3HFXA

Crystal structure of carnitine transporter
Slipknot S +31 41 +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 128-319 192 320-493 1-91 92-127 91 173 slipknot
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41 87-354 268 1-86 410-493 355-409 86 84 slipknot
Chain Sequence
PKVFFPPLIIVGILCWLTVRDLDAANVVINAVFSYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGNEPPEFSTASWIFMMFASCTSAAVLFWGSIEIYYYISTPPFGLEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFAYFFFVRKMEVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTECMQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIVSGASFIMNYFTDSVGMLLMYLPRMLFYTDPIAKGGFPQGWTVFYWAWWVIYAIQMSIFLARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLLLIDKNIINIPNLIEQYGVARAIIETWAALPLSTATMWGFFILCFIATVTLVNACSYTLAMSTCREVRDGEEPPLLVRIGWSILVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKQNWKD
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.2 51-346 296 1-50 361-493 347-360 50 133 slipknot
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4.1 52-363 312 1-51 403-493 364-402 51 91 slipknot
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4.1 41-402 362 1-40 414-493 403-413 40 80 slipknot
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3.2 39-413 375 1-1, 415-493 2-38, 414-414 1 79 slipknot
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3.2 69-357 289 1-28, 403-493 29-68, 358-402 28 91 slipknot
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4.1 69-402 334 1-40, 405-493 41-68, 403-404 40 89 slipknot
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3.2 71-357 287 1-68, 403-493 69-70, 358-402 68 91 slipknot
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4.1 71-402 332 1-68, 405-493 69-70, 403-404 68 89 slipknot
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4.1 73-357 285 1-70, 403-493 71-72, 358-402 70 91 slipknot
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4.1 73-402 330 1-70, 405-493 71-72, 403-404 70 89 slipknot
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3.2 75-357 283 1-72, 403-493 73-74, 358-402 72 91 slipknot
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4.1 78-357 280 1-74, 403-493 75-77, 358-402 74 91 slipknot
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4.1 83-357 275 1-77, 403-493 78-82, 358-402 77 91 slipknot
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3.2 92-379 288 1-74, 405-493 75-91, 380-404 74 89 slipknot
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3.2 93-383 291 1-91, 399-493 92-92, 384-398 91 95 slipknot
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2.1 110-411 302 1-87, 447-493 88-109, 412-446 87 47 slipknot
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2.1 102-478 377 479-493 1-87 88-101 87 14 slipknot
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2.1 122-314 193 1-104, 327-493 105-121, 315-326 104 167 slipknot
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2.1 122-340 219 1-104, 356-493 105-121, 341-355 104 138 slipknot
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3.1 123-419 297 1-109, 433-493 110-122, 420-432 109 61 slipknot
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3.1 123-432 310 1-109, 442-493 110-122, 433-441 109 52 slipknot
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3.1 122-466 345 1-107, 480-493 108-121, 467-479 107 14 slipknot
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3.1 124-481 358 482-493 1-111 112-123 111 11 slipknot
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2.1 132-410 279 1-116, 462-493 117-131, 411-461 116 32 slipknot
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2.1 132-461 330 1-116, 478-493 117-131, 462-477 116 16 slipknot
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2.1 133-436 304 1-131, 478-493 132-132, 437-477 131 16 slipknot
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3.1 134-436 303 1-132, 475-493 133-133, 437-474 132 19 slipknot
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2.1 133-477 345 478-493 1-120 121-132 120 15 slipknot
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2.1 134-325 192 1-121, 340-493 122-133, 326-339 121 154 slipknot
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1.1 134-341 208 1-121, 357-493 122-133, 342-356 121 137 slipknot
sequence length 493
structure length 493
publication title Crystal structure of the carnitine transporter and insights into the antiport mechanism
pubmed doi rcsb
molecule tags Transport protein
molecule keywords L-carnitine/gamma-butyrobetaine antiporter
source organism Escherichia coli
total genus Genus: 164
ec nomenclature
pdb deposition date 2009-05-13
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02028 BCCT BCCT family transporter
Image from the rcsb pdb (www.rcsb.org)
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