3USMA

Crystal structure of leut bound to l-selenomethionine in space group c2 from lipid bicelles (collected at 1.2 a)
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
  • Chain breaks within knot 41 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Genus: 211
Slipknot S +31 41 +31

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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 37-263 227 264-505 1-24 25-36 24 241 slipknot
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41 13-293 281 1-12 349-505 294-348 12 157 slipknot
Chain Sequence
REHWATRLGLILAMAGNAVGLGNFLRFPVQAAENGGGAFMIPYIIAFLLVGIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVVAIYYVYIESWTLGFAIKFLVGLVPEPP---TDPDSILRPFKEFLYSYIGVPKGDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFTLSLGFGAIITYASYVRKDQDIVLSGLTAATLNEKAEVILGGSISIPAAVAFFGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLTSSIAIMQPMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFWAGTIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRYITPAFLAVLLVVWAREYIPKIMEETHWTVWITRFYIIGLFLFLTFLVFLAERRRNM
Whole chain analysis

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Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.2 11-287 277 1-10 300-502 288-299 10 203 slipknot
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4.1 10-299 290 1-9 306-502 300-305 9 197 slipknot
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4.1 9-326 318 1-8 332-502 327-331 8 171 slipknot
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3.2 18-331 314 1-17 347-502 332-346 17 156 slipknot
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4.1 10-307 298 1-2, 314-502 3-9, 308-313 2 189 slipknot
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1.1 22-274 253 1-16, 286-502 17-21, 275-285 16 217 slipknot
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2.1 30-416 387 1-17, 430-502 18-29, 417-429 17 73 slipknot
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2.1 41-402 362 403-502 1-18 19-40 18 99 slipknot
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2.1 31-253 223 1-19, 265-502 20-30, 254-264 19 238 slipknot
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1.1 25-271 247 1-19, 283-502 20-24, 272-282 19 220 slipknot
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2.1 26-271 246 1-24, 283-502 25-25, 272-282 24 220 slipknot
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2.1 29-264 236 1-21, 272-502 22-28, 265-271 21 231 slipknot
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1.1 31-242 212 1-23, 253-502 24-30, 243-252 23 250 slipknot
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1.1 41-274 234 1-27, 291-502 28-40, 275-290 27 212 slipknot
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2.1 40-243 204 1-31, 254-502 32-39, 244-253 31 249 slipknot
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2.1 41-260 220 1-34, 275-502 35-40, 261-274 34 228 slipknot
sequence length 505
structure length 502
publication title Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
pubmed doi rcsb
molecule tags Transport protein
molecule keywords Transporter
source organism Aquifex aeolicus
missing residues 128-130
total genus Genus: 211
ec nomenclature
pdb deposition date 2011-11-23
KnotProt deposition date 2014-08-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00209 SNF Sodium:neurotransmitter symporter family
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
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How to cite
KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling