3TT3A

Crystal structure of leut in the inward-open conformation in complex with fab
Slipknot S +31 41 +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 33-257 225 258-501 1-18 19-32 18 243 slipknot
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41 12-288 277 1-11 341-501 289-340 11 161 slipknot
Chain Sequence
RLGLILAMAGNAVGLGNFLRFPVQAAENGGGAFMIPYIIAFLLVGIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVVAIYYVYIESWTLGFAIKFLVGLVPEPPPNATDPDSILRPFKEFLYSYIGVPKGDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFTLSLGFGAIITYASAVRKDQDIVLSGLTAATLNEAAEVILGGSISIPAAVAFFGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLVASIAIMQPMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFWAGTIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRYITPAFLAVLLVVWAREYIPKIMEETHWTVWITRFYIIGLFLFLTFLVFLAERRRNHE
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.2 9-283 275 1-8 292-501 284-291 8 210 slipknot
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4.1 7-295 289 1-6 304-501 296-303 6 198 slipknot
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4.1 7-321 315 1-6 331-501 322-330 6 171 slipknot
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3.2 11-325 315 1-10 342-501 326-341 10 160 slipknot
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3.2 11-291 281 1-4, 297-501 5-10, 292-296 4 205 slipknot
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3.2 12-317 306 1-4, 323-501 5-11, 318-322 4 179 slipknot
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3.2 12-322 311 1-6, 326-501 7-11, 323-325 6 176 slipknot
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3.2 12-325 314 1-10, 330-501 11-11, 326-329 10 172 slipknot
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2.1 23-435 413 1-12, 458-501 13-22, 436-457 12 44 slipknot
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2.1 23-477 455 1-12, 495-501 13-22, 478-494 12 7 slipknot
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2.1 28-253 226 1-13, 271-501 14-27, 254-270 13 231 slipknot
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2.1 20-411 392 1-13, 421-501 14-19, 412-420 13 81 slipknot
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1.1 33-238 206 1-15, 250-501 16-32, 239-249 15 252 slipknot
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2.1 35-410 376 411-501 1-15 16-34 15 90 slipknot
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2.1 36-346 311 1-16, 387-501 17-35, 347-386 16 115 slipknot
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1.1 35-270 236 1-19, 290-501 20-34, 271-289 19 212 slipknot
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3.1 30-259 230 1-27, 271-501 28-29, 260-270 27 231 slipknot
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3.1 31-259 229 1-29, 271-501 30-30, 260-270 29 231 slipknot
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2.1 35-256 222 1-28, 269-501 29-34, 257-268 28 233 slipknot
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2.1 36-259 224 1-34, 268-501 35-35, 260-267 34 234 slipknot
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2.1 35-268 234 1-30, 271-501 31-34, 269-270 30 231 slipknot
sequence length 501
structure length 501
publication title X-ray structures of LeuT in substrate-free outward-open and apo inward-open states.
pubmed doi rcsb
molecule tags Transport protein
molecule keywords Leucine transporter LeuT
source organism Aquifex aeolicus
total genus Genus: 174
ec nomenclature
pdb deposition date 2011-09-13
KnotProt deposition date 2014-08-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00209 SNF Sodium:neurotransmitter symporter family
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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