3USGA

Crystal structure of leut bound to l-leucine in space group c2 from lipid bicelles
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
  • Chain breaks within knot 41 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Slipknot S +31 41 +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 36-260 225 261-505 1-23 24-35 23 244 slipknot
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41 12-294 283 1-11 346-505 295-345 11 160 slipknot
Chain Sequence
REHWATRLGLILAMAGNAVGLGNFLRFPVQAAENGGGAFMIPYIIAFLLVGIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVVAIYYVYIESWTLGFAIKFLVGLVPEPP---TDPDSILRPFKEFLYSYIGVPKGDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFTLSLGFGAIITYASYVRKDQDIVLSGLTAATLNEKAEVILGGSISIPAAVAFFGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLTSSIAIMQPMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFWAGTIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRYITPAFLAVLLVVWAREYIPKIMEETHWTVWITRFYIIGLFLFLTFLVFLAERRRN
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.2 12-288 277 1-11 299-502 289-298 11 204 slipknot
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3.2 12-309 298 1-11 318-502 310-317 11 185 slipknot
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3.2 13-332 320 1-12 346-502 333-345 12 157 slipknot
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4.1 12-323 312 1-2, 330-502 3-11, 324-329 2 173 slipknot
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4.1 11-299 289 1-5, 307-502 6-10, 300-306 5 196 slipknot
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3.2 15-314 300 1-8, 319-502 9-14, 315-318 8 184 slipknot
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2.1 41-407 367 408-502 1-16 17-40 16 94 slipknot
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1.1 25-283 259 1-18, 288-502 19-24, 284-287 18 215 slipknot
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2.1 29-356 328 1-18, 383-502 19-28, 357-382 18 120 slipknot
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2.1 43-350 308 1-20, 397-502 21-42, 351-396 20 106 slipknot
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2.1 38-256 219 1-21, 270-502 22-37, 257-269 21 233 slipknot
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1.1 40-245 206 1-25, 254-502 26-39, 246-253 25 249 slipknot
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2.1 42-273 232 1-25, 285-502 26-41, 274-284 25 218 slipknot
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2.1 42-284 243 1-25, 292-502 26-41, 285-291 25 211 slipknot
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1.1 41-257 217 1-37, 263-502 38-40, 258-262 37 240 slipknot
missing residues 128-130
publication title Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
pubmed doi rcsb
structure length 502
molecule tags Transport protein
source organism Aquifex aeolicus
sequence length 505
total genus Genus: 209
molecule keywords Transporter
ec nomenclature
pdb deposition date 2011-11-23
KnotProt deposition date 2014-08-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00209 SNF Sodium:neurotransmitter symporter family
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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