3F3DA

Crystal structure of leut bound to l-methionine and sodium
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
  • Chain breaks within knot 41 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Genus: 207
Slipknot S +31 41 +31

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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 40-261 222 262-511 1-21 22-39 21 249 slipknot
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41 13-293 281 1-12 350-511 294-349 12 162 slipknot
Chain Sequence
REHWATRLGLILAMAGNAVGLGNFLRFPVQAAENGGGAFMIPYIIAFLLVGIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVVAIYYVYIESWTLGFAIKFLVGLVPEPPP--TDPDSILRPFKEFLYSYIGVPKGDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFTLSLGFGAIITYASYVRKDQDIVLSGLTAATLNEKAEVILGGSISIPAAVAFFGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLTSSIAIMQPMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFWAGTIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRYITPAFLAVLLVVWAREYIPKIMEETHWTVWITRFYIIGLFLFLTFLVFLAERRRNHESAGT
Whole chain analysis

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Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.2m 11-287 277 1-10 300-509 288-299 10 210 slipknot
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4.1 10-299 290 1-9 312-509 300-311 9 198 slipknot
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4.1 9-319 311 1-8 325-509 320-324 8 185 slipknot
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4.1 7-326 320 1-6 332-509 327-331 6 178 slipknot
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3.2 15-333 319 1-14 349-509 334-348 14 161 slipknot
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2.1 32-411 380 1-17, 438-509 18-31, 412-437 17 72 slipknot
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2.1 32-254 223 1-18, 269-509 19-31, 255-268 18 241 slipknot
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2.1 32-268 237 1-18, 274-509 19-31, 269-273 18 236 slipknot
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2.1 43-353 311 1-18, 401-509 19-42, 354-400 18 109 slipknot
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2.1 42-409 368 410-509 1-18 19-41 18 99 slipknot
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1.1 39-246 208 1-26, 255-509 27-38, 247-254 26 255 slipknot
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2.1 35-254 220 1-31, 259-509 32-34, 255-258 31 251 slipknot
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2.1 38-254 217 1-34, 259-509 35-37, 255-258 34 251 slipknot
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2.1 42-274 233 1-30, 292-509 31-41, 275-291 30 218 slipknot
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2.1 41-261 221 1-34, 271-509 35-40, 262-270 34 239 slipknot
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2.1 42-401 360 1-35, 409-509 36-41, 402-408 35 101 slipknot
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2.1 42-261 220 1-40, 264-509 41-41, 262-263 40 246 slipknot
sequence length 511
structure length 509
publication title A competitive inhibitor traps LeuT in an open-to-out conformation.
pubmed doi rcsb
molecule tags Transport protein
molecule keywords Transporter
source organism Aquifex aeolicus
missing residues 129-130
total genus Genus: 207
ec nomenclature
pdb deposition date 2008-10-30
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00209 SNF Sodium:neurotransmitter symporter family
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
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How to cite
KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling