3USJA

Crystal structure of leut bound to l-leucine in space group p21 from lipid bicelles
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
  • Chain breaks within knot 41 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Genus: 210
Slipknot S +31 41 +31

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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 37-261 225 262-505 1-20 21-36 20 243 slipknot
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41 12-293 282 1-11 345-505 294-344 11 161 slipknot
Chain Sequence
REHWATRLGLILAMAGNAVGLGNFLRFPVQAAENGGGAFMIPYIIAFLLVGIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVVAIYYVYIESWTLGFAIKFLVGLVPEPP---TDPDSILRPFKEFLYSYIGVPKGDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFTLSLGFGAIITYASYVRKDQDIVLSGLTAATLNEKAEVILGGSISIPAAVAFFGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLTSSIAIMQPMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFWAGTIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRYITPAFLAVLLVVWAREYIPKIMEETHWTVWITRFYIIGLFLFLTFLVFLAERRRN
Whole chain analysis

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Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.2 11-286 276 1-10 300-502 287-299 10 203 slipknot
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4.1 7-299 293 1-6 307-502 300-306 6 196 slipknot
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4.1 8-310 303 1-7 317-502 311-316 7 186 slipknot
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3.2 13-332 320 1-12 345-502 333-344 12 158 slipknot
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4.1 9-299 291 1-6, 305-502 7-8, 300-304 6 198 slipknot
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2.1 29-487 459 1-16, 502-502 17-28, 488-501 16 1 slipknot
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1.1 24-272 249 1-17, 284-502 18-23, 273-283 17 219 slipknot
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2.1 42-353 312 1-17, 398-502 18-41, 354-397 17 105 slipknot
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2.1 43-405 363 406-502 1-17 18-42 17 96 slipknot
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1.1 36-242 207 1-21, 252-502 22-35, 243-251 21 251 slipknot
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1.1 39-275 237 1-25, 293-502 26-38, 276-292 25 210 slipknot
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1.1 42-275 234 1-38, 293-502 39-41, 276-292 38 210 slipknot
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2.1 42-259 218 1-34, 275-502 35-41, 260-274 34 228 slipknot
sequence length 505
structure length 502
publication title Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
pubmed doi rcsb
molecule tags Transport protein
molecule keywords Transporter
source organism Aquifex aeolicus
missing residues 128-130
total genus Genus: 210
ec nomenclature
pdb deposition date 2011-11-23
KnotProt deposition date 2014-08-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00209 SNF Sodium:neurotransmitter symporter family
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
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How to cite
KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling