3TU0A

Crystal structure of t355v, s354a, k288a leut mutant in complex with alanine and sodium
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
  • Chain breaks within knot 41 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Slipknot S +31 41 +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 38-261 224 262-511 1-20 21-37 20 249 slipknot
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41 13-293 281 1-12 346-511 294-345 12 166 slipknot
Chain Sequence
REHWATRLGLILAMAGNAVGLGNFLRFPVQAAENGGGAFMIPYIIAFLLVGIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVVAIYYVYIESWTLGFAIKFLVGLVPEPPP--TDPDSILRPFKEFLYSYIGVPKGDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFTLSLGFGAIITYASYVRKDQDIVLSGLTAATLNEAAEVILGGSISIPAAVAFFGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLVASIAIMQPMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFWAGTIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRYITPAFLAVLLVVWAREYIPKIMEETHWTVWITRFYIIGLFLFLTFLVFLAERRRNHESAGT
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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2.3 14-287 274 1-13 301-509 288-300 13 209 slipknot
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4.1 9-300 292 1-8 306-509 301-305 8 204 slipknot
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3.2 12-300 289 1-11 313-509 301-312 11 197 slipknot
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3.2 8-313 306 1-7 320-509 314-319 7 190 slipknot
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3.2 16-331 316 1-15 350-509 332-349 15 160 slipknot
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2.1 29-254 226 1-17, 268-509 18-28, 255-267 17 242 slipknot
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2.1 25-269 245 1-17, 275-509 18-24, 270-274 17 235 slipknot
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2.1 33-418 386 1-18, 455-509 19-32, 419-454 18 55 slipknot
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2.1 31-454 424 1-20, 481-509 21-30, 455-480 20 29 slipknot
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2.1 44-406 363 407-509 1-21 22-43 21 102 slipknot
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1.1 39-243 205 1-22, 252-509 23-38, 244-251 22 258 slipknot
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1.1 39-251 213 1-22, 258-509 23-38, 252-257 22 252 slipknot
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2.1 33-280 248 1-26, 290-509 27-32, 281-289 26 220 slipknot
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2.1 38-260 223 1-28, 270-509 29-37, 261-269 28 240 slipknot
missing residues 129-130
publication title X-ray structures of LeuT in substrate-free outward-open and apo inward-open states.
pubmed doi rcsb
structure length 509
molecule tags Transport protein
source organism Aquifex aeolicus
sequence length 511
total genus Genus: 194
molecule keywords Leucine transporter LeuT
ec nomenclature
pdb deposition date 2011-09-15
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00209 SNF Sodium:neurotransmitter symporter family
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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