2XQ2A

Structure of the k294a mutant of vsglt
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
  • Chain breaks within knot 41 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Genus: 208
Slipknot S +31 41 +31

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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 74-264 191 265-565 1-57 58-73 57 300 slipknot
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41 53-295 243 1-52 358-565 296-357 52 208 slipknot
Chain Sequence
SFIDIMVFAIYVAIIIGVGLWV-------------------SLPWWAVGASLIAANISAEQFIGMSGSGYSIGLAIASYEWMSAITLIIVGKYFLPIFIEKGIYTIPEFVEKRFNKKLKTILAVFWISLYIFVNLTSVLYLGGLALETILGIPLMYSILGLALFALVYSIYGGVVWTDVIQVFFLVLGGFMT---TYMAVSFIGGTDGWFAGVSKMVDAAPGHFEMILDQSNPQYMNLPGIAVLIGGLWVANLYYWGFNQYIIQRTLAAKSVSEAQKGIVFAAFLALIVPFLVVLPGIAAYVITSDPQLMASLGNLPSAANADKAYPWLTQFLPVG-----VKGVVFAALAAAIVSSLASMLNSTATIFTMDIYKEYISPDSGDHKLVNVGRTAAVVALIIAALIAPMLGGIGQCFQYIQEYTGLVSPGILAVFLLGLFWKKTTSKGAIIGVVASIPFALFLKFMPLSMPFMDQMLYTLLFTMVVIAFTSLSTSINDDDPKGISVTSSMFVTDRSFNIAAYGIMIVLAVLYTLFWVNADAEITLIIFGVMAGVIGTILLISYGIK
Whole chain analysis

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Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.2 27-269 243 1-26 282-538 270-281 26 257 slipknot
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4.1 29-279 251 1-28 300-538 280-299 28 239 slipknot
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4.1 29-299 271 1-28 304-538 300-303 28 235 slipknot
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3.2 12-303 292 1-11 305-538 304-304 11 234 slipknot
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4.1 29-303 275 1-28 322-538 304-321 28 217 slipknot
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3.2 29-321 293 1-28 329-538 322-328 28 210 slipknot
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3.2 29-328 300 1-28 330-538 329-329 28 209 slipknot
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4.1 30-279 250 1-28, 300-538 29-29, 280-299 28 239 slipknot
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4.1 30-299 270 1-28, 304-538 29-29, 300-303 28 235 slipknot
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3.2 30-303 274 1-28, 310-538 29-29, 304-309 28 229 slipknot
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3.2 39-301 263 1-28, 326-538 29-38, 302-325 28 213 slipknot
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3.2m 35-299 265 1-29, 302-538 30-34, 300-301 29 237 slipknot
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3.2 40-301 262 1-38, 326-538 39-39, 302-325 38 213 slipknot
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3.2 39-287 249 1-30, 296-538 31-38, 288-295 30 243 slipknot
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2.1 43-336 294 1-32, 368-538 33-42, 337-367 32 171 slipknot
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2.1 64-331 268 1-33, 385-538 34-63, 332-384 33 154 slipknot
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2.1 41-500 460 1-33, 516-538 34-40, 501-515 33 23 slipknot
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2.1 65-412 348 1-36, 491-538 37-64, 413-490 36 48 slipknot
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2.1 52-529 478 530-538 1-39 40-51 39 8 slipknot
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1.1 62-264 203 1-46, 279-538 47-61, 265-278 46 260 slipknot
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2.1 62-245 184 1-52, 256-538 53-61, 246-255 52 283 slipknot
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2.1 62-523 462 524-538 1-52 53-61 52 14 slipknot
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1.1 61-237 177 1-53, 245-538 54-60, 238-244 53 294 slipknot
sequence length 565
structure length 538
publication title The Mechanism of Sodium and Substrate Release from the Binding Pocket of Vsglt
pubmed doi rcsb
molecule tags Transport protein
molecule keywords SODIUM/GLUCOSE COTRANSPORTER
source organism Vibrio parahaemolyticus
missing residues 23-41, 174-176, 315-319
total genus Genus: 208
ec nomenclature
pdb deposition date 2010-09-01
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00474 SSF Sodium:solute symporter family
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
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How to cite
KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling