3F8GA

The x-ray structure of a dimeric variant of human pancreatic ribonuclease with high cytotoxic and antitumor activities
Cysteine knot

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Loop Piercing
view details
40-c-58-b-110-c-95 26-b-84
Chain Sequence
KESRAKKFQRQHMDSDSSPSSSSTYCNLMMCCRKMTQGRCKPVNTFVHEPLVDVQNVCFQEKVTCKNGQGNCYKSNSSMHITDCRLTNGSRYPNCAYRTSPKERHIIVACGGSPYVPVHFDASVE
sequence length 125
structure length 125
publication title Structural features for the mechanism of antitumor action of a dimeric human pancreatic ribonuclease variant.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Ribonuclease pancreatic
source organism Homo sapiens
ec nomenclature ec 3.1.27.5: Pancreatic ribonuclease.
pdb deposition date 2008-11-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.130.10 Alpha Beta Roll P-30 Protein P-30 Protein 3f8gA00
1ANGA 8RSAB 1RUVA 3DICA 2G8QA 1RRAA 1AFKB 1TQ9A 3D6PB 3EV2A 2P43A 1A2WA 2J4TA 3LN8A 1U1BB 2NUIA 8RATA 1IZQA 1K59A 3PHNA 3RSPA 3LJDB 3EV0A 1AWZA 1GQVA 5RSAA 1O0OB 1RHBA 1RNQA 1Z7XZ 2XOGA 1Z6DA 5RATA 4RATA 1BZQD 2W5LA 1C0CA 2E3WA 2RATA 3DJVA 1JVVA 2W5GA 1C9VA 1O0FB 2G8RA 3JW1B 3D6QB 1YV7A 1B6VA 2G4WA 1Z6SB 1AFUB 1RBIA 3BCMB 3EUXB 3BCOB 1Z7XX 2W5KB 1O0HB 2AASA 3DH5A 1YV6A 1YV4A 1RNVA 1C9XA 1RNFB 1BZQB 2P45A 2P4AA 1DY5A 2E0OB 3LXOA 1SSBA 1RCAA 1KF3A 1R5DA 3FL1A 1RNOA 1TQ9B 3EV2B 2J4TB 3DJXA 1O0MA 1YMNA 1EIDA 2P6ZB 3DJPB 1OJ1A 3RN3A 3EV0B 9RATA 3OQZA 1ONCA 1W4PB 1KF8A 2XOGB 1Z6DB 3FL3A 1RNYA 2W5LB 1KVZA 1EOSB 2W5GB 3DXGA 1HI3A 3LJEA 2OQFD 3EV4B 3F8GA 2G8RB 1A4YB 2C02A 2E0JA 1W4OB 2W5MA 3EUYA 1H52A 2G4WB 3I7YA 2G4XA 3OR0A 1KF7A 3I7XA 1AGIA 3EV5B 1R5CA 2HKYA 1H8XA 3SRNA 3D6OA 1D5HB 2BLPA 1XPTA 3DI9A 3FKZA 2BLZA 1JN4B 1RBWA 2VQ9A 4SRNA 1DY5B 2P49A 1Y92A 3DIBA 1UN4A 1JVUA 1RBBB 1R5DB 2KB5A 1QWQA 2P7SA 1PU3A 1RNXA 3RSDA 1RNNE 1DYTB 3BCPC 3OQZB 1Z3ME 1RPFA 3D8YA 3RSKA 1GIOA 7RATA 2RLNE 3FL3B 1CJQB 1JVTA 3BCPA 2P46A 3OQYB 1N3ZA 1KF4A 3I6FA 3DXGB 2P4AC 1J80B 3F8GB 3RATA 6RSAA 9RSAA 11BGB 3EV1A 1RNDA 1KM9A 1LSQA 2E0JB 1R3MA 3I7WA 1HI2A 2OQFC 8RSAA 3EUYB 3EV6A 1KM8A 3OR0B 1BSRA 2G8QB 1EICA 1FS3A 1Z3LE 1R5CB 3D6PA 11BAA 2OQFA 1A2WB 3LN8B 3D6OB 3BCPD 1H0DC 1JS0C 1XPTB 1IZPA 1RHAA 3D8ZA 3D7BA 1RBHA 1RNZA 1XPSA 1A5QA 2P42C 1Y92B 1JS0A 3I6HA 1JVUB 1HI5A 2P47A 3DJVB 4RSKA 3EUZA 1N1XA 1O0FA 2P42A 1FEVB 1H1HA 1J81B 1QHCA 1A4YE 2OP2A 1K5AA 3DI8A 1CJRB 1GV7A 1C8WA 3D8YB 3DJOA 1B6VB 1AFLA 1Z6SA 1AFUA 1BELA 3BCPB 3EUXA 2QCAA 3FD7A 1RASA 2RNSA 1YMWA 9RSAB 1K2AA 3EV1B 1R3MB 1M58A 2BEXC 2C05A 2E0OA 3EV6B 3DH6A 3HG6A 3I6JA 2E0MA 1BSRB 1E21A 1O0NA 11BAB 3FL1B 2OQFB 2XOIA 2RNFA 2ZPOA 1EIEA 2GMKA 3DJQA 2BZZA 3DJXB 1O0MB 2P6ZA 4RSDA 1RBCA 3DJPA 3MZQA 3D8ZB 3D7BB 2P46C 1W4PA 1K5BA 3DXHA 7RSAA 1RBGA 1XPSB 3A1RA 1JS0B 1W4QA 1Y94A 1DFJE 1RSMA 1UN5A 1RNME 2E0LA 1RARA 1Z5FA 3EV3A 1EOSA 3EUZB 1KF5A 1DZAA 3EV4A 2BEXD 1QHCB 2W5IA 1RPHA 1EOWA 1W4OA 2K11A 1RNCA 1J82B 3DJOB 3FL0A 1AFLB 2W5MB 1Z3PE 1C0BA 1AFKA 3EV5A 3FD7B 1H8XB 1U1BA 2VQ8A 1SRNA 6RATA 1J7ZB 1RTBA 3FKZB 3LJDA 2APQA 1JN4A 1KF2A 3MZRA 1O0OA 2BWLA 3I67A 1HI4A 1RBBA 2E0MB 1HBYA 2Q4GZ 3DI7A 1QMTA 2XOIB 2RNFB 1RATA 3DJQB 1DYTA 2KB6A 1SSAA 2C01X 1RNWA 1H53A 3JW1A 1KH8A 1ROBA 1RBNA 2BWKA 3D6QA 3DXHB 1RNUA 1IZRA 1YMRA 1B1EA 2P48A 1SSCA 1W4QB 2P44A 1Y94B 1UN3A 1B1JA 2E0LB 1JVTB 3EV3B 3BCMA 3OQYA 3BCOA 2W5KA 1BZQC 2E33B 1O0HA 1DZAB 2Q4GX 1B1IA 2ANGA 2W5IB 1RPGA 11BGA 1D5EB 1LSQB 1RNFA 1D5DB 1BZQA 3FL0B
chains in the KnotProt database with same CATH superfamily
1ANGA 8RSAB 1RUVA 3DICA 2G8QA 1RRAA 1AFKB 1TQ9A 3D6PB 3EV2A 2P43A 1A2WA 2J4TA 3LN8A 1U1BB 2NUIA 8RATA 1IZQA 1K59A 3PHNA 3RSPA 3LJDB 3EV0A 1AWZA 1GQVA 5RSAA 1O0OB 1RHBA 1RNQA 1Z7XZ 2XOGA 1Z6DA 5RATA 4RATA 1BZQD 2W5LA 1C0CA 2E3WA 2RATA 3DJVA 1JVVA 2W5GA 1C9VA 1O0FB 2G8RA 3JW1B 3D6QB 1YV7A 1B6VA 2G4WA 1Z6SB 1AFUB 1RBIA 3BCMB 3EUXB 3BCOB 1Z7XX 2W5KB 1O0HB 2AASA 3DH5A 1YV6A 1YV4A 1RNVA 1C9XA 1RNFB 1BZQB 2P45A 2P4AA 1DY5A 2E0OB 3LXOA 1SSBA 1RCAA 1KF3A 1R5DA 3FL1A 1RNOA 1TQ9B 3EV2B 2J4TB 3DJXA 1O0MA 1YMNA 1EIDA 2P6ZB 3DJPB 1OJ1A 3RN3A 3EV0B 9RATA 3OQZA 1ONCA 1W4PB 1KF8A 2XOGB 1Z6DB 3FL3A 1RNYA 2W5LB 1KVZA 1EOSB 2W5GB 3DXGA 1HI3A 3LJEA 2OQFD 3EV4B 3F8GA 2G8RB 1A4YB 2C02A 2E0JA 1W4OB 2W5MA 3EUYA 1H52A 2G4WB 3I7YA 2G4XA 3OR0A 1KF7A 3I7XA 1AGIA 3EV5B 1R5CA 2HKYA 1H8XA 3SRNA 3D6OA 1D5HB 2BLPA 1XPTA 3DI9A 3FKZA 2BLZA 1JN4B 1RBWA 2VQ9A 4SRNA 1DY5B 2P49A 1Y92A 3DIBA 1UN4A 1JVUA 1RBBB 1R5DB 2KB5A 1QWQA 2P7SA 1PU3A 1RNXA 3RSDA 1RNNE 1DYTB 3BCPC 3OQZB 1Z3ME 1RPFA 3D8YA 3RSKA 1GIOA 7RATA 2RLNE 3FL3B 1CJQB 1JVTA 3BCPA 2P46A 3OQYB 1N3ZA 1KF4A 3I6FA 3DXGB 2P4AC 1J80B 3F8GB 3RATA 6RSAA 9RSAA 11BGB 3EV1A 1RNDA 1KM9A 1LSQA 2E0JB 1R3MA 3I7WA 1HI2A 2OQFC 8RSAA 3EUYB 3EV6A 1KM8A 3OR0B 1BSRA 2G8QB 1EICA 1FS3A 1Z3LE 1R5CB 3D6PA 11BAA 2OQFA 1A2WB 3LN8B 3D6OB 3BCPD 1H0DC 1JS0C 1XPTB 1IZPA 1RHAA 3D8ZA 3D7BA 1RBHA 1RNZA 1XPSA 1A5QA 2P42C 1Y92B 1JS0A 3I6HA 1JVUB 1HI5A 2P47A 3DJVB 4RSKA 3EUZA 1N1XA 1O0FA 2P42A 1FEVB 1H1HA 1J81B 1QHCA 1A4YE 2OP2A 1K5AA 3DI8A 1CJRB 1GV7A 1C8WA 3D8YB 3DJOA 1B6VB 1AFLA 1Z6SA 1AFUA 1BELA 3BCPB 3EUXA 2QCAA 3FD7A 1RASA 2RNSA 1YMWA 9RSAB 1K2AA 3EV1B 1R3MB 1M58A 2BEXC 2C05A 2E0OA 3EV6B 3DH6A 3HG6A 3I6JA 2E0MA 1BSRB 1E21A 1O0NA 11BAB 3FL1B 2OQFB 2XOIA 2RNFA 2ZPOA 1EIEA 2GMKA 3DJQA 2BZZA 3DJXB 1O0MB 2P6ZA 4RSDA 1RBCA 3DJPA 3MZQA 3D8ZB 3D7BB 2P46C 1W4PA 1K5BA 3DXHA 7RSAA 1RBGA 1XPSB 3A1RA 1JS0B 1W4QA 1Y94A 1DFJE 1RSMA 1UN5A 1RNME 2E0LA 1RARA 1Z5FA 3EV3A 1EOSA 3EUZB 1KF5A 1DZAA 3EV4A 2BEXD 1QHCB 2W5IA 1RPHA 1EOWA 1W4OA 2K11A 1RNCA 1J82B 3DJOB 3FL0A 1AFLB 2W5MB 1Z3PE 1C0BA 1AFKA 3EV5A 3FD7B 1H8XB 1U1BA 2VQ8A 1SRNA 6RATA 1J7ZB 1RTBA 3FKZB 3LJDA 2APQA 1JN4A 1KF2A 3MZRA 1O0OA 2BWLA 3I67A 1HI4A 1RBBA 2E0MB 1HBYA 2Q4GZ 3DI7A 1QMTA 2XOIB 2RNFB 1RATA 3DJQB 1DYTA 2KB6A 1SSAA 2C01X 1RNWA 1H53A 3JW1A 1KH8A 1ROBA 1RBNA 2BWKA 3D6QA 3DXHB 1RNUA 1IZRA 1YMRA 1B1EA 2P48A 1SSCA 1W4QB 2P44A 1Y94B 1UN3A 1B1JA 2E0LB 1JVTB 3EV3B 3BCMA 3OQYA 3BCOA 2W5KA 1BZQC 2E33B 1O0HA 1DZAB 2Q4GX 1B1IA 2ANGA 2W5IB 1RPGA 11BGA 1D5EB 1LSQB 1RNFA 1D5DB 1BZQA 3FL0B
chains in the KnotProt database with same CATH topology
1ANGA 8RSAB 1RUVA 3DICA 2G8QA 1RRAA 1AFKB 1TQ9A 3D6PB 3EV2A 2P43A 1A2WA 2J4TA 3LN8A 1U1BB 2NUIA 8RATA 1IZQA 1K59A 3PHNA 3RSPA 3LJDB 3EV0A 1AWZA 1GQVA 5RSAA 1O0OB 1RHBA 1RNQA 1Z7XZ 2XOGA 1Z6DA 5RATA 4RATA 1BZQD 2W5LA 1C0CA 2E3WA 2RATA 3DJVA 1JVVA 2W5GA 1C9VA 1O0FB 2G8RA 3JW1B 3D6QB 1YV7A 1B6VA 2G4WA 1Z6SB 1AFUB 1RBIA 3BCMB 3EUXB 3BCOB 1Z7XX 2W5KB 1O0HB 2AASA 3DH5A 1YV6A 1YV4A 1RNVA 1C9XA 1RNFB 1BZQB 2P45A 2P4AA 1DY5A 2E0OB 3LXOA 1SSBA 1RCAA 1KF3A 1R5DA 3FL1A 1RNOA 1TQ9B 3EV2B 2J4TB 3DJXA 1O0MA 1YMNA 1EIDA 2P6ZB 3DJPB 1OJ1A 3RN3A 3EV0B 9RATA 3OQZA 1ONCA 1W4PB 1KF8A 2XOGB 1Z6DB 3FL3A 1RNYA 2W5LB 1KVZA 1EOSB 2W5GB 3DXGA 1HI3A 3LJEA 2OQFD 3EV4B 3F8GA 2G8RB 1A4YB 2C02A 2E0JA 1W4OB 2W5MA 3EUYA 1H52A 2G4WB 3I7YA 2G4XA 3OR0A 1KF7A 3I7XA 1AGIA 3EV5B 1R5CA 2HKYA 1H8XA 3SRNA 3D6OA 1D5HB 2BLPA 1XPTA 3DI9A 3FKZA 2BLZA 1JN4B 1RBWA 2VQ9A 4SRNA 1DY5B 2P49A 1Y92A 3DIBA 1UN4A 1JVUA 1RBBB 1R5DB 2KB5A 1QWQA 2P7SA 1PU3A 1RNXA 3RSDA 1RNNE 1DYTB 3BCPC 3OQZB 1Z3ME 1RPFA 3D8YA 3RSKA 1GIOA 7RATA 2RLNE 3FL3B 1CJQB 1JVTA 3BCPA 2P46A 3OQYB 1N3ZA 1KF4A 3I6FA 3DXGB 2P4AC 1J80B 3F8GB 3RATA 6RSAA 9RSAA 11BGB 3EV1A 1RNDA 1KM9A 1LSQA 2E0JB 1R3MA 3I7WA 1HI2A 2OQFC 8RSAA 3EUYB 3EV6A 1KM8A 3OR0B 1BSRA 2G8QB 1EICA 1FS3A 1Z3LE 1R5CB 3D6PA 11BAA 2OQFA 1A2WB 3LN8B 3D6OB 3BCPD 1H0DC 1JS0C 1XPTB 1IZPA 1RHAA 3D8ZA 3D7BA 1RBHA 1RNZA 1XPSA 1A5QA 2P42C 1Y92B 1JS0A 3I6HA 1JVUB 1HI5A 2P47A 3DJVB 4RSKA 3EUZA 1N1XA 1O0FA 2P42A 1FEVB 1H1HA 1J81B 1QHCA 1A4YE 2OP2A 1K5AA 3DI8A 1CJRB 1GV7A 1C8WA 3D8YB 3DJOA 1B6VB 1AFLA 1Z6SA 1AFUA 1BELA 3BCPB 3EUXA 