3OIJA

Crystal structure of saccharomyces cerevisiae nep1/emg1 bound to s-adenosylhomocysteine and 2 molecules of cognate rna
Knot K +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 152-197 46 1-151, 198-225 151 28 knot
Chain Sequence
PPVLTSKDKITKRMIVVLAMASLETHKI---------YVLLNCDDHQGLLDISEARPDI-----THQCLLTLLDSPINKAGKLQVYIQTSRGILIEVNPTVRIPRTFKRFSGLMVQLLHKLSIRSVNSEEKLLKVIKNPITDHLPTKCRKVTLSFDAPVIRVQDYIEKLDDDESICVFVGAMARGKDNFADEYVDEKVGLSNYPLSASVACSKFCHGAEDAWNIL
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.1 138-185 48 1-137, 186-211 137 26 knot
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2.1 136-181 46 1-135 187-211 182-186 135 25 slipknot
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2.1 140-196 57 1-137, 205-211 138-139, 197-204 137 7 slipknot
missing residues 29-37, 51-55
publication title Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis.
pubmed doi rcsb
structure length 211
molecule tags Ribosomal protein
source organism Saccharomyces cerevisiae
sequence length 225
total genus Genus: 62
molecule keywords Essential for mitotic growth 1
ec nomenclature ec 2.1.1.260: rRNA small subunit pseudouridine methyltransferase Nep1.
pdb deposition date 2010-08-19
KnotProt deposition date 2014-07-31
Image from the rcsb pdb (www.rcsb.org)
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