3USKA

Crystal structure of leut bound to l-leucine in space group p21 from lipid bicelles
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
  • Chain breaks within knot 41 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Slipknot S +31 41 +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 39-264 226 265-505 1-23 24-38 23 240 slipknot
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41 13-296 284 1-12 349-505 297-348 12 157 slipknot
Chain Sequence
REHWATRLGLILAMAGNAVGLGNFLRFPVQAAENGGGAFMIPYIIAFLLVGIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVVAIYYVYIESWTLGFAIKFLVGLVPEPP---TDPDSILRPFKEFLYSYIGVPKGDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFTLSLGFGAIITYASYVRKDQDIVLSGLTAATLNEKAEVILGGSISIPAAVAFFGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLTSSIAIMQPMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFWAGTIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRYITPAFLAVLLVVWAREYIPKIMEETHWTVWITRFYIIGLFLFLTFLVFLAERRRN
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.2 13-286 274 1-12 298-502 287-297 12 205 slipknot
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4.1 9-298 290 1-8 308-502 299-307 8 195 slipknot
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4.1 9-307 299 1-8 315-502 308-314 8 188 slipknot
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4.1 12-334 323 1-11 348-502 335-347 11 155 slipknot
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2.1 27-270 244 1-18, 279-502 19-26, 271-278 18 224 slipknot
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1.1 24-278 255 1-18, 288-502 19-23, 279-287 18 215 slipknot
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2.1 40-353 314 1-18, 401-502 19-39, 354-400 18 102 slipknot
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2.1 32-412 381 1-18, 438-502 19-31, 413-437 18 65 slipknot
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2.1 35-442 408 1-18, 476-502 19-34, 443-475 18 27 slipknot
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2.1 41-401 361 402-502 1-19 20-40 19 100 slipknot
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2.1 26-278 253 1-23, 288-502 24-25, 279-287 23 215 slipknot
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1.1 35-243 209 1-23, 257-502 24-34, 244-256 23 246 slipknot
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1.1 41-274 234 1-29, 291-502 30-40, 275-290 29 212 slipknot
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2.1 40-290 251 1-29, 292-502 30-39, 291-291 29 211 slipknot
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1.1 40-272 233 1-33, 275-502 34-39, 273-274 33 228 slipknot
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1.1 40-253 214 1-34, 260-502 35-39, 254-259 34 243 slipknot
missing residues 128-130
publication title Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
pubmed doi rcsb
structure length 502
molecule tags Transport protein
source organism Aquifex aeolicus
sequence length 505
total genus Genus: 210
molecule keywords Transporter
ec nomenclature
pdb deposition date 2011-11-23
KnotProt deposition date 2014-08-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00209 SNF Sodium:neurotransmitter symporter family
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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