2QCAA 3FD7A 1RASA 2RNSA 1YMWA 9RSAB 1K2AA 3EV1B 1R3MB 1M58A 2BEXC 2C05A 2E0OA 3EV6B 3DH6A 3HG6A 3I6JA 2E0MA 1BSRB 1E21A 1O0NA 11BAB 3FL1B 2OQFB 2XOIA 2RNFA 2ZPOA 1EIEA 2GMKA 3DJQA 2BZZA 3DJXB 1O0MB 2P6ZA 4RSDA 1RBCA 3DJPA 3MZQA 3D8ZB 3D7BB 2P46C 1W4PA 1K5BA 3DXHA 7RSAA 1RBGA 1XPSB 3A1RA 1JS0B 1W4QA 1Y94A 1DFJE 1RSMA 1UN5A 1RNME 2E0LA 1RARA 1Z5FA 3EV3A 1EOSA 3EUZB 1KF5A 1DZAA 3EV4A 2BEXD 1QHCB 2W5IA 1RPHA 1EOWA 1W4OA 2K11A 1RNCA 1J82B 3DJOB 3FL0A 1AFLB 2W5MB 1Z3PE 1C0BA 1AFKA 3EV5A 3FD7B 1H8XB 1U1BA 2VQ8A 1SRNA 6RATA 1J7ZB 1RTBA 3FKZB 3LJDA 2APQA 1JN4A 1KF2A 3MZRA 1O0OA 2BWLA 3I67A 1HI4A 1RBBA 2E0MB 1HBYA 2Q4GZ 3DI7A 1QMTA 2XOIB 2RNFB 1RATA 3DJQB 1DYTA 2KB6A 1SSAA 2C01X 1RNWA 1H53A 3JW1A 1KH8A 1ROBA 1RBNA 2BWKA 3D6QA 3DXHB 1RNUA 1IZRA 1YMRA 1B1EA 2P48A 1SSCA 1W4QB 2P44A 1Y94B 1UN3A 1B1JA 2E0LB 1JVTB 3EV3B 3BCMA 3OQYA 3BCOA 2W5KA 1BZQC 2E33B 1O0HA 1DZAB 2Q4GX 1B1IA 2ANGA 2W5IB 1RPGA 11BGA 1D5EB 1LSQB 1RNFA 1D5DB 1BZQA 3FL0B
chains in the KnotProt database with same CATH homology

  
#chains in the KnotProt database with same CATH superfamily
 1ANG A;  8RSA B;  1RUV A;  3DIC A;  2G8Q A;  1RRA A;  1AFK B;  1TQ9 A;  3D6P B;  3EV2 A;  2P43 A;  1A2W A;  2J4T A;  3LN8 A;  1U1B B;  2NUI A;  8RAT A;  1IZQ A;  1K59 A;  3PHN A;  3RSP A;  3LJD B;  3EV0 A;  1AWZ A;  1GQV A;  5RSA A;  1O0O B;  1RHB A;  1RNQ A;  1Z7X Z;  2XOG A;  1Z6D A;  5RAT A;  4RAT A;  1BZQ D;  2W5L A;  1C0C A;  2E3W A;  2RAT A;  3DJV A;  1JVV A;  2W5G A;  1C9V A;  1O0F B;  2G8R A;  3JW1 B;  3D6Q B;  1YV7 A;  1B6V A;  2G4W A;  1Z6S B;  1AFU B;  1RBI A;  3BCM B;  3EUX B;  3BCO B;  1Z7X X;  2W5K B;  1O0H B;  2AAS A;  3DH5 A;  1YV6 A;  1YV4 A;  1RNV A;  1C9X A;  1RNF B;  1BZQ B;  2P45 A;  2P4A A;  1DY5 A;  2E0O B;  3LXO A;  1SSB A;  1RCA A;  1KF3 A;  1R5D A;  3FL1 A;  1RNO A;  1TQ9 B;  3EV2 B;  2J4T B;  3DJX A;  1O0M A;  1YMN A;  1EID A;  2P6Z B;  3DJP B;  1OJ1 A;  3RN3 A;  3EV0 B;  9RAT A;  3OQZ A;  1ONC A;  1W4P B;  1KF8 A;  2XOG B;  1Z6D B;  3FL3 A;  1RNY A;  2W5L B;  1KVZ A;  1EOS B;  2W5G B;  3DXG A;  1HI3 A;  3LJE A;  2OQF D;  3EV4 B;  3F8G A;  2G8R B;  1A4Y B;  2C02 A;  2E0J A;  1W4O B;  2W5M A;  3EUY A;  1H52 A;  2G4W B;  3I7Y A;  2G4X A;  3OR0 A;  1KF7 A;  3I7X A;  1AGI A;  3EV5 B;  1R5C A;  2HKY A;  1H8X A;  3SRN A;  3D6O A;  1D5H B;  2BLP A;  1XPT A;  3DI9 A;  3FKZ A;  2BLZ A;  1JN4 B;  1RBW A;  2VQ9 A;  4SRN A;  1DY5 B;  2P49 A;  1Y92 A;  3DIB A;  1UN4 A;  1JVU A;  1RBB B;  1R5D B;  2KB5 A;  1QWQ A;  2P7S A;  1PU3 A;  1RNX A;  3RSD A;  1RNN E;  1DYT B;  3BCP C;  3OQZ B;  1Z3M E;  1RPF A;  3D8Y A;  3RSK A;  1GIO A;  7RAT A;  2RLN E;  3FL3 B;  1CJQ B;  1JVT A;  3BCP A;  2P46 A;  3OQY B;  1N3Z A;  1KF4 A;  3I6F A;  3DXG B;  2P4A C;  1J80 B;  3F8G B;  3RAT A;  6RSA A;  9RSA A;  11BG B;  3EV1 A;  1RND A;  1KM9 A;  1LSQ A;  2E0J B;  1R3M A;  3I7W A;  1HI2 A;  2OQF C;  8RSA A;  3EUY B;  3EV6 A;  1KM8 A;  3OR0 B;  1BSR A;  2G8Q B;  1EIC A;  1FS3 A;  1Z3L E;  1R5C B;  3D6P A;  11BA A;  2OQF A;  1A2W B;  3LN8 B;  3D6O B;  3BCP D;  1H0D C;  1JS0 C;  1XPT B;  1IZP A;  1RHA A;  3D8Z A;  3D7B A;  1RBH A;  1RNZ A;  1XPS A;  1A5Q A;  2P42 C;  1Y92 B;  1JS0 A;  3I6H A;  1JVU B;  1HI5 A;  2P47 A;  3DJV B;  4RSK A;  3EUZ A;  1N1X A;  1O0F A;  2P42 A;  1FEV B;  1H1H A;  1J81 B;  1QHC A;  1A4Y E;  2OP2 A;  1K5A A;  3DI8 A;  1CJR B;  1GV7 A;  1C8W A;  3D8Y B;  3DJO A;  1B6V B;  1AFL A;  1Z6S A;  1AFU A;  1BEL A;  3BCP B;  3EUX A;  2QCA A;  3FD7 A;  1RAS A;  2RNS A;  1YMW A;  9RSA B;  1K2A A;  3EV1 B;  1R3M B;  1M58 A;  2BEX C;  2C05 A;  2E0O A;  3EV6 B;  3DH6 A;  3HG6 A;  3I6J A;  2E0M A;  1BSR B;  1E21 A;  1O0N A;  11BA B;  3FL1 B;  2OQF B;  2XOI A;  2RNF A;  2ZPO A;  1EIE A;  2GMK A;  3DJQ A;  2BZZ A;  3DJX B;  1O0M B;  2P6Z A;  4RSD A;  1RBC A;  3DJP A;  3MZQ A;  3D8Z B;  3D7B B;  2P46 C;  1W4P A;  1K5B A;  3DXH A;  7RSA A;  1RBG A;  1XPS B;  3A1R A;  1JS0 B;  1W4Q A;  1Y94 A;  1DFJ E;  1RSM A;  1UN5 A;  1RNM E;  2E0L A;  1RAR A;  1Z5F A;  3EV3 A;  1EOS A;  3EUZ B;  1KF5 A;  1DZA A;  3EV4 A;  2BEX D;  1QHC B;  2W5I A;  1RPH A;  1EOW A;  1W4O A;  2K11 A;  1RNC A;  1J82 B;  3DJO B;  3FL0 A;  1AFL B;  2W5M B;  1Z3P E;  1C0B A;  1AFK A;  3EV5 A;  3FD7 B;  1H8X B;  1U1B A;  2VQ8 A;  1SRN A;  6RAT A;  1J7Z B;  1RTB A;  3FKZ B;  3LJD A;  2APQ A;  1JN4 A;  1KF2 A;  3MZR A;  1O0O A;  2BWL A;  3I67 A;  1HI4 A;  1RBB A;  2E0M B;  1HBY A;  2Q4G Z;  3DI7 A;  1QMT A;  2XOI B;  2RNF B;  1RAT A;  3DJQ B;  1DYT A;  2KB6 A;  1SSA A;  2C01 X;  1RNW A;  1H53 A;  3JW1 A;  1KH8 A;  1ROB A;  1RBN A;  2BWK A;  3D6Q A;  3DXH B;  1RNU A;  1IZR A;  1YMR A;  1B1E A;  2P48 A;  1SSC A;  1W4Q B;  2P44 A;  1Y94 B;  1UN3 A;  1B1J A;  2E0L B;  1JVT B;  3EV3 B;  3BCM A;  3OQY A;  3BCO A;  2W5K A;  1BZQ C;  2E33 B;  1O0H A;  1DZA B;  2Q4G X;  1B1I A;  2ANG A;  2W5I B;  1RPG A;  11BG A;  1D5E B;  1LSQ B;  1RNF A;  1D5D B;  1BZQ A;  3FL0 B; 
#chains in the KnotProt database with same CATH topology
 1ANG A;  8RSA B;  1RUV A;  3DIC A;  2G8Q A;  1RRA A;  1AFK B;  1TQ9 A;  3D6P B;  3EV2 A;  2P43 A;  1A2W A;  2J4T A;  3LN8 A;  1U1B B;  2NUI A;  8RAT A;  1IZQ A;  1K59 A;  3PHN A;  3RSP A;  3LJD B;  3EV0 A;  1AWZ A;  1GQV A;  5RSA A;  1O0O B;  1RHB A;  1RNQ A;  1Z7X Z;  2XOG A;  1Z6D A;  5RAT A;  4RAT A;  1BZQ D;  2W5L A;  1C0C A;  2E3W A;  2RAT A;  3DJV A;  1JVV A;  2W5G A;  1C9V A;  1O0F B;  2G8R A;  3JW1 B;  3D6Q B;  1YV7 A;  1B6V A;  2G4W A;  1Z6S B;  1AFU B;  1RBI A;  3BCM B;  3EUX B;  3BCO B;  1Z7X X;  2W5K B;  1O0H B;  2AAS A;  3DH5 A;  1YV6 A;  1YV4 A;  1RNV A;  1C9X A;  1RNF B;  1BZQ B;  2P45 A;  2P4A A;  1DY5 A;  2E0O B;  3LXO A;  1SSB A;  1RCA A;  1KF3 A;  1R5D A;  3FL1 A;  1RNO A;  1TQ9 B;  3EV2 B;  2J4T B;  3DJX A;  1O0M A;  1YMN A;  1EID A;  2P6Z B;  3DJP B;  1OJ1 A;  3RN3 A;  3EV0 B;  9RAT A;  3OQZ A;  1ONC A;  1W4P B;  1KF8 A;  2XOG B;  1Z6D B;  3FL3 A;  1RNY A;  2W5L B;  1KVZ A;  1EOS B;  2W5G B;  3DXG A;  1HI3 A;  3LJE A;  2OQF D;  3EV4 B;  3F8G A;  2G8R B;  1A4Y B;  2C02 A;  2E0J A;  1W4O B;  2W5M A;  3EUY A;  1H52 A;  2G4W B;  3I7Y A;  2G4X A;  3OR0 A;  1KF7 A;  3I7X A;  1AGI A;  3EV5 B;  1R5C A;  2HKY A;  1H8X A;  3SRN A;  3D6O A;  1D5H B;  2BLP A;  1XPT A;  3DI9 A;  3FKZ A;  2BLZ A;  1JN4 B;  1RBW A;  2VQ9 A;  4SRN A;  1DY5 B;  2P49 A;  1Y92 A;  3DIB A;  1UN4 A;  1JVU A;  1RBB B;  1R5D B;  2KB5 A;  1QWQ A;  2P7S A;  1PU3 A;  1RNX A;  3RSD A;  1RNN E;  1DYT B;  3BCP C;  3OQZ B;  1Z3M E;  1RPF A;  3D8Y A;  3RSK A;  1GIO A;  7RAT A;  2RLN E;  3FL3 B;  1CJQ B;  1JVT A;  3BCP A;  2P46 A;  3OQY B;  1N3Z A;  1KF4 A;  3I6F A;  3DXG B;  2P4A C;  1J80 B;  3F8G B;  3RAT A;  6RSA A;  9RSA A;  11BG B;  3EV1 A;  1RND A;  1KM9 A;  1LSQ A;  2E0J B;  1R3M A;  3I7W A;  1HI2 A;  2OQF C;  8RSA A;  3EUY B;  3EV6 A;  1KM8 A;  3OR0 B;  1BSR A;  2G8Q B;  1EIC A;  1FS3 A;  1Z3L E;  1R5C B;  3D6P A;  11BA A;  2OQF A;  1A2W B;  3LN8 B;  3D6O B;  3BCP D;  1H0D C;  1JS0 C;  1XPT B;  1IZP A;  1RHA A;  3D8Z A;  3D7B A;  1RBH A;  1RNZ A;  1XPS A;  1A5Q A;  2P42 C;  1Y92 B;  1JS0 A;  3I6H A;  1JVU B;  1HI5 A;  2P47 A;  3DJV B;  4RSK A;  3EUZ A;  1N1X A;  1O0F A;  2P42 A;  1FEV B;  1H1H A;  1J81 B;  1QHC A;  1A4Y E;  2OP2 A;  1K5A A;  3DI8 A;  1CJR B;  1GV7 A;  1C8W A;  3D8Y B;  3DJO A;  1B6V B;  1AFL A;  1Z6S A;  1AFU A;  1BEL A;  3BCP B;  3EUX A;  2QCA A;  3FD7 A;  1RAS A;  2RNS A;  1YMW A;  9RSA B;  1K2A A;  3EV1 B;  1R3M B;  1M58 A;  2BEX C;  2C05 A;  2E0O A;  3EV6 B;  3DH6 A;  3HG6 A;  3I6J A;  2E0M A;  1BSR B;  1E21 A;  1O0N A;  11BA B;  3FL1 B;  2OQF B;  2XOI A;  2RNF A;  2ZPO A;  1EIE A;  2GMK A;  3DJQ A;  2BZZ A;  3DJX B;  1O0M B;  2P6Z A;  4RSD A;  1RBC A;  3DJP A;  3MZQ A;  3D8Z B;  3D7B B;  2P46 C;  1W4P A;  1K5B A;  3DXH A;  7RSA A;  1RBG A;  1XPS B;  3A1R A;  1JS0 B;  1W4Q A;  1Y94 A;  1DFJ E;  1RSM A;  1UN5 A;  1RNM E;  2E0L A;  1RAR A;  1Z5F A;  3EV3 A;  1EOS A;  3EUZ B;  1KF5 A;  1DZA A;  3EV4 A;  2BEX D;  1QHC B;  2W5I A;  1RPH A;  1EOW A;  1W4O A;  2K11 A;  1RNC A;  1J82 B;  3DJO B;  3FL0 A;  1AFL B;  2W5M B;  1Z3P E;  1C0B A;  1AFK A;  3EV5 A;  3FD7 B;  1H8X B;  1U1B A;  2VQ8 A;  1SRN A;  6RAT A;  1J7Z B;  1RTB A;  3FKZ B;  3LJD A;  2APQ A;  1JN4 A;  1KF2 A;  3MZR A;  1O0O A;  2BWL A;  3I67 A;  1HI4 A;  1RBB A;  2E0M B;  1HBY A;  2Q4G Z;  3DI7 A;  1QMT A;  2XOI B;  2RNF B;  1RAT A;  3DJQ B;  1DYT A;  2KB6 A;  1SSA A;  2C01 X;  1RNW A;  1H53 A;  3JW1 A;  1KH8 A;  1ROB A;  1RBN A;  2BWK A;  3D6Q A;  3DXH B;  1RNU A;  1IZR A;  1YMR A;  1B1E A;  2P48 A;  1SSC A;  1W4Q B;  2P44 A;  1Y94 B;  1UN3 A;  1B1J A;  2E0L B;  1JVT B;  3EV3 B;  3BCM A;  3OQY A;  3BCO A;  2W5K A;  1BZQ C;  2E33 B;  1O0H A;  1DZA B;  2Q4G X;  1B1I A;  2ANG A;  2W5I B;  1RPG A;  11BG A;  1D5E B;  1LSQ B;  1RNF A;  1D5D B;  1BZQ A;  3FL0 B; 
#chains in the KnotProt database with same CATH homology
 1ANG A;  8RSA B;  1RUV A;  3DIC A;  2G8Q A;  1RRA A;  1AFK B;  1TQ9 A;  3D6P B;  3EV2 A;  2P43 A;  1A2W A;  2J4T A;  3LN8 A;  1U1B B;  2NUI A;  8RAT A;  1IZQ A;  1K59 A;  3PHN A;  3RSP A;  3LJD B;  3EV0 A;  1AWZ A;  1GQV A;  5RSA A;  1O0O B;  1RHB A;  1RNQ A;  1Z7X Z;  2XOG A;  1Z6D A;  5RAT A;  4RAT A;  1BZQ D;  2W5L A;  1C0C A;  2E3W A;  2RAT A;  3DJV A;  1JVV A;  2W5G A;  1C9V A;  1O0F B;  2G8R A;  3JW1 B;  3D6Q B;  1YV7 A;  1B6V A;  2G4W A;  1Z6S B;  1AFU B;  1RBI A;  3BCM B;  3EUX B;  3BCO B;  1Z7X X;  2W5K B;  1O0H B;  2AAS A;  3DH5 A;  1YV6 A;  1YV4 A;  1RNV A;  1C9X A;  1RNF B;  1BZQ B;  2P45 A;  2P4A A;  1DY5 A;  2E0O B;  3LXO A;  1SSB A;  1RCA A;  1KF3 A;  1R5D A;  3FL1 A;  1RNO A;  1TQ9 B;  3EV2 B;  2J4T B;  3DJX A;  1O0M A;  1YMN A;  1EID A;  2P6Z B;  3DJP B;  1OJ1 A;  3RN3 A;  3EV0 B;  9RAT A;  3OQZ A;  1ONC A;  1W4P B;  1KF8 A;  2XOG B;  1Z6D B;  3FL3 A;  1RNY A;  2W5L B;  1KVZ A;  1EOS B;  2W5G B;  3DXG A;  1HI3 A;  3LJE A;  2OQF D;  3EV4 B;  3F8G A;  2G8R B;  1A4Y B;  2C02 A;  2E0J A;  1W4O B;  2W5M A;  3EUY A;  1H52 A;  2G4W B;  3I7Y A;  2G4X A;  3OR0 A;  1KF7 A;  3I7X A;  1AGI A;  3EV5 B;  1R5C A;  2HKY A;  1H8X A;  3SRN A;  3D6O A;  1D5H B;  2BLP A;  1XPT A;  3DI9 A;  3FKZ A;  2BLZ A;  1JN4 B;  1RBW A;  2VQ9 A;  4SRN A;  1DY5 B;  2P49 A;  1Y92 A;  3DIB A;  1UN4 A;  1JVU A;  1RBB B;  1R5D B;  2KB5 A;  1QWQ A;  2P7S A;  1PU3 A;  1RNX A;  3RSD A;  1RNN E;  1DYT B;  3BCP C;  3OQZ B;  1Z3M E;  1RPF A;  3D8Y A;  3RSK A;  1GIO A;  7RAT A;  2RLN E;  3FL3 B;  1CJQ B;  1JVT A;  3BCP A;  2P46 A;  3OQY B;  1N3Z A;  1KF4 A;  3I6F A;  3DXG B;  2P4A C;  1J80 B;  3F8G B;  3RAT A;  6RSA A;  9RSA A;  11BG B;  3EV1 A;  1RND A;  1KM9 A;  1LSQ A;  2E0J B;  1R3M A;  3I7W A;  1HI2 A;  2OQF C;  8RSA A;  3EUY B;  3EV6 A;  1KM8 A;  3OR0 B;  1BSR A;  2G8Q B;  1EIC A;  1FS3 A;  1Z3L E;  1R5C B;  3D6P A;  11BA A;  2OQF A;  1A2W B;  3LN8 B;  3D6O B;  3BCP D;  1H0D C;  1JS0 C;  1XPT B;  1IZP A;  1RHA A;  3D8Z A;  3D7B A;  1RBH A;  1RNZ A;  1XPS A;  1A5Q A;  2P42 C;  1Y92 B;  1JS0 A;  3I6H A;  1JVU B;  1HI5 A;  2P47 A;  3DJV B;  4RSK A;  3EUZ A;  1N1X A;  1O0F A;  2P42 A;  1FEV B;  1H1H A;  1J81 B;  1QHC A;  1A4Y E;  2OP2 A;  1K5A A;  3DI8 A;  1CJR B;  1GV7 A;  1C8W A;  3D8Y B;  3DJO A;  1B6V B;  1AFL A;  1Z6S A;  1AFU A;  1BEL A;  3BCP B;  3EUX A;  2QCA A;  3FD7 A;  1RAS A;  2RNS A;  1YMW A;  9RSA B;  1K2A A;  3EV1 B;  1R3M B;  1M58 A;  2BEX C;  2C05 A;  2E0O A;  3EV6 B;  3DH6 A;  3HG6 A;  3I6J A;  2E0M A;  1BSR B;  1E21 A;  1O0N A;  11BA B;  3FL1 B;  2OQF B;  2XOI A;  2RNF A;  2ZPO A;  1EIE A;  2GMK A;  3DJQ A;  2BZZ A;  3DJX B;  1O0M B;  2P6Z A;  4RSD A;  1RBC A;  3DJP A;  3MZQ A;  3D8Z B;  3D7B B;  2P46 C;  1W4P A;  1K5B A;  3DXH A;  7RSA A;  1RBG A;  1XPS B;  3A1R A;  1JS0 B;  1W4Q A;  1Y94 A;  1DFJ E;  1RSM A;  1UN5 A;  1RNM E;  2E0L A;  1RAR A;  1Z5F A;  3EV3 A;  1EOS A;  3EUZ B;  1KF5 A;  1DZA A;  3EV4 A;  2BEX D;  1QHC B;  2W5I A;  1RPH A;  1EOW A;  1W4O A;  2K11 A;  1RNC A;  1J82 B;  3DJO B;  3FL0 A;  1AFL B;  2W5M B;  1Z3P E;  1C0B A;  1AFK A;  3EV5 A;  3FD7 B;  1H8X B;  1U1B A;  2VQ8 A;  1SRN A;  6RAT A;  1J7Z B;  1RTB A;  3FKZ B;  3LJD A;  2APQ A;  1JN4 A;  1KF2 A;  3MZR A;  1O0O A;  2BWL A;  3I67 A;  1HI4 A;  1RBB A;  2E0M B;  1HBY A;  2Q4G Z;  3DI7 A;  1QMT A;  2XOI B;  2RNF B;  1RAT A;  3DJQ B;  1DYT A;  2KB6 A;  1SSA A;  2C01 X;  1RNW A;  1H53 A;  3JW1 A;  1KH8 A;  1ROB A;  1RBN A;  2BWK A;  3D6Q A;  3DXH B;  1RNU A;  1IZR A;  1YMR A;  1B1E A;  2P48 A;  1SSC A;  1W4Q B;  2P44 A;  1Y94 B;  1UN3 A;  1B1J A;  2E0L B;  1JVT B;  3EV3 B;  3BCM A;  3OQY A;  3BCO A;  2W5K A;  1BZQ C;  2E33 B;  1O0H A;  1DZA B;  2Q4G X;  1B1I A;  2ANG A;  2W5I B;  1RPG A;  11BG A;  1D5E B;  1LSQ B;  1RNF A;  1D5D B;  1BZQ A;  3FL0 B;
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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