3F3AA

Crystal structure of leut bound to l-tryptophan and sodium
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
  • Chain breaks within knot 41 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Slipknot S +31 41 +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 37-264 228 265-507 1-20 21-36 20 242 slipknot
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41 13-297 285 1-12 349-507 298-348 12 159 slipknot
Chain Sequence
REHWATRLGLILAMAGNAVGLGNFLRFPVQAAENGGGAFMIPYIIAFLLVGIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVVAIYYVYIESWTLGFAIKFLVGLVPEPP---TDPDSILRPFKEFLYSYIGVPKGDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFTLSLGFGAIITYASYVRKDQDIVLSGLTAATLNEKAEVILGGSISIPAAVAFFGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLTSSIAIMQPMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFWAGTIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRYITPAFLAVLLVVWAREYIPKIMEETHWTVWITRFYIIGLFLFLTFLVFLAERRRNHE
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.2 10-287 278 1-9 301-504 288-300 9 204 slipknot
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4.1 13-298 286 1-12 306-504 299-305 12 199 slipknot
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4.1 13-305 293 1-12 308-504 306-307 12 197 slipknot
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3.2 7-310 304 1-6 317-504 311-316 6 188 slipknot
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3.2 14-334 321 1-13 349-504 335-348 13 156 slipknot
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4.1 10-308 299 1-2, 315-504 3-9, 309-314 2 190 slipknot
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2.1 22-411 390 1-15, 425-504 16-21, 412-424 15 80 slipknot
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1.1 40-273 234 1-16, 293-504 17-39, 274-292 16 212 slipknot
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2.1 40-408 369 409-504 1-16 17-39 16 95 slipknot
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2.1 41-352 312 1-18, 399-504 19-40, 353-398 18 106 slipknot
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2.1 39-255 217 1-20, 273-504 21-38, 256-272 20 232 slipknot
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1.1 36-242 207 1-21, 256-504 22-35, 243-255 21 249 slipknot
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1.1 38-242 205 1-35, 256-504 36-37, 243-255 35 249 slipknot
missing residues 128-130
publication title A competitive inhibitor traps LeuT in an open-to-out conformation.
pubmed doi rcsb
structure length 504
molecule tags Transport protein
source organism Aquifex aeolicus
sequence length 507
total genus Genus: 215
molecule keywords Transporter
ec nomenclature
pdb deposition date 2008-10-30
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00209 SNF Sodium:neurotransmitter symporter family
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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