2XQ2B

Structure of the k294a mutant of vsglt
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
  • Chain breaks within knot 41 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Slipknot S +31 41 +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 50-238 189 239-539 1-32 33-49 32 300 slipknot
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41 29-270 242 1-28 331-539 271-330 28 209 slipknot
Chain Sequence
XXXXXXXXXXXXXXXXLPWWAVGASLIAANISAEQFIGMSGSGYSIGLAIASYEWMSAITLIIVGKYFLPIFIEKGIYTIPEFVEKRFNKKLKTILAVFWISLYIFVNLTSVLYLGGLALETILGIPLMYSILGLALFALVYSIY------VWTDVIQVFFLVLGGFMTTYMAVSFIGGTDGWFASKMVDA--APGHFEMILDQSNPQYMNLPGIAVLIGGLWVANLYYWGFNQYIIQRTLAAKSVSEAQKGIVFAAFLALIVPFLVVLPGIAAYVITSDPQLMASLGDPSAANADK------AYPWLTQFLVKGVVFAALAAAIV---SSLASMLNSTATIFTMDIYKEYISPDSGDHKLVNVGRTAAVVALIIAALIAPMLGGIGQCFQYIQEYTGLVSPGILAVFLLGLFWKKTTSKGAIIGVVASIPFALFLKFMPLSMPFMDQMLYTLLFTMVVIAFTSLSTSINDDDPKGISVTSSMFVTDRSFNIAAYGIMIVLAVLYTLFWVNADAEITLIIFGVMAGVIGTILLISYGIK
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.2 23-257 235 1-22 270-522 258-269 22 253 slipknot
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4.1 24-269 246 1-23 287-522 270-286 23 236 slipknot
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4.1 19-293 275 1-18 307-522 294-306 18 216 slipknot
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3.2 19-306 288 1-18 314-522 307-313 18 209 slipknot
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4.1 12-286 275 1-2, 294-522 3-11, 287-293 2 229 slipknot
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3.2 30-286 257 1-15, 306-522 16-29, 287-305 15 217 slipknot
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3.2 33-287 255 1-29, 306-522 30-32, 288-305 29 217 slipknot
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3.2 34-301 268 1-21, 307-522 22-33, 302-306 21 216 slipknot
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3.2 30-260 231 1-23, 269-522 24-29, 261-268 23 254 slipknot
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3.2 31-272 242 1-24, 283-522 25-30, 273-282 24 240 slipknot
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2.1 54-315 262 1-24, 369-522 25-53, 316-368 24 154 slipknot
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1.1 34-251 218 1-28, 260-522 29-33, 252-259 28 263 slipknot
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2.1 58-388 331 1-28, 477-522 29-57, 389-476 28 46 slipknot
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2.1 47-224 178 1-30, 242-522 31-46, 225-241 30 281 slipknot
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2.1 44-512 469 513-522 1-31 32-43 31 9 slipknot
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2.1 43-243 201 1-36, 249-522 37-42, 244-248 36 274 slipknot
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1.1 44-251 208 1-37, 263-522 38-43, 252-262 37 260 slipknot
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1.1 57-253 197 1-45, 267-522 46-56, 254-266 45 256 slipknot
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2.1 53-509 457 510-522 1-45 46-52 45 12 slipknot
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2.1 54-224 171 1-47, 230-522 48-53, 225-229 47 293 slipknot
missing residues 146-151, 186-187, 290-295, 313-315
publication title The Mechanism of Sodium and Substrate Release from the Binding Pocket of Vsglt
pubmed doi rcsb
structure length 522
molecule tags Transport protein
source organism Vibrio parahaemolyticus
sequence length 539
total genus Genus: 193
molecule keywords SODIUM/GLUCOSE COTRANSPORTER
ec nomenclature
pdb deposition date 2010-09-01
KnotProt deposition date 2014-10-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00474 SSF Sodium:solute symporter family
B PF00474.12 SSF Sodium:solute symporter family
B PF01102.13 Glycophorin_A Glycophorin A
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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