3F48A

Crystal structure of leut bound to l-alanine and sodium
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
  • Chain breaks within knot 41 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Slipknot S +31 41 +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 40-259 220 260-511 1-20 21-39 20 251 slipknot
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41 13-293 281 1-12 349-511 294-348 12 163 slipknot
Chain Sequence
REHWATRLGLILAMAGNAVGLGNFLRFPVQAAENGGGAFMIPYIIAFLLVGIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVVAIYYVYIESWTLGFAIKFLVGLVPEPPP--TDPDSILRPFKEFLYSYIGVPKGDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFTLSLGFGAIITYASYVRKDQDIVLSGLTAATLNEKAEVILGGSISIPAAVAFFGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLTSSIAIMQPMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFWAGTIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRYITPAFLAVLLVVWAREYIPKIMEETHWTVWITRFYIIGLFLFLTFLVFLAERRRNHESAGT
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.2 11-287 277 1-10 301-509 288-300 10 209 slipknot
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4.1 9-300 292 1-8 312-509 301-311 8 198 slipknot
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4.1 8-321 314 1-7 327-509 322-326 7 183 slipknot
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3.2 13-331 319 1-12 349-509 332-348 12 161 slipknot
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2.1 24-274 251 1-16, 285-509 17-23, 275-284 16 225 slipknot
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2.1 31-254 224 1-19, 267-509 20-30, 255-266 19 243 slipknot
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2.1 25-454 430 1-19, 462-509 20-24, 455-461 19 48 slipknot
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2.1 41-410 370 1-20, 480-509 21-40, 411-479 20 30 slipknot
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1.1 35-244 210 1-22, 253-509 23-34, 245-252 22 257 slipknot
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2.1 41-274 234 1-23, 285-509 24-40, 275-284 23 225 slipknot
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3.1 37-262 226 1-31, 269-509 32-36, 263-268 31 241 slipknot
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2.1 41-258 218 1-33, 272-509 34-40, 259-271 33 238 slipknot
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2.1 41-271 231 1-33, 274-509 34-40, 272-273 33 236 slipknot
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2.1 42-262 221 1-40, 273-509 41-41, 263-272 40 237 slipknot
missing residues 129-130
publication title A competitive inhibitor traps LeuT in an open-to-out conformation.
pubmed doi rcsb
structure length 509
molecule tags Transport protein
source organism Aquifex aeolicus
sequence length 511
total genus Genus: 211
molecule keywords Transporter
ec nomenclature
pdb deposition date 2008-10-31
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00209 SNF Sodium:neurotransmitter symporter family
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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