.2 92-403 312 1-87, 406-531 88-91, 404-405 87 126 slipknot
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4.1 92-406 315 1-87, 411-531 88-91, 407-410 87 121 slipknot
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3.2 90-410 321 1-87, 412-531 88-89, 411-411 87 120 slipknot
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3.2 95-380 286 1-91, 404-531 92-94, 381-403 91 128 slipknot
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4.1 95-403 309 1-91, 407-531 92-94, 404-406 91 125 slipknot
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3.2 97-380 284 1-94, 401-531 95-96, 381-400 94 131 slipknot
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3.2 97-404 308 1-94, 406-531 95-96, 405-405 94 126 slipknot
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3.2 98-378 281 1-87, 395-531 88-97, 379-394 87 137 slipknot
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3.2 98-394 297 1-96, 400-531 97-97, 395-399 96 132 slipknot
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2.1 110-412 303 1-92, 451-531 93-109, 413-450 92 81 slipknot
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2.1 110-472 363 473-531 1-92 93-109 92 58 slipknot
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3.1 123-331 209 1-106, 347-531 107-122, 332-346 106 185 slipknot
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2.1 129-342 214 1-108, 355-531 109-128, 343-354 108 177 slipknot
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2.1 126-354 229 1-108, 360-531 109-125, 355-359 108 172 slipknot
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3.1 122-507 386 508-531 1-109 110-121 109 23 slipknot
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3.1 124-507 384 508-531 1-121 122-123 121 23 slipknot
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2.1 135-419 285 1-114, 471-531 115-134, 420-470 114 61 slipknot
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2.1 135-470 336 471-531 1-120 121-134 120 60 slipknot
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2.1 136-468 333 1-134, 529-531 135-135, 469-528 134 3 slipknot
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2.1 135-413 279 1-122, 420-531 123-134, 414-419 122 112 slipknot
sequence length 533
structure length 531
publication title K(+)-Induced Conformational Changes in the Trimeric Betaine Transporter Betp Monitored by Atr-Ftir Spectroscopy.
pubmed doi rcsb
molecule tags Membrane protein
molecule keywords GLYCINE BETAINE TRANSPORTER BETP
source organism Corynebacterium glutamicum
missing residues 217-218
total genus Genus: 171
ec nomenclature
pdb deposition date 2009-05-17
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02028 BCCT BCCT family transporter
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the pdb database (?% sequence similarity)

  
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How to cite
KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